RNF19A and SNCAIP

Number of citations of the paper that reports this interaction (PMID 12750386)
9

Data Source:
HPRD (in vitro)

		RNF19A	SNCAIP
Gene Name		ring finger protein 19A, RBR E3 ubiquitin protein ligase	synuclein, alpha interacting protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Integral Component Of Membrane	Cytoplasm Synaptic Vesicle Presynaptic Membrane Neuronal Cell Body
	Molecular Function	Transcription Factor Binding Zinc Ion Binding Ligase Activity	Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Protein Ubiquitination	Dopamine Metabolic Process Regulation Of Neurotransmitter Secretion Regulation Of Inclusion Body Assembly
Pathways
Drugs
Diseases
GWAS		Atrioventricular conduction ( 21041692)
Protein-Protein Interactions		16 interactors: C11orf58 CASR ILK MAP3K7 NUDT21 RPS6KA5 SNCAIP SOD1 SUFU TUBG1 TUBG2 UBE2E2 UBE2L3 UBE2L6 VCP ZAK	19 interactors: AES AGXT C11orf58 GET4 GSK3B NUB1 NUDT21 PARK2 PINK1 PPHLN1 PPP1CA PTN RNF19A SEPT4 SH2D3C SIAH1 SIAH2 SNCA UBB
Entrez ID		25897	9627
HPRD ID		06176	04804
Ensembl ID		ENSG00000034677	ENSG00000064692
Uniprot IDs		Q9NV58	Q9NVG1 Q9Y6H5
PDB IDs			2KES
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Modification Process Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Cellular Protein Metabolic Process ISG15-protein Conjugation Positive Regulation Of Protein Metabolic Process Positive Regulation Of MAP Kinase Activity MAPK Cascade Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Transferase Activity JNK Cascade Cellular Response To Stress Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Catalytic Activity Signal Transduction By Phosphorylation Regulation Of Protein Metabolic Process Regulation Of MAP Kinase Activity Positive Regulation Of Protein Phosphorylation Microtubule Nucleation Epithelial Tube Morphogenesis Protein K11-linked Ubiquitination Cellular Response To Organic Substance Activation Of MAPK Activity Response To Stress Microtubule Polymerization Tube Morphogenesis Positive Regulation Of MAPK Cascade Positive Regulation Of Phosphorylation Positive Regulation Of Protein Kinase Activity Vasodilation Positive Regulation Of Kinase Activity Cytoplasmic Microtubule Organization Morphogenesis Of An Epithelium Microtubule Polymerization Or Depolymerization Regulation Of Cytokine Production Protein Complex Assembly Cell Cycle Process Myelination In Peripheral Nervous System Regulation Of Catalytic Activity Protein Ubiquitination Cellular Protein Modification Process Regulation Of Protein Phosphorylation Schwann Cell Development Epithelium Development Toll-like Receptor 5 Signaling Pathway Protein Modification By Small Protein Conjugation Toll-like Receptor 10 Signaling Pathway Regulation Of MAPK Cascade Cell Cycle Phase Transition Response To Organic Substance	Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Apoptotic Process Regulation Of Cell Death Positive Regulation Of Proteolysis Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Protein Ubiquitination Regulation Of Proteolysis Regulation Of Dopamine Secretion Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Regulation Of Signal Transduction Ubiquitin-dependent Protein Catabolic Process Dopamine Uptake Involved In Synaptic Transmission Modification-dependent Protein Catabolic Process Positive Regulation Of Signal Transduction Energy Derivation By Oxidation Of Organic Compounds Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Positive Regulation Of Protein Ubiquitination Regulation Of Protein Stability Regulation Of Synaptic Vesicle Transport Regulation Of Signaling Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Carbohydrate Metabolic Process Regulation Of Cellular Response To Oxidative Stress Positive Regulation Of Mitochondrion Organization Positive Regulation Of Cellular Protein Metabolic Process Generation Of Precursor Metabolites And Energy Glycogen Metabolic Process Negative Regulation Of Wnt Signaling Pathway Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Oxidative Stress-induced Neuron Death Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Catalytic Activity Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Protein Metabolic Process
Tagcloud ?			adar colorectal contain dcaf12l2 exomes glt1d1 hot instability itga7 map1b microsatellite mrgprx4 oncogenes personalized profiling psrc1 ranbp2 respective rps6kl1 sequenced spot spots tceal6 tubb6 validated validation vegfb wbp5 zbtb2
Tagcloud (Difference) ?			adar colorectal contain dcaf12l2 exomes glt1d1 hot instability itga7 map1b microsatellite mrgprx4 oncogenes personalized profiling psrc1 ranbp2 respective rps6kl1 sequenced spot spots tceal6 tubb6 validated validation vegfb wbp5 zbtb2
Tagcloud (Intersection) ?