GNRH1 and GNRHR

Number of citations of the paper that reports this interaction (PMID 9414473)
2

Data Source:
HPRD (in vivo)

		GNRH1	GNRHR
Gene Name		gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)	gonadotropin-releasing hormone receptor
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	Hormone Activity Gonadotropin Hormone-releasing Hormone Activity	Gonadotropin-releasing Hormone Receptor Activity Peptide Binding
	Biological Process	Signal Transduction Cell-cell Signaling Multicellular Organismal Development Female Pregnancy Negative Regulation Of Cell Proliferation Regulation Of Gene Expression Response To Corticosteroid Ovulation Cycle Negative Regulation Of Apoptotic Process Response To Ethanol Regulation Of Ovarian Follicle Development Negative Regulation Of Neuron Migration	G-protein Coupled Receptor Signaling Pathway Multicellular Organismal Development Cellular Response To Gonadotropin-releasing Hormone
Pathways		G alpha (q) signalling events G alpha (q) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Hormone ligand-binding receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding	G alpha (q) signalling events G alpha (q) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Hormone ligand-binding receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs			Leuprolide Goserelin Cetrorelix Abarelix Gonadorelin Nafarelin Danazol Degarelix Buserelin
Diseases
GWAS
Protein-Protein Interactions		2 interactors: GNRHR MEP1A	2 interactors: GNRH1 RGS10
Entrez ID		2796	2798
HPRD ID		08860	00732
Ensembl ID		ENSG00000147437
Uniprot IDs		P01148	P30968
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Gonadotropin-releasing Hormone	Regulation Of Ovarian Follicle Development Regulation Of Female Gonad Development
Tagcloud ?		12h absolutely acting breeding counter darkness daylight exceed gradually happens latitudes naturally net photo photoperiod photoperiods photorefractory prevailing progresses proposes protocols reverses reviews seasons secretion sometimes tandem timing	aas aass abused anabolic androgenic arr19 cyp11a1 cyp17a1 dax1 disturbed enanthate hsd17b4 hsd3b1 hsd3b5 insl3 intramuscular leydig lhcgr milieu oppositely prka prlr1 prlr2 prolactin star steroidogenesis steroidogenic testosterone tspo
Tagcloud (Difference) ?		12h absolutely acting breeding counter darkness daylight exceed gradually happens latitudes naturally net photo photoperiod photoperiods photorefractory prevailing progresses proposes protocols reverses reviews seasons secretion sometimes tandem timing	aas aass abused anabolic androgenic arr19 cyp11a1 cyp17a1 dax1 disturbed enanthate hsd17b4 hsd3b1 hsd3b5 insl3 intramuscular leydig lhcgr milieu oppositely prka prlr1 prlr2 prolactin star steroidogenesis steroidogenic testosterone tspo
Tagcloud (Intersection) ?