SH3YL1 and HELZ

Number of citations of the paper that reports this interaction (PMID 12615363)
3

Data Source:
BioGRID (two hybrid)

		SH3YL1	HELZ
Gene Name		SH3 and SYLF domain containing 1	helicase with zinc finger
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Membrane	Nucleus Membrane
	Molecular Function	Phosphatase Binding Phosphatidylinositol Binding	Helicase Activity ATP Binding Poly(A) RNA Binding Metal Ion Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Regulation Of Ruffle Assembly	Metabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: GFAP HELZ KHDRBS1 SH3D19 VIM VPS37B ZBTB7B	4 interactors: GRB2 SH3YL1 SMYD3 STAT5A
Entrez ID		26751	9931
HPRD ID		15336	10452
Ensembl ID		ENSG00000035115	ENSG00000198265
Uniprot IDs		Q96HL8	J3QS41
PDB IDs		2D8H
Enriched GO Terms of Interacting Partners?		Bergmann Glial Cell Differentiation Intermediate Filament Organization Astrocyte Development Intermediate Filament Cytoskeleton Organization Astrocyte Differentiation Intermediate Filament-based Process Positive Regulation Of Schwann Cell Proliferation Glial Cell Development Negative Regulation Of Neuron Projection Development Positive Regulation Of RNA Export From Nucleus Negative Regulation Of Cell Projection Organization Glial Cell Differentiation Negative Regulation Of Neuron Differentiation Gliogenesis Negative Regulation Of Neurogenesis Viral Protein Processing Cytoskeleton Organization Regulation Of RNA Export From Nucleus Negative Regulation Of Cell Development Positive Regulation Of Glial Cell Proliferation Regulation Of Neurotransmitter Uptake Positive Regulation Of Membrane Protein Ectodomain Proteolysis Positive Regulation Of Translational Initiation Regulation Of Neuron Projection Development Lens Fiber Cell Development Virion Assembly Ectoderm Development Regulation Of Cell Projection Organization Intracellular Transport Of Virus	Cellular Response To Hormone Stimulus Positive Regulation Of Mast Cell Differentiation Response To Hormone Positive Regulation Of T Cell Activation Regulation Of Mast Cell Differentiation Development Of Secondary Male Sexual Characteristics Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Negative Regulation Of Mast Cell Apoptotic Process Creatinine Metabolic Process Regulation Of T Cell Activation Regulation Of Mast Cell Apoptotic Process Positive Regulation Of Mast Cell Proliferation Positive Regulation Of Cell Activation Cellular Response To Peptide Hormone Stimulus Isoleucine Metabolic Process Allantoin Metabolic Process Cellular Response To Peptide Taurine Metabolic Process Positive Regulation Of Gamma-delta T Cell Differentiation Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Negative Regulation Of Erythrocyte Differentiation Prolactin Signaling Pathway Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Positive Regulation Of Gamma-delta T Cell Activation Development Of Secondary Female Sexual Characteristics Regulation Of Lymphocyte Activation Valine Metabolic Process Creatine Metabolic Process Branching Involved In Labyrinthine Layer Morphogenesis Positive Regulation Of Natural Killer Cell Differentiation Succinate Metabolic Process Cellular Response To Organic Substance Regulation Of Gamma-delta T Cell Differentiation Development Of Secondary Sexual Characteristics Luteinization Response To Peptide Hormone Positive Regulation Of Interleukin-2 Biosynthetic Process Regulation Of Cell Activation Cellular Response To Organonitrogen Compound Response To Peptide Positive Regulation Of B Cell Differentiation Reproductive Structure Development Reproductive System Development 2-oxoglutarate Metabolic Process Peyer's Patch Development Morphogenesis Of An Epithelium Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Epithelial Cell Differentiation Involved In Prostate Gland Development
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