POLDIP2 and REV1

Number of citations of the paper that reports this interaction (PMID 20554254)
7

Data Source:
BioGRID (two hybrid)

		POLDIP2	REV1
Gene Name		polymerase (DNA-directed), delta interacting protein 2	REV1, polymerase (DNA directed)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Nucleoid	Nucleoplasm
	Molecular Function	DNA Binding	Magnesium Ion Binding Damaged DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Deoxycytidyl Transferase Activity
	Biological Process	Mitochondrion Morphogenesis	DNA Replication DNA Repair Response To UV Error-prone Translesion Synthesis
Pathways			DNA Damage Bypass Translesion synthesis by DNA polymerases bypassing lesion on DNA template Translesion synthesis by HREV1
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972)
Protein-Protein Interactions		14 interactors: ALAS1 APP ASCC2 CPE HDAC6 MAD2L2 MTUS2 PCNA PDPK1 POLD2 POLN REV1 SELENBP1 TAB1	8 interactors: FHL2 MAD2L2 POLDIP2 POLH POLI POLK POLL REV3L
Entrez ID		26073	51455
HPRD ID		17874	16202
Ensembl ID		ENSG00000004142	ENSG00000135945
Uniprot IDs		Q9Y2S7	Q9UBZ9
PDB IDs			2EBW 2LSI 2LSK 2LSY 3GQC 3VU7 4BA9 4EXT 4GK0 4GK5
Enriched GO Terms of Interacting Partners?		Translesion Synthesis Postreplication Repair DNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Cellular Response To Stress Nitrogen Compound Metabolic Process DNA Repair DNA Replication Response To Stress Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA-dependent DNA Replication Nucleotide-excision Repair, DNA Gap Filling Telomere Maintenance Via Semi-conservative Replication Cellular Response To DNA Damage Stimulus Nuclear DNA Replication Telomere Maintenance Via Recombination Mitotic Recombination DNA Strand Elongation Involved In DNA Replication Nucleobase-containing Compound Metabolic Process DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening DNA Metabolic Process Cellular Macromolecule Biosynthetic Process Biosynthetic Process Macromolecule Biosynthetic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Transcription-coupled Nucleotide-excision Repair DNA Recombination Cellular Metabolic Process Cellular Response To Stimulus Mismatch Repair Base-excision Repair Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Positive Regulation Of Deoxyribonuclease Activity Hsp90 Deacetylation Negative Regulation Of Catalytic Activity Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Proteolysis Telomere Maintenance Regulation Of Catalytic Activity Negative Regulation Of Protein Processing Negative Regulation Of Protein Metabolic Process Positive Regulation Of Chaperone-mediated Protein Complex Assembly Leading Strand Elongation Synaptic Growth At Neuromuscular Junction Polyubiquitinated Misfolded Protein Transport Nucleotide-excision Repair Regulation Of Protein Processing Positive Regulation Of Cellular Metabolic Process	DNA Biosynthetic Process DNA Repair DNA Replication Cellular Response To DNA Damage Stimulus DNA Metabolic Process Cellular Response To Stress Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Postreplication Repair Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Response To Stress Nitrogen Compound Metabolic Process Nucleotide-excision Repair DNA-dependent DNA Replication Cellular Response To Stimulus Atrial Cardiac Muscle Cell Development Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Error-prone Translesion Synthesis Negative Regulation Of APC-Cdc20 Complex Activity Negative Regulation Of Transcription By Competitive Promoter Binding Response To Stimulus Translesion Synthesis Response To UV-C Pyrimidine Dimer Repair DNA Damage Response, Signal Transduction Resulting In Transcription Somatic Hypermutation Of Immunoglobulin Genes Heart Trabecula Formation DNA Synthesis Involved In DNA Repair Negative Regulation Of Transcription Regulatory Region DNA Binding Somatic Diversification Of Immune Receptors Via Somatic Mutation Nucleotide-excision Repair, DNA Gap Filling Ventricular Cardiac Muscle Cell Development Negative Regulation Of Epithelial To Mesenchymal Transition Regulation Of Transcription Regulatory Region DNA Binding Mitochondrion Morphogenesis Heart Trabecula Morphogenesis Ventricular Cardiac Muscle Cell Differentiation
Tagcloud ?		atherosclerosis cdk1 curves cyclina2 delta die doubling e2f elongation embryos heterozygous homozygous lc3b mefs nox4 originally p21cip1 partner passage pcna proliferating restenosis s20 sirt1 sv40 transfection unaffected underline understudied	augment consequent delaying elusive emerged enhance enhancing facilitates fasting fate linking maintenance melanoma modifications modified node nutrient partner promising relief sensing short specialized starvation sumo2 suppressor therapies toxic turn
Tagcloud (Difference) ?		atherosclerosis cdk1 curves cyclina2 delta die doubling e2f elongation embryos heterozygous homozygous lc3b mefs nox4 originally p21cip1 passage pcna proliferating restenosis s20 sirt1 sv40 transfection unaffected underline understudied	augment consequent delaying elusive emerged enhance enhancing facilitates fasting fate linking maintenance melanoma modifications modified node nutrient promising relief sensing short specialized starvation sumo2 suppressor therapies toxic turn
Tagcloud (Intersection) ?		partner