GOT2 and ZDHHC6

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		GOT2	ZDHHC6
Gene Name		glutamic-oxaloacetic transaminase 2, mitochondrial	zinc finger, DHHC-type containing 6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Plasma Membrane Extracellular Vesicular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	L-aspartate:2-oxoglutarate Aminotransferase Activity Kynurenine-oxoglutarate Transaminase Activity Pyridoxal Phosphate Binding Poly(A) RNA Binding L-phenylalanine:2-oxoglutarate Aminotransferase Activity	Zinc Ion Binding Palmitoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity
	Biological Process	Carbohydrate Metabolic Process Glucose Metabolic Process Gluconeogenesis 2-oxoglutarate Metabolic Process Oxaloacetate Metabolic Process Aspartate Metabolic Process Aspartate Biosynthetic Process Aspartate Catabolic Process Glutamate Metabolic Process Cellular Amino Acid Biosynthetic Process Pathogenesis Fatty Acid Transport 4-hydroxyproline Catabolic Process Glutamate Catabolic Process To Aspartate Glutamate Catabolic Process To 2-oxoglutarate Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process Response To Ethanol L-kynurenine Metabolic Process	Protein Palmitoylation
Pathways		Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Amino acid synthesis and interconversion (transamination) Metabolism of carbohydrates Metabolism of amino acids and derivatives
Drugs		Pyridoxal Phosphate L-Aspartic Acid L-Glutamic Acid 4\'-Deoxy-4\'-Acetylyamino-Pyridoxal-5\'-Phosphate
Diseases
GWAS		Aortic root size ( 21223598) QT interval ( 19305408)
Protein-Protein Interactions		10 interactors: APCS CCL21 GAPDH GLRX GLUD1 HSPA8 MDH2 PC THOC7 ZDHHC6	2 interactors: GOT2 KHDRBS1
Entrez ID		2806	64429
HPRD ID		00684	15721
Ensembl ID		ENSG00000125166	ENSG00000023041
Uniprot IDs		E7ERW2 P00505	Q9H6R6
PDB IDs
Enriched GO Terms of Interacting Partners?		Gluconeogenesis Hexose Biosynthetic Process Dicarboxylic Acid Metabolic Process Oxaloacetate Metabolic Process Glucose Metabolic Process Carbohydrate Biosynthetic Process Pathogenesis Hexose Metabolic Process Monosaccharide Metabolic Process Tricarboxylic Acid Metabolic Process Protein Deglutathionylation Positive Regulation Of Myeloid Dendritic Cell Chemotaxis Negative Regulation Of Dendritic Cell Dendrite Assembly Dendritic Cell Dendrite Assembly Negative Regulation Of Fibril Organization Peptidyl-cysteine S-trans-nitrosylation Carboxylic Acid Metabolic Process Negative Regulation By Host Of Viral Exo-alpha-sialidase Activity Negative Regulation By Host Of Viral Glycoprotein Metabolic Process Mesangial Cell-matrix Adhesion Negative Regulation Of Exo-alpha-sialidase Activity Organic Acid Metabolic Process Pyruvate Metabolic Process Regulation Of Dendritic Cell Dendrite Assembly Regulation Of Fibril Organization Small Molecule Metabolic Process Negative Regulation Of Leukocyte Tethering Or Rolling Clathrin Coat Disassembly Peptidyl-cysteine S-nitrosylation Establishment Of T Cell Polarity Oxidation-reduction Process Negative Regulation Of Monocyte Differentiation Glutamate Catabolic Process Positive Regulation Of Dendritic Cell Chemotaxis Cellular Metabolic Process Positive Regulation Of Transport Viral MRNA Export From Host Cell Nucleus Glutamate Biosynthetic Process Cellular Protein Metabolic Process Positive Regulation Of Dendritic Cell Antigen Processing And Presentation Negative Regulation Of Locomotion Biotin Metabolic Process Positive Regulation Of Pseudopodium Assembly Negative Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Dicarboxylic Acid Catabolic Process Chaperone-mediated Protein Complex Assembly Protein Folding Regulation Of Monocyte Differentiation Dendritic Cell Chemotaxis	Glutamate Catabolic Process To 2-oxoglutarate Glutamate Catabolic Process To Aspartate Aspartate Biosynthetic Process Positive Regulation Of RNA Export From Nucleus Fumarate Metabolic Process Aspartate Catabolic Process 4-hydroxyproline Catabolic Process L-kynurenine Metabolic Process Glutamate Catabolic Process Aspartate Metabolic Process Regulation Of RNA Export From Nucleus Kynurenine Metabolic Process Dicarboxylic Acid Catabolic Process Positive Regulation Of Translational Initiation 2-oxoglutarate Metabolic Process Oxaloacetate Metabolic Process 4-hydroxyproline Metabolic Process Cellular Modified Amino Acid Catabolic Process Glutamate Metabolic Process Gluconeogenesis Fatty Acid Transport Hexose Biosynthetic Process Regulation Of Translational Initiation Positive Regulation Of Translation Cellular Ketone Metabolic Process Dicarboxylic Acid Metabolic Process Positive Regulation Of Nucleocytoplasmic Transport G2/M Transition Of Mitotic Cell Cycle Cellular Amino Acid Catabolic Process Monocarboxylic Acid Transport Cellular Amino Acid Biosynthetic Process Response To Ethanol Glucose Metabolic Process Cell Cycle Arrest Carbohydrate Biosynthetic Process
Tagcloud ?		aggravating anxa1 banks bedside confidently cons fth1 ftl gliosis immunochemical infarct infarcted infarcts itraq lagging leak malate mdh2 mortem plex pros proteome proteomics putamen shuttle slc25a11 slc25a12 tca vim
Tagcloud (Difference) ?		aggravating anxa1 banks bedside confidently cons fth1 ftl gliosis immunochemical infarct infarcted infarcts itraq lagging leak malate mdh2 mortem plex pros proteome proteomics putamen shuttle slc25a11 slc25a12 tca vim
Tagcloud (Intersection) ?