HSPA9 and DNAJC19

Number of citations of the paper that reports this interaction (PMID 20053669)
12

Data Source:
BioGRID (enzymatic study, enzymatic study)

		HSPA9	DNAJC19
Gene Name		heat shock 70kDa protein 9 (mortalin)	DnaJ (Hsp40) homolog, subfamily C, member 19
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm Mitochondrion Focal Adhesion Mitochondrial Nucleoid Extracellular Vesicular Exosome	Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane Protein Complex
	Molecular Function	Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Poly(A) RNA Binding Unfolded Protein Binding	Protein Binding
	Biological Process	Protein Folding Protein Export From Nucleus Protein Targeting To Mitochondrion Negative Regulation Of Apoptotic Process Cellular Protein Metabolic Process	Protein Folding Protein Targeting To Mitochondrion Visual Perception Cellular Protein Metabolic Process Genitalia Development
Pathways		Mitochondrial protein import	Mitochondrial protein import
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: APP DNAJA3 DNAJC19 DNLZ FGF1 HSP90B1 HSPBP1 LSM8 MVD NELFB SUMO4 TP53 XPO1 YKT6 YWHAG	3 interactors: APP HSPA9 PAM16
Entrez ID		3313	131118
HPRD ID		02770	12349
Ensembl ID		ENSG00000113013	ENSG00000205981
Uniprot IDs		P38646	Q96DA6
PDB IDs		3N8E
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Metabolic Process Regulation Of Protein Phosphorylation Protein Folding Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Protein Localization Regulation Of Protein Kinase Activity Regulation Of Cellular Protein Metabolic Process Mitochondrial DNA Metabolic Process Regulation Of Phosphorylation Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Protein Transport Establishment Of Protein Localization Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Intracellular Transport Mitochondrial Genome Maintenance Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Catalytic Activity Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cellular Localization Response To Abiotic Stimulus Positive Regulation Of Cellular Metabolic Process Neuromuscular Junction Development Neuron Apoptotic Process Positive Regulation Of Mitochondrion Organization Cytoplasmic Transport Establishment Of Localization In Cell Immune Response Branch Elongation Involved In Ureteric Bud Branching Positive Regulation Of Proteolysis Neuron Death T Cell Differentiation In Thymus Negative Regulation Of Cellular Metabolic Process Cellular Protein Localization Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cell Aging Innate Immune Response Membrane Organization Negative Regulation Of Macromitophagy Synaptic Growth At Neuromuscular Junction Actin Rod Assembly Oligodendrocyte Apoptotic Process Regulation Of Mitochondrion Organization Mitochondrion Organization Negative Regulation Of Hydrolase Activity Intracellular Protein Transport	Protein Targeting To Mitochondrion Protein Localization To Mitochondrion Mitochondrial Transport Synaptic Growth At Neuromuscular Junction Intracellular Transport Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Establishment Of Localization In Cell Establishment Of Protein Localization To Organelle Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Mitochondrion Organization Negative Regulation Of Hydrolase Activity Protein Import Into Mitochondrial Matrix Protein Targeting Negative Regulation Of ATPase Activity Cellular Localization Neuron Remodeling Protein Localization To Organelle Cellular Copper Ion Homeostasis Cytoplasmic Transport Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Catalytic Activity Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Intracellular Protein Transport Endoplasmic Reticulum Calcium Ion Homeostasis Protein Export From Nucleus Neuron Recognition RNA Polyadenylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of ATPase Activity Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Intracellular Protein Transmembrane Transport Cellular Protein Metabolic Process Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Protein Transmembrane Transport Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity
Tagcloud ?		5q 5q31 cfu collectively colony comprehensively defect del deleted haploinsufficiency haploinsufficient hematopoiesis heterozygous homozygous implicate intrinsic knockdown knockout lethal lymphopoiesis malignancies observe preb progenitors rnai stat5 supporting viable zebrafish	abomasum actb b2m blat butterfat calculating cops7a coro1b cows eif3k emd gapdh genorm golga5 goodness gpr175 icg linoleic lipogenic marveld1 mine mrpl39 mtg1 normalization qpcr supplements unsupplemented uxt verification
Tagcloud (Difference) ?		5q 5q31 cfu collectively colony comprehensively defect del deleted haploinsufficiency haploinsufficient hematopoiesis heterozygous homozygous implicate intrinsic knockdown knockout lethal lymphopoiesis malignancies observe preb progenitors rnai stat5 supporting viable zebrafish	abomasum actb b2m blat butterfat calculating cops7a coro1b cows eif3k emd gapdh genorm golga5 goodness gpr175 icg linoleic lipogenic marveld1 mine mrpl39 mtg1 normalization qpcr supplements unsupplemented uxt verification
Tagcloud (Intersection) ?