ASF1A and HTATIP2

Number of citations of the paper that reports this interaction (PMID 15073177)
13

Data Source:
BioGRID (pull down)

		ASF1A	HTATIP2
Gene Name		anti-silencing function 1A histone chaperone	HIV-1 Tat interactive protein 2, 30kDa
Image
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Protein Complex	Nucleus Nuclear Envelope Cytoplasm Membrane
	Molecular Function	Chromatin Binding Protein Binding Histone Binding	Transcription Coactivator Activity Protein Binding Oxidoreductase Activity
	Biological Process	Osteoblast Differentiation DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Transcription, DNA-templated Chromatin Modification Negative Regulation Of Chromatin Silencing Muscle Cell Differentiation	Angiogenesis Regulation Of Transcription From RNA Polymerase II Promoter Apoptotic Process Viral Process Cell Differentiation Negative Regulation Of Apoptotic Process Regulation Of Angiogenesis Nuclear Import Oxidation-reduction Process
Pathways		DNA Damage/Telomere Stress Induced Senescence Formation of Senescence-Associated Heterochromatin Foci (SAHF) Cellular Senescence
Drugs
Diseases
GWAS		QT interval ( 19305408)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		22 interactors: ASF1B CDAN1 CHAF1A CHAF1B CHEK2 H3F3A HIRA HIST1H3C HIST1H3E HIST1H4F HIST1H4L HIST3H3 HIST4H4 HTATIP2 PAFAH1B2 PRR3 ST13 TAF1 TLK1 TLK2 VPS28 ZDHHC17	3 interactors: ASF1A ETS1 NCOA5
Entrez ID		25842	10553
HPRD ID		16459	09288
Ensembl ID		ENSG00000111875	ENSG00000109854
Uniprot IDs		Q9Y294	Q9BUP3
PDB IDs		1TEY 2I32 2IIJ 2IO5 3AAD	2BKA
Enriched GO Terms of Interacting Partners?		DNA Replication-dependent Nucleosome Assembly Chromatin Assembly Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly DNA Packaging Nucleosome Assembly Nucleosome Organization Chromatin Organization DNA Conformation Change Chromosome Organization DNA Methylation On Cytosine Chromatin Silencing At RDNA DNA Replication-independent Nucleosome Assembly Chromatin Silencing Cellular Macromolecular Complex Assembly Cellular Component Assembly Protein Complex Assembly DNA Methylation Negative Regulation Of Gene Expression, Epigenetic DNA Modification Organelle Organization Gene Silencing Histone H4-K20 Demethylation DNA Metabolic Process Negative Regulation Of Megakaryocyte Differentiation Regulation Of Gene Expression, Epigenetic Chromatin Modification Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Telomere Maintenance Regulation Of Megakaryocyte Differentiation Negative Regulation Of Biosynthetic Process Cell Cycle Regulation Of Metabolic Process Gene Expression Methylation CENP-A Containing Nucleosome Assembly Regulation Of Hematopoietic Progenitor Cell Differentiation Histone Exchange Histone Lysine Demethylation Histone Demethylation Protein Demethylation Regulation Of Chromatin Assembly Or Disassembly Centromere Complex Assembly Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Demethylation	PML Body Organization Negative Regulation Of Chromatin Silencing Transcription, DNA-templated RNA Biosynthetic Process DNA Replication-dependent Nucleosome Assembly Response To Laminar Fluid Shear Stress Positive Regulation Of Gene Expression, Epigenetic Angiogenesis Involved In Wound Healing RNA Metabolic Process Positive Regulation Of Erythrocyte Differentiation Regulation Of Gene Silencing Hypothalamus Development Gene Expression Cellular Macromolecule Biosynthetic Process Regulation Of Extracellular Matrix Disassembly Macromolecule Biosynthetic Process DNA Replication-independent Nucleosome Assembly Response To Fluid Shear Stress Regulation Of Erythrocyte Differentiation Negative Regulation Of Insulin Receptor Signaling Pathway Regulation Of Extracellular Matrix Organization Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Pituitary Gland Development Positive Regulation Of Endothelial Cell Migration Nucleobase-containing Compound Metabolic Process Cellular Response To Hydrogen Peroxide Response To Antibiotic Regulation Of Insulin Receptor Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Myeloid Cell Differentiation Regulation Of Cellular Response To Insulin Stimulus Positive Regulation Of Epithelial Cell Migration Response To Interleukin-1 Diencephalon Development Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Stress Positive Regulation Of Gene Expression Limbic System Development Cellular Response To Reactive Oxygen Species Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process
Tagcloud ?		assembled caf chaperone chaperones dissect divergent enhances experiencing h4 hira histones involves mimetic newly nucleosomes organization phospho phosphorylated pocket restore shuttle stimulating supply tail timely tlk tlks tousled
Tagcloud (Difference) ?		assembled caf chaperone chaperones dissect divergent enhances experiencing h4 hira histones involves mimetic newly nucleosomes organization phospho phosphorylated pocket restore shuttle stimulating supply tail timely tlk tlks tousled
Tagcloud (Intersection) ?