HNRNPH1 and DDX5

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		HNRNPH1	DDX5
Gene Name		heterogeneous nuclear ribonucleoprotein H1 (H)	DEAD (Asp-Glu-Ala-Asp) box helicase 5
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Membrane Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Nucleolus Membrane Ribonucleoprotein Complex Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Poly(U) RNA Binding Poly(A) RNA Binding	Transcription Coactivator Activity RNA Helicase Activity ATP-dependent RNA Helicase Activity Protein Binding Calmodulin Binding ATP Binding Enzyme Binding Estrogen Receptor Binding Pre-mRNA Binding Poly(A) RNA Binding Calcium-dependent Protein Binding Androgen Receptor Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing Gene Expression Regulation Of RNA Splicing	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome In Utero Embryonic Development Transcription, DNA-templated Circadian Rhythm Cell Growth Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Viral Genome Replication Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Androgen Receptor Signaling Pathway Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Skeletal Muscle Cell Differentiation
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: APBB1 CRMP1 DDX5 ERG HIPK3 HNRNPF HNRNPH3 KHSRP NCBP1 NCBP2 NDRG1 PIN1 RALY SF1 SF3B4 SREK1 SUMO4 TCERG1 TOM1L1 YWHAG YWHAQ	34 interactors: AKAP8 CALM1 CREBBP DDX17 DHX9 EP300 ESR1 ESR2 FBL HNRNPA0 HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK IL7R KHDRBS1 MAPKAPK2 NCOA1 NCOA2 NCOA3 NDRG1 PIAS1 PIK3CA PIN1 PRKCA PSMA3 RBFOX2 RBM10 RBM4 SMAD3 SP1 TNNT1 TP53 WBP11
Entrez ID		3187	1655
HPRD ID		03021	01615
Ensembl ID		ENSG00000169045	ENSG00000108654
Uniprot IDs		E9PCY7 G8JLB6 P31943	J3KTA4 P17844
PDB IDs		2LXU	3FE2 4A4D
Enriched GO Terms of Interacting Partners?		RNA Splicing RNA Splicing, Via Transesterification Reactions MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Processing RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process MRNA Cis Splicing, Via Spliceosome Cellular Metabolic Process Regulation Of MRNA Processing Transcription, DNA-templated Regulation Of RNA Metabolic Process RNA Biosynthetic Process Regulation Of RNA Splicing MRNA Transport Histone MRNA Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Gene Expression RNA Transport Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway RNA Localization Regulation Of Viral Process MRNA Catabolic Process 7-methylguanosine MRNA Capping Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Ribonucleoprotein Complex Assembly 7-methylguanosine RNA Capping RNA Catabolic Process Termination Of RNA Polymerase II Transcription Intrinsic Apoptotic Signaling Pathway Spliceosomal SnRNP Assembly Positive Regulation Of Viral Transcription Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Thymidylate Synthase Biosynthetic Process Negative Regulation Of Potassium Ion Export Peptidyl-amino Acid Modification Positive Regulation Of Intracellular Transport Positive Regulation Of Mitochondrion Organization Apoptotic Process Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process	Gene Expression RNA Metabolic Process RNA Processing Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Processing Rhythmic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Splicing MRNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Cellular Response To Organic Substance Positive Regulation Of Cellular Biosynthetic Process Signal Transduction Positive Regulation Of Metabolic Process Cellular Metabolic Process Positive Regulation Of Gene Expression Signaling Response To Organic Substance Regulation Of Metabolic Process Intracellular Receptor Signaling Pathway Cell Communication Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Stimulus Regulation Of Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Immune System Process Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Signaling Negative Regulation Of Cellular Metabolic Process Chromatin Organization Histone Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Metabolic Process Response To Stimulus Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Vagina Development Histone Modification Transcription, DNA-templated
Tagcloud ?		cct5 cd68 ddx5 enterovirus ft1dm fulminant helicase hspa1l infiltrated inflamed insulitis iqgap1 lamin lcp1 lmnb1 microdissection moesin msn pdg phosphogluconate phosphorylase plastin protein1 psme1 samhd1 serpin serpinb6 tymp wars	cct5 cd68 enterovirus ft1dm fulminant helicase hnrnph1 hspa1l infiltrated inflamed insulitis iqgap1 lamin lcp1 lmnb1 microdissection moesin msn pdg phosphogluconate phosphorylase plastin protein1 psme1 samhd1 serpin serpinb6 tymp wars
Tagcloud (Difference) ?
Tagcloud (Intersection) ?		cct5 cd68 ddx5 enterovirus ft1dm fulminant helicase hnrnph1 hspa1l infiltrated inflamed insulitis iqgap1 lamin lcp1 lmnb1 microdissection moesin msn pdg phosphogluconate phosphorylase plastin protein1 psme1 samhd1 serpin serpinb6 tymp wars