BLOC1S6 and BLOC1S2

Number of citations of the paper that reports this interaction (PMID 15102850)
57

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		BLOC1S6	BLOC1S2
Gene Name		biogenesis of lysosomal organelles complex-1, subunit 6, pallidin	biogenesis of lysosomal organelles complex-1, subunit 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Endosome Cytosol Extrinsic Component Of Membrane Transport Vesicle BLOC-1 Complex SNARE Complex	Gamma-tubulin Complex Nucleus Mitochondrion Centrosome BLOC-1 Complex Recycling Endosome
	Molecular Function	Protein Binding Syntaxin Binding Identical Protein Binding Protein Homodimerization Activity Actin Filament Binding	Protein Binding Protein C-terminus Binding Gamma-tubulin Binding
	Biological Process	Post-Golgi Vesicle-mediated Transport Blood Coagulation Anterograde Axon Cargo Transport Synaptic Vesicle Docking Melanocyte Differentiation Neuron Projection Development Melanosome Transport Melanosome Organization Positive Regulation Of Natural Killer Cell Activation Secretion Of Lysosomal Enzymes Endosome To Melanosome Transport Anterograde Synaptic Vesicle Transport Positive Regulation Of Pigment Cell Differentiation Membrane Organization Membrane Fusion	Microtubule Nucleation Anterograde Axon Cargo Transport Positive Regulation Of Cell Proliferation Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Neuron Projection Development Melanosome Organization Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Mitochondrial Outer Membrane Permeabilization
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		38 interactors: ABI2 AGGF1 ANK1 APP BLOC1S1 BLOC1S2 BLOC1S4 CCDC136 CCDC22 CCDC53 CCHCR1 CDK5R1 CORO6 DCTN2 DTNBP1 EPS8 EXOC8 HAUS1 IFT20 KRT13 LURAP1 MED21 NDC80 NDN NUP62 OLFM2 PLEKHA5 PLEKHF2 RABGEF1 SKA1 SLC4A1 SMN2 SNAPIN STX11 STX12 SYCE3 TPM3 WDYHV1	15 interactors: APP BLOC1S1 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 C8orf33 FAM9B HMOX2 MEST PAM16 RDH11 SNAPIN TNNT1 WASH1
Entrez ID		26258	282991
HPRD ID		16055	12526
Ensembl ID		ENSG00000104164
Uniprot IDs		B3KY40 Q9UL45	F1T0F0 Q6QNY1
PDB IDs
Enriched GO Terms of Interacting Partners?		Anterograde Synaptic Vesicle Transport Establishment Of Localization In Cell Axon Cargo Transport Melanosome Organization Pigment Granule Organization Organelle Organization Cellular Pigmentation Anterograde Axon Cargo Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Localization Organelle Localization Synaptic Vesicle Transport Movement Of Cell Or Subcellular Component Establishment Of Vesicle Localization Intracellular Transport Pigmentation Vesicle Organization Establishment Of Organelle Localization Vesicle Localization Membrane Organization Neuron Development Microtubule-based Process Neuron Projection Development Platelet Dense Granule Organization Microtubule-based Movement Cytoskeleton Organization Neuron Differentiation Cell Projection Organization Vesicle-mediated Transport Protein Localization Protein Transport Establishment Of Protein Localization Cell Development Post-Golgi Vesicle-mediated Transport Generation Of Neurons Cellular Protein Localization Neurogenesis Neuron Recognition Secretory Granule Organization Transport Endomembrane System Organization Golgi Vesicle Transport Vesicle Fusion Nervous System Development Mitotic Nuclear Division Secretion By Cell Synaptic Vesicle Fusion To Presynaptic Membrane Exocytosis Organelle Fusion	Anterograde Synaptic Vesicle Transport Axon Cargo Transport Melanosome Organization Pigment Granule Organization Anterograde Axon Cargo Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Pigmentation Synaptic Vesicle Transport Pigmentation Microtubule-based Movement Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Pigment Granule Maturation Endosome To Melanosome Transport Establishment Of Organelle Localization Intracellular Transport Cellular Pigment Accumulation Organelle Localization Microtubule-based Process Endosomal Transport Neuron Projection Development Establishment Of Localization In Cell Post-Golgi Vesicle-mediated Transport Vesicle-mediated Transport Movement Of Cell Or Subcellular Component Neuron Development Synaptic Transmission Cellular Localization Neuron Differentiation Cell Projection Organization Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Secretion Of Lysosomal Enzymes Cell-cell Signaling Secretion By Cell Developmental Pigmentation Generation Of Neurons Neurogenesis Golgi Vesicle Transport Platelet Dense Granule Organization Secretion Cell Development Positive Regulation Of Pigment Cell Differentiation Cytoplasmic Transport Transport Exocytosis
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