GDI1 and RAB1B

Number of citations of the paper that reports this interaction (PMID 8836150)
3

Data Source:
HPRD (in vivo)

		GDI1	RAB1B
Gene Name		GDP dissociation inhibitor 1	RAB1B, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Midbody Neuron Projection Protein Complex	Golgi Membrane Mitochondrion Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Pre-autophagosomal Structure Membrane Extracellular Vesicular Exosome
	Molecular Function	GDP-dissociation Inhibitor Activity Rab GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Rab GTPase Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Signal Transduction Small GTPase Mediated Signal Transduction Protein Transport Rab Protein Signal Transduction Positive Regulation Of GTPase Activity Negative Regulation Of Axonogenesis Regulation Of Small GTPase Mediated Signal Transduction Response To Calcium Ion Negative Regulation Of Protein Targeting To Membrane	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Autophagy Virion Assembly Rab Protein Signal Transduction Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Glycoprotein Metabolic Process Regulation Of Autophagic Vacuole Assembly
Pathways		Rho GTPase cycle Signaling by Rho GTPases	Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972)
Protein-Protein Interactions		15 interactors: CDC42 EPB41 GNL1 LNX1 PSEN1 RAB1B RAB27A RAB3B RAB6A RAB9A RABAC1 RAC2 RHOH TK1 UBQLN4	10 interactors: APP CHM GDI1 GOLGA2 MICAL1 MICAL3 MICALCL RUSC2 SMARCC2 TOMM40L
Entrez ID		2664	81876
HPRD ID		02114	11469
Ensembl ID		ENSG00000203879	ENSG00000174903
Uniprot IDs		P31150	E9PLD0 Q9H0U4
PDB IDs			3JZA 3NKV 4HLQ 4I1O
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Small GTPase Mediated Signal Transduction Ras Protein Signal Transduction Intracellular Signal Transduction Peptidyl-cysteine Methylation Vesicle-mediated Transport Single Organismal Cell-cell Adhesion Intracellular Transport Lymphocyte Aggregation Leukocyte Aggregation Leukocyte Cell-cell Adhesion Establishment Of Organelle Localization Homotypic Cell-cell Adhesion Synaptic Vesicle Transport Protein Localization Establishment Of Localization In Cell Cellular Protein Localization Regulation Of Protein Binding Organelle Localization Protein Transport Regulation Of Exocytosis Immune System Process Establishment Of Protein Localization Signal Transduction Intracellular Protein Transport T Cell Mediated Immunity Establishment Of Vesicle Localization Cellular Localization Signaling Vesicle Localization Cell Communication Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Skin Morphogenesis Cell Adhesion Regulation Of Binding Synaptic Vesicle Exocytosis Organelle Transport Along Microtubule Cell Activation T Cell Aggregation T Cell Activation Antigen Processing And Presentation Positive Regulation Of Exocytosis Vesicle Docking Involved In Exocytosis T Cell Activation Involved In Immune Response Positive Regulation Of Constitutive Secretory Pathway Cajal-Retzius Cell Differentiation Beta-amyloid Formation Fetal Process Involved In Parturition Complement-dependent Cytotoxicity	Actin Filament Depolymerization Protein Complex Disassembly Actin Polymerization Or Depolymerization Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Regulation Of Protein Binding Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Protein Targeting To Membrane Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cellular Protein Complex Disassembly Axon Choice Point Recognition Sulfur Oxidation Negative Regulation Of Neuron Differentiation Protein Geranylgeranylation
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