LAMTOR2 and LAMTOR3

Number of citations of the paper that reports this interaction (PMID 11266467)
54

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		LAMTOR2	LAMTOR3
Gene Name		late endosomal/lysosomal adaptor, MAPK and MTOR activator 2	late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosomal Membrane Late Endosome Extracellular Vesicular Exosome Ragulator Complex	Focal Adhesion Extracellular Vesicular Exosome Ragulator Complex
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Protein Complex Scaffold	Guanyl-nucleotide Exchange Factor Activity Protein Binding Protein Complex Scaffold
	Biological Process	Activation Of MAPKK Activity Cell Growth Positive Regulation Of TOR Signaling Cellular Protein Localization Positive Regulation Of GTPase Activity Cellular Response To Amino Acid Stimulus	Positive Regulation Of TOR Signaling Cellular Protein Localization Positive Regulation Of GTPase Activity Cellular Response To Amino Acid Stimulus
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: LAMTOR3	16 interactors: ADAMTS10 BHMT CEBPZ CPNE6 IBTK LAMTOR2 MAP2K1 MAP2K2 MAPK1 MAPK3 MBD2 NIF3L1 PDE4DIP QARS SUFU UBR1
Entrez ID		28956	8649
HPRD ID		17463	04485
Ensembl ID		ENSG00000116586	ENSG00000109270
Uniprot IDs		Q9Y2Q5	Q9UHA4
PDB IDs			1SKO 2ZL1 3CPT
Enriched GO Terms of Interacting Partners?		Positive Regulation Of TOR Signaling Regulation Of TOR Signaling Cellular Response To Amino Acid Stimulus	Regulation Of Golgi Inheritance Regulation Of Golgi Organization Regulation Of Early Endosome To Late Endosome Transport Activation Of MAPKK Activity Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Cellular Response To Organonitrogen Compound Response To Organonitrogen Compound Vascular Endothelial Growth Factor Receptor Signaling Pathway Activation Of Protein Kinase Activity Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of MAPK Activity Activation Of Innate Immune Response Insulin Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Caveolin-mediated Endocytosis Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Protein Kinase Activity Positive Regulation Of Innate Immune Response Regulation Of Stress-activated MAPK Cascade Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Intracellular Transport Regulation Of Kinase Activity Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Kinase Activity Positive Regulation Of MAP Kinase Activity Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Ras Protein Signal Transduction MAPK Cascade Neurotrophin Signaling Pathway Positive Regulation Of Kinase Activity Fc-epsilon Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process Regulation Of Innate Immune Response
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