COPG2 and PTGES3

Number of citations of the paper that reports this interaction (PMID 11056392)
8

Data Source:
BioGRID (pull down)
HPRD (in vitro, in vivo)

		COPG2	PTGES3
Gene Name		coatomer protein complex, subunit gamma 2	prostaglandin E synthase 3 (cytosolic)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol COPI Vesicle Coat	Chromosome, Telomeric Region Nucleus Nucleoplasm Telomerase Holoenzyme Complex Cytoplasm Cytosol Extracellular Vesicular Exosome
	Molecular Function	Structural Molecule Activity	Telomerase Activity Protein Binding Prostaglandin-E Synthase Activity Unfolded Protein Binding
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport	Telomere Maintenance Prostaglandin Biosynthetic Process RNA-dependent DNA Replication Signal Transduction Arachidonic Acid Metabolic Process Cyclooxygenase Pathway Cellular Response To Heat Small Molecule Metabolic Process Chaperone Cofactor-dependent Protein Refolding Regulation Of Cellular Response To Heat
Pathways			Arachidonic acid metabolism HSF1 activation HSF1-dependent transactivation Metabolism of lipids and lipoproteins Attenuation phase Cellular response to heat stress Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs
Diseases
GWAS			Mean platelet volume ( 22139419) Platelet counts ( 22139419)
Protein-Protein Interactions		11 interactors: ARCN1 ARL1 COPB1 COPE COPG1 COPZ1 COPZ2 DRD1 HES4 PTGES3 TAPBP	25 interactors: AHR AIP ARNT CASP3 CASP7 CAV3 CD2AP COPG1 COPG2 DNAJB1 DNMT3A EIF2AK2 ERBB3 ESR1 FES GZMB HSF1 HSP90AA1 HSPA1A NR3C1 NR3C2 STIP1 SURF1 TERT THRA
Entrez ID		26958	10728
HPRD ID		05074	06138
Ensembl ID			ENSG00000110958
Uniprot IDs		Q9UBF2	Q15185
PDB IDs			1EJF 1LG0
Enriched GO Terms of Interacting Partners?		Retrograde Vesicle-mediated Transport, Golgi To ER COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Golgi Vesicle Transport Localization Within Membrane Vesicle Targeting Membrane Budding Intracellular Transport Establishment Of Localization In Cell Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Vesicle-mediated Transport Cellular Localization Establishment Of Organelle Localization Protein Localization Cellular Protein Localization Protein Transport Organelle Localization Establishment Of Protein Localization Intracellular Protein Transport Intra-Golgi Vesicle-mediated Transport Membrane Organization Transport Organelle Organization Cerebellar Purkinje Cell Layer Maturation Peptide Antigen Stabilization Sensitization Adult Locomotory Behavior Habituation Cerebellum Maturation Nonassociative Learning Adult Behavior Chaperone Cofactor-dependent Protein Refolding Operant Conditioning Establishment Of Golgi Localization Conditioned Taste Aversion Positive Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Cerebral Cortex GABAergic Interneuron Migration Phospholipase C-activating Dopamine Receptor Signaling Pathway Glucose Import Regulation Of Dopamine Uptake Involved In Synaptic Transmission Interneuron Migration From The Subpallium To The Cortex Locomotory Behavior Dopamine Transport Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Cerebral Cortex GABAergic Interneuron Differentiation	Regulation Of Cellular Response To Heat Response To Stimulus Cellular Response To Stimulus Positive Regulation Of Metabolic Process Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Cellular Response To Heat Regulation Of Apoptotic Process Regulation Of Cell Proliferation Protein Refolding Response To Temperature Stimulus Regulation Of Cellular Component Organization Regulation Of Cell Death Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Response To Heat Regulation Of Nitric-oxide Synthase Activity Response To Unfolded Protein Hormone-mediated Signaling Pathway Regulation Of Protein Complex Assembly Transcription From RNA Polymerase II Promoter Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Regulation Of Metabolic Process Regulation Of Immune System Process Signal Transduction Regulation Of Signal Transduction Cellular Response To Organic Cyclic Compound Negative Regulation Of Inclusion Body Assembly Response To Stress Gene Expression Cellular Response To Organic Substance Positive Regulation Of Myeloid Cell Differentiation Regulation Of Oxidoreductase Activity Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C DNA-templated Transcription, Initiation Response To Abiotic Stimulus Positive Regulation Of Microtubule Polymerization Signaling Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Signaling Cell Communication Organelle Organization Negative Regulation Of Cellular Metabolic Process Regulation Of Inclusion Body Assembly Positive Regulation Of Protein Metabolic Process Protein Folding Nucleobase-containing Compound Metabolic Process
Tagcloud ?		allocation ancestor biallelic dimethylation divergence dmr dmrs domestica eutherian eutherians evolved htr2a imprint imprinted imprinting infra intrauterine l3mbtl mest metatherian metatherians monoallelic monodelphis opossum orthologues plagl1 tailed therian therians	12q13 15q25 15q26 3p22 50k beadchip centric cornell customized decile ecg heritability humancvd illumina lvh lyon nmb prognostically qrs rs2290893 rs2292462 rs4966014 rs6797133 scn5a sokolow sum trait typed voltage
Tagcloud (Difference) ?		allocation ancestor biallelic dimethylation divergence dmr dmrs domestica eutherian eutherians evolved htr2a imprint imprinted imprinting infra intrauterine l3mbtl mest metatherian metatherians monoallelic monodelphis opossum orthologues plagl1 tailed therian therians	12q13 15q25 15q26 3p22 50k beadchip centric cornell customized decile ecg heritability humancvd illumina lvh lyon nmb prognostically qrs rs2290893 rs2292462 rs4966014 rs6797133 scn5a sokolow sum trait typed voltage
Tagcloud (Intersection) ?