LGALS13 and ANXA2

Number of citations of the paper that reports this interaction (PMID 15009185)
18

Data Source:
HPRD (in vitro)

		LGALS13	ANXA2
Gene Name		lectin, galactoside-binding, soluble, 13	annexin A2
Image
Gene Ontology Annotations	Cellular Component		Ruffle Basement Membrane Extracellular Space Nucleus Lysosomal Membrane Endosome Early Endosome Lipid Particle Plasma Membrane Cell Cortex Cell Surface Membrane Extrinsic Component Of Plasma Membrane Midbody Extracellular Matrix Late Endosome Membrane Vesicle Myelin Sheath Adaxonal Region Sarcolemma Melanosome Schmidt-Lanterman Incisure Protein Complex Macropinosome Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Lysophospholipase Activity Protein Binding Carbohydrate Binding	Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Cytoskeletal Protein Binding Rab GTPase Binding Phospholipase A2 Inhibitor Activity S100 Protein Binding Poly(A) RNA Binding Calcium-dependent Protein Binding
	Biological Process	Phospholipid Metabolic Process Apoptotic Process	Angiogenesis Membrane Raft Assembly Positive Regulation Of Protein Phosphorylation Membrane Budding Body Fluid Secretion Collagen Fibril Organization Positive Regulation Of Vesicle Fusion Osteoclast Development Fibrinolysis Negative Regulation Of Catalytic Activity Positive Regulation Of Fibroblast Proliferation Positive Regulation Of Binding Protein Heterotetramerization Protein Targeting To Plasma Membrane
Pathways			Dissolution of Fibrin Clot Orphan transporters
Drugs			Tenecteplase
Diseases
GWAS
Protein-Protein Interactions		6 interactors: ACTB ACTG1 ANXA2 HOXA1 NUFIP2 PACSIN3	31 interactors: APOH APP CD99 CDC42 CEACAM1 CTSB DYSF GRB2 HMGA1 LGALS13 LYPLA1 MAP3K4 MYOC PHB PLA1A PLAT PLG POT1 PRKCA PRKCB S100A10 S100A4 S100A6 SOS1 SRC STAT6 TERF1 TERT TP53 TRPV5 YWHAQ
Entrez ID		29124	302
HPRD ID		16375	01061
Ensembl ID		ENSG00000105198	ENSG00000182718
Uniprot IDs		Q9UHV8	P07355
PDB IDs		1F87	1W7B 1XJL 2HYU 2HYV 2HYW 4DRW 4HRH
Enriched GO Terms of Interacting Partners?		Membrane Organization Platelet Aggregation Axon Guidance Neural Nucleus Development Retina Homeostasis Vesicle-mediated Transport Axonogenesis Regulation Of Body Fluid Levels Axon Development Adherens Junction Organization Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Cell Development Ephrin Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Neuron Projection Morphogenesis Endocytosis Optokinetic Behavior Abducens Nerve Formation Cell Morphogenesis Involved In Differentiation Neuron Projection Development Facial Nucleus Development Cell Projection Morphogenesis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Cell Part Morphogenesis Anatomical Structure Morphogenesis Tissue Homeostasis Rhombomere 4 Development Semicircular Canal Formation Neuron Development Platelet Activation Cell Junction Assembly Plasma Membrane Organization Cell-cell Junction Organization Anatomical Structure Formation Involved In Morphogenesis Rhombomere 3 Development Rhombomere 5 Development Cell Morphogenesis Multicellular Organismal Homeostasis Neuron Differentiation Cell Projection Organization Phagocytosis Fc Receptor Signaling Pathway Locomotion Immune Response-activating Cell Surface Receptor Signaling Pathway Organelle Organization Embryonic Neurocranium Morphogenesis Homotypic Cell-cell Adhesion	Blood Coagulation Hemostasis Wound Healing Response To Wounding Regulation Of Body Fluid Levels Platelet Activation Positive Regulation Of Cellular Component Biogenesis Leukocyte Migration Positive Regulation Of Signal Transduction Positive Regulation Of Organelle Organization ERBB Signaling Pathway Cell Activation Regulation Of Signaling Telomere Maintenance Via Telomerase Regulation Of Signal Transduction Positive Regulation Of Intracellular Signal Transduction Developmental Process Regulation Of Apoptotic Process Response To Stress Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Cell Cycle Regulation Of Organelle Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Histone H3-T6 Phosphorylation Cellular Component Assembly Regulation Of Cell Death Epidermal Growth Factor Receptor Signaling Pathway Cell Aging Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Catalytic Activity RNA-dependent DNA Replication Regulation Of ERBB Signaling Pathway Age-dependent Telomere Shortening Telomere Formation Via Telomerase Regulation Of Cell-substrate Adhesion Negative Regulation Of Cellular Metabolic Process Cell Differentiation Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Signal Transduction Innate Immune Response Response To Stimulus Regulation Of Intracellular Signal Transduction Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Cell Adhesion Immune System Process Cell Migration Regulation Of Blood Coagulation Vascular Endothelial Growth Factor Receptor Signaling Pathway Membrane Organization
Tagcloud ?			annexin apoptotic biological biomarker candidate collectively contributes encoding fully gemcitabine herein intracellular kappab localization mediates mia nf nucleus p50 paca2 pancreatic resting suppresses translocated understood upregulated upregulation y23a
Tagcloud (Difference) ?			annexin apoptotic biological biomarker candidate collectively contributes encoding fully gemcitabine herein intracellular kappab localization mediates mia nf nucleus p50 paca2 pancreatic resting suppresses translocated understood upregulated upregulation y23a
Tagcloud (Intersection) ?