CNOT7 and CNOT6

Number of citations of the paper that reports this interaction (PMID 10637334)
50

Data Source:
HPRD (two hybrid)

		CNOT7	CNOT6
Gene Name		CCR4-NOT transcription complex, subunit 7	CCR4-NOT transcription complex, subunit 6
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic MRNA Processing Body Nucleus Cytosol Membrane CCR4-NOT Complex	Nucleus Cytosol Membrane CCR4-NOT Complex
	Molecular Function	3'-5'-exoribonuclease Activity Sequence-specific DNA Binding Transcription Factor Activity RNA Binding Exoribonuclease Activity Poly(A)-specific Ribonuclease Activity Signal Transducer Activity Protein Binding Metal Ion Binding	RNA Binding Exoribonuclease Activity Poly(A)-specific Ribonuclease Activity Protein Binding Metal Ion Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Poly(A) Tail Shortening Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Carbohydrate Metabolic Process Transcription, DNA-templated Regulation Of Translation Signal Transduction Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Gene Expression Negative Regulation Of Gene Expression Gene Silencing By RNA Cytoplasmic MRNA Processing Body Assembly Gene Silencing By MiRNA Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Positive Regulation Of MRNA Catabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Poly(A) Tail Shortening Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Translation Positive Regulation Of Cell Proliferation Gene Expression Positive Regulation Of Cytoplasmic MRNA Processing Body Assembly Gene Silencing By MiRNA Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, No-go Decay RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Positive Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
Pathways		Deadenylation of mRNA Deadenylation-dependent mRNA decay	Deadenylation of mRNA Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: APP BTG1 BTG2 BTG3 CDK1 CDK2 CDK4 CDK6 CNOT6 FOXC2 HOXD4 IKBKG PABPC1 TNRC6A TOB1 TOB2	3 interactors: CNOT7 CNOT8 PABPC1
Entrez ID		29883	57472
HPRD ID		05370	12341
Ensembl ID		ENSG00000198791	ENSG00000113300
Uniprot IDs		Q9UIV1	Q9ULM6
PDB IDs		2D5R 4GMJ
Enriched GO Terms of Interacting Partners?		Regulation Of Translation Regulation Of Gene Expression Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of MRNA 3'-end Processing Regulation Of MRNA 3'-end Processing Regulation Of Protein Metabolic Process Positive Regulation Of MRNA Catabolic Process Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Notch Signaling Pathway Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cell Proliferation G1/S Transition Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Gene Silencing By RNA Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Cellular Process Regulation Of Cell Cycle MRNA 3'-end Processing Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Negative Regulation Of Translation Regulation Of MRNA Processing Positive Regulation Of Cell Cycle Regulation Of Cell Differentiation Gene Silencing Regulation Of Nitrogen Compound Metabolic Process RNA 3'-end Processing Positive Regulation Of Mitotic Cell Cycle Dentate Gyrus Development Negative Regulation Of Cell Differentiation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Gene Expression Positive Regulation Of Cell Proliferation Cell Division MRNA Polyadenylation Regulation Of Apoptotic Process Gene Silencing By MiRNA RNA Polyadenylation	Positive Regulation Of MRNA Catabolic Process Nuclear-transcribed MRNA Poly(A) Tail Shortening Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Gene Silencing By RNA MRNA 3'-end Processing Gene Silencing RNA 3'-end Processing Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Positive Regulation Of MRNA 3'-end Processing Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulation Of MRNA 3'-end Processing Regulation Of Translation Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic RNA Phosphodiester Bond Hydrolysis, Exonucleolytic MRNA Processing Gene Silencing By MiRNA Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression Posttranscriptional Gene Silencing MRNA Metabolic Process RNA Processing Regulation Of MRNA Processing Cellular Macromolecule Catabolic Process RNA Phosphodiester Bond Hydrolysis Negative Regulation Of Gene Expression Regulation Of Gene Expression, Epigenetic Catabolic Process Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nucleic Acid Phosphodiester Bond Hydrolysis Regulation Of Cellular Protein Metabolic Process Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Regulation Of Protein Metabolic Process Cytoplasmic MRNA Processing Body Assembly Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cell Proliferation RNA Metabolic Process Positive Regulation Of Metabolic Process Gene Expression MRNA Stabilization Positive Regulation Of Cell Proliferation Cellular Macromolecule Biosynthetic Process MRNA Polyadenylation Macromolecule Biosynthetic Process RNA Polyadenylation Regulation Of MRNA Stability Regulation Of RNA Metabolic Process
Tagcloud ?		actr1a backgrounds bbs2 bovines c2orf29 cq cycling dnajc17 endometrium establishes friesian gapdh genorm holstein normalise normalised normfinder oestrus oxtr oxytocin ppia ranbp10 rps15a rps9 slc30a6 suitability suz12 uxt znf131	adam33 allergen allergens allergic black boston cockroach dataset dust fcer1a genotypic haplotype haplotypes house il5ra jak3 maml1 marginally mite nod1 rs11739089 rs12136904t rs6665683 rs6665683t rs7851969 sensitization sensitizations snps strongest
Tagcloud (Difference) ?		actr1a backgrounds bbs2 bovines c2orf29 cq cycling dnajc17 endometrium establishes friesian gapdh genorm holstein normalise normalised normfinder oestrus oxtr oxytocin ppia ranbp10 rps15a rps9 slc30a6 suitability suz12 uxt znf131	adam33 allergen allergens allergic black boston cockroach dataset dust fcer1a genotypic haplotype haplotypes house il5ra jak3 maml1 marginally mite nod1 rs11739089 rs12136904t rs6665683 rs6665683t rs7851969 sensitization sensitizations snps strongest
Tagcloud (Intersection) ?