GRIA3 and PPM1G

Number of citations of the paper that reports this interaction (PMID 14663150)
12

Data Source:
HPRD (in vitro, in vivo)

		GRIA3	PPM1G
Gene Name		glutamate receptor, ionotropic, AMPA 3	protein phosphatase, Mg2+/Mn2+ dependent, 1G
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Cell Junction Dendrite Endocytic Vesicle Membrane Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Selective Glutamate Receptor Complex Postsynaptic Membrane	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Extracellular-glutamate-gated Ion Channel Activity	Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding
	Biological Process	Transport Glutamate Receptor Signaling Pathway Synaptic Transmission Ion Transmembrane Transport Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic	Protein Dephosphorylation Cell Cycle Arrest Peptidyl-threonine Dephosphorylation
Pathways		Trafficking of GluR2-containing AMPA receptors Activation of NMDA receptor upon glutamate binding and postsynaptic events Activation of AMPA receptors Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity Trafficking of AMPA receptors Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Unblocking of NMDA receptor, glutamate binding and activation Transmission across Chemical Synapses
Drugs		L-Glutamic Acid Lithium Aniracetam
Diseases
GWAS			Hypertriglyceridemia ( 23505323)
Protein-Protein Interactions		11 interactors: ADRB2 GRIA2 GRIP1 GRIP2 GZMB LYN NSF PICK1 PPM1G SDCBP SQSTM1	10 interactors: FBXO38 GRIA3 HIST3H3 LRPAP1 MSL1 MTNR1B RPS6KA1 TERF1 TERF2 TERF2IP
Entrez ID		2892	5496
HPRD ID		02378	09237
Ensembl ID		ENSG00000125675	ENSG00000115241
Uniprot IDs		P42263 Q17R51 Q5XKG2	O15355 Q6IAU5
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell-cell Signaling Synaptic Transmission Signaling Cell Communication Regulation Of Vesicle-mediated Transport Intracellular Transport Positive Regulation Of Cellular Metabolic Process Regulation Of Exocytosis Response To Extracellular Stimulus Protein Localization Cellular Response To Extracellular Stimulus Establishment Of Localization In Cell Regulation Of Signaling Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Metabolic Process Cellular Localization Positive Regulation Of Phosphorylation Apoptotic Signaling Pathway Signal Transduction Positive Regulation Of Oligodendrocyte Progenitor Proliferation Negative Regulation Of Mast Cell Proliferation Enzyme Linked Receptor Protein Signaling Pathway Protein Localization To Membrane Neuron Development Response To External Stimulus Response To Nutrient Levels Regulation Of Cellular Localization Intracellular Signal Transduction Ephrin Receptor Signaling Pathway Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Golgi Vesicle Docking Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Glial Cell Development Neuron Differentiation Cell Projection Organization Tolerance Induction To Self Antigen Fc Receptor Mediated Inhibitory Signaling Pathway Positive Regulation Of Dendritic Cell Apoptotic Process Vasodilation By Norepinephrine-epinephrine Involved In Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Extracellular Vesicular Exosome Assembly Cellular Response To Starvation Positive Regulation Of Signal Transduction Cell Differentiation Regulation Of Phosphorylation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Immune Response-inhibiting Cell Surface Receptor Signaling Pathway Granzyme-mediated Apoptotic Signaling Pathway	Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Telomere Maintenance Regulation Of Telomere Maintenance RNA-dependent DNA Replication Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomere Maintenance Via Telomere Lengthening Telomeric Loop Formation Age-dependent Telomere Shortening Telomere Maintenance Via Telomere Shortening Protection From Non-homologous End Joining At Telomere Telomere Capping Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Chromosome Organization Replicative Cell Aging Regulation Of Nuclear Cell Cycle DNA Replication Negative Regulation Of DNA Metabolic Process Chromosome Organization Regulation Of Chromosome Organization Protein Localization To Chromosome Homeostatic Process DNA Replication Negative Regulation Of DNA Replication Cell Aging Negative Regulation Of DNA Recombination At Telomere DNA Metabolic Process Positive Regulation Of Hepatic Stellate Cell Activation Regulation Of DNA Replication Negative Regulation Of Beta-amyloid Clearance Synaptic Transmission Chromatin Modification Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Chromatin Organization Negative Regulation Of Telomere Maintenance Via Telomerase Regulation Of Beta-amyloid Clearance Organelle Organization Negative Regulation Of Telomerase Activity Positive Regulation Of Telomere Maintenance Regulation Of Cellular Component Organization Cell-cell Signaling Regulation Of Organelle Organization Regulation Of Telomere Maintenance Via Telomerase Histone H4-K16 Acetylation Positive Regulation Of Microtubule Polymerization Regulation Of Double-strand Break Repair Via Homologous Recombination Negative Regulation Of Cellular Metabolic Process Regulation Of Telomerase Activity Regulation Of Translation In Response To Stress Aging Extracellular Negative Regulation Of Signal Transduction
Tagcloud ?		agouti camk2g cd47 chances clstn2 consonant enpp1 epha5a gad2 grin2b kif minipumps myo5a negr1 neuroplasticity ntrk2 ntrk3 ppp3r1 prdx1 predecessors serotonine slc2a4 sv2b syn2 synaptogenesis synj2 therapeutical venlafaxine vlx
Tagcloud (Difference) ?		agouti camk2g cd47 chances clstn2 consonant enpp1 epha5a gad2 grin2b kif minipumps myo5a negr1 neuroplasticity ntrk2 ntrk3 ppp3r1 prdx1 predecessors serotonine slc2a4 sv2b syn2 synaptogenesis synj2 therapeutical venlafaxine vlx
Tagcloud (Intersection) ?