CNTNAP2 and ZMIZ1

Number of citations of the paper that reports this interaction (PMID 12421765)
28

Data Source:
HPRD (two hybrid)

		CNTNAP2	ZMIZ1
Gene Name		contactin associated protein-like 2	zinc finger, MIZ-type containing 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Early Endosome Golgi Apparatus Voltage-gated Potassium Channel Complex Cell Surface Membrane Integral Component Of Membrane Axon Dendrite Axolemma Neuronal Cell Body Perikaryon Juxtaparanode Region Of Axon	Nucleoplasm Cytoplasm Nuclear Speck Intracellular Membrane-bounded Organelle
	Molecular Function	Enzyme Binding	Zinc Ion Binding
	Biological Process	Cell Adhesion Brain Development Learning Neuron Recognition Transmission Of Nerve Impulse Striatum Development Limbic System Development Thalamus Development Cerebral Cortex Development Adult Behavior Neuron Projection Development Cellular Protein Localization Social Behavior Clustering Of Voltage-gated Potassium Channels Superior Temporal Gyrus Development Protein Localization To Juxtaparanode Region Of Axon Vocalization Behavior	Vasculogenesis In Utero Embryonic Development Heart Morphogenesis Transcription, DNA-templated Vitellogenesis Cell Aging Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Fibroblast Proliferation Developmental Growth Artery Morphogenesis
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease ( 22159054) Bipolar disorder and schizophrenia ( 20889312) Body mass index (interaction) ( 23192594) Bone mineral density ( 17903296) Obesity-related traits ( 23251661) QT interval (interaction) ( 23459443) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Breast cancer ( 23535729 20453838) Celiac disease ( 20190752) Crohn's disease ( 21102463) Crohn's disease and psoriasis ( 22482804) Height ( 23563607) Inflammatory bowel disease (early onset) ( 19915574) Multiple sclerosis ( 22190364 19525953 21833088) Vitiligo ( 20526339)
Protein-Protein Interactions		8 interactors: CASK CNTN2 CTR9 EPB41L3 KCNA2 MACF1 MEOX2 ZMIZ1	5 interactors: AR CACHD1 CNTNAP2 PIAS3 TBC1D4
Entrez ID		26047	57178
HPRD ID		05197	12115
Ensembl ID		ENSG00000174469	ENSG00000108175
Uniprot IDs		B2RCH4 Q9UHC6	A0JLS3 Q9ULJ6
PDB IDs
Enriched GO Terms of Interacting Partners?		Anatomical Structure Morphogenesis Protein Localization To Juxtaparanode Region Of Axon Multicellular Organismal Development Anatomical Structure Development Developmental Process System Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Formation Involved In Morphogenesis Embryo Development Establishment Of Protein Localization To Juxtaparanode Region Of Axon Regulation Of Cell Morphogenesis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Adenosine Receptor Signaling Pathway Optic Nerve Structural Organization Vitellogenesis Positive Regulation Of Histone H3-K79 Methylation Regulation Of Cell-matrix Adhesion Formation Of Primary Germ Layer Positive Regulation Of Macromolecule Biosynthetic Process Clustering Of Voltage-gated Potassium Channels Positive Regulation Of Gene Expression Myelination Protein Localization To Plasma Membrane Axon Ensheathment Positive Regulation Of Cellular Biosynthetic Process Regulation Of Axonogenesis Gastrulation Regulation Of Cell-substrate Adhesion Protein Localization To Paranode Region Of Axon Somite Specification Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Axon Diameter Membrane Organization Plasma Membrane Organization Cell Differentiation Regulation Of Cellular Component Organization Positive Regulation Of Metabolic Process Posttranslational Protein Targeting To Membrane Cytoplasm Organization Cerebral Cortex GABAergic Interneuron Migration Histone H2B Ubiquitination Regulation Of Cell Projection Size Interneuron Migration From The Subpallium To The Cortex Optic Nerve Morphogenesis Presynaptic Membrane Organization Wnt Signaling Pathway Cytoskeletal Anchoring At Plasma Membrane Negative Regulation Of Keratinocyte Proliferation Neuronal Ion Channel Clustering Paranodal Junction Assembly	Negative Regulation Of Integrin Biosynthetic Process Superior Temporal Gyrus Development Response To Hormone Clustering Of Voltage-gated Potassium Channels Positive Regulation Of Integrin Biosynthetic Process Regulation Of Integrin Biosynthetic Process Negative Regulation Of Vesicle Fusion Positive Regulation Of Transcription From RNA Polymerase III Promoter Protein Localization To Juxtaparanode Region Of Axon Neuronal Ion Channel Clustering Positive Regulation Of Protein Sumoylation Thalamus Development Vocalization Behavior Striatum Development
Tagcloud ?		acutely ameliorate asd autism cdfe contactin deficit deficits designer displays dreadd dysregulation epilepsy exclusively homolog hypothalamus immunoreactive knockout lasting melanocortin neuropeptide neuropsychiatric oxytocin paraventricular penetrance pvn rectify rescued windows	10q22 11q13 16p13 17q21 19p13 22q11 9p24 crohn enlarge epidemiologically exonic fut2 il12b il23r near pathologically prdx5 ps refinement rel rs1250544 rs181359 rs4780355 rs694739 shared socs1 therapeutically tyk2 ydjc
Tagcloud (Difference) ?		acutely ameliorate asd autism cdfe contactin deficit deficits designer displays dreadd dysregulation epilepsy exclusively homolog hypothalamus immunoreactive knockout lasting melanocortin neuropeptide neuropsychiatric oxytocin paraventricular penetrance pvn rectify rescued windows	10q22 11q13 16p13 17q21 19p13 22q11 9p24 crohn enlarge epidemiologically exonic fut2 il12b il23r near pathologically prdx5 ps refinement rel rs1250544 rs181359 rs4780355 rs694739 shared socs1 therapeutically tyk2 ydjc
Tagcloud (Intersection) ?