RUSC1-AS1 and WDR5

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RUSC1-AS1	WDR5
Gene Name		RUSC1 antisense RNA 1	WD repeat domain 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Histone Acetyltransferase Complex Nucleus Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex Histone Methyltransferase Complex Set1C/COMPASS Complex MLL1 Complex
	Molecular Function		Protein Binding Histone Methyltransferase Activity (H3-K4 Specific) Histone Acetyltransferase Activity (H4-K5 Specific) Histone Acetyltransferase Activity (H4-K8 Specific) Histone Acetyltransferase Activity (H4-K16 Specific)
	Biological Process		Skeletal System Development Chromatin Organization Transcription, DNA-templated Positive Regulation Of Gluconeogenesis By Positive Regulation Of Transcription From RNA Polymerase II Promoter Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Histone H3-K4 Methylation
Pathways			Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines HATs acetylate histones RMTs methylate histone arginines
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: PSMA3 WDR5	23 interactors: APP ATN1 CHD8 HIST1H1C HIST4H4 HSF2 IKBKG KMT2A KMT2B KMT2C MBIP MLLT1 POU5F1 PRMT5 PRNP RUSC1-AS1 SETD1A SETD1B SRPK2 SSX2IP TERF2IP TP53 ZXDC
Entrez ID		284618	11091
HPRD ID		08767	10614
Ensembl ID			ENSG00000196363
Uniprot IDs		Q66K80	P61964
PDB IDs			2CNX 2CO0 2G99 2G9A 2GNQ 2H13 2H14 2H68 2H6K 2H6N 2H6Q 2H9L 2H9M 2H9N 2H9P 2O9K 3EG6 3EMH 3MXX 3N0D 3N0E 3P4F 3PSL 3SMR 3UR4 3UVK 3UVL 3UVM 3UVN 3UVO 4A7J 4ERQ 4ERY 4ERZ 4ES0 4ESG 4EWR 4GM3 4GM8 4IA9
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Gluconeogenesis By Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Ketone Metabolic Process Regulation Of Cellular Ketone Metabolic Process By Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gluconeogenesis By Regulation Of Transcription From RNA Polymerase II Promoter Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Positive Regulation Of Gluconeogenesis Histone H3-K4 Methylation Positive Regulation Of Glucose Metabolic Process Regulation Of Gluconeogenesis Histone H3 Acetylation Histone H4 Acetylation Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Transferase Activity Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Ligase Activity DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Histone Lysine Methylation Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Peptidyl-lysine Methylation Regulation Of Cell Cycle Arrest Mitotic DNA Integrity Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Protein Ubiquitination Regulation Of Glucose Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Histone Acetylation Signal Transduction By P53 Class Mediator Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Positive Regulation Of Canonical Wnt Signaling Pathway Histone Methylation Internal Protein Amino Acid Acetylation	Gene Expression Chromatin Organization Regulation Of RNA Metabolic Process Chromosome Organization RNA Metabolic Process Transcription, DNA-templated Regulation Of Gene Expression Histone H3-K4 Methylation RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Histone Methylation Histone Modification Chromatin Modification Cellular Nitrogen Compound Metabolic Process Protein Methylation Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Histone Lysine Methylation Peptidyl-lysine Methylation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Organelle Organization Methylation Peptidyl-lysine Modification Positive Regulation Of Gene Expression Regulation Of Chromosome Organization Positive Regulation Of Transcription, DNA-templated Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Cellular Process Negative Regulation Of Cellular Metabolic Process Peptidyl-amino Acid Modification Regulation Of Transcription From RNA Polymerase II Promoter Neuron Apoptotic Process Cellular Component Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter Neuron Death Cellular Metabolic Process Histone H3-K4 Trimethylation DNA Conformation Change Regulation Of Organelle Organization Cellular Copper Ion Homeostasis Regulation Of Fibroblast Apoptotic Process
Tagcloud ?			acidic allosterically ash2l box compass composed concave dpy30 erythroid forming heterodimer interface kmt2 lysine methyltransferase methyltransferases mll1 mutational rbbp5 referred ryanodine set1 spia spry stimulates switch trithorax trxg wrad
Tagcloud (Difference) ?			acidic allosterically ash2l box compass composed concave dpy30 erythroid forming heterodimer interface kmt2 lysine methyltransferase methyltransferases mll1 mutational rbbp5 referred ryanodine set1 spia spry stimulates switch trithorax trxg wrad
Tagcloud (Intersection) ?