GABARAPL1 and TBC1D7

Number of citations of the paper that reports this interaction (PMID 22354992)
16

Data Source:
BioGRID (affinity chromatography technology, pull down)

		GABARAPL1	TBC1D7
Gene Name		GABA(A) receptor-associated protein like 1	TBC1 domain family, member 7
Image
Gene Ontology Annotations	Cellular Component	Pre-autophagosomal Structure Autophagic Vacuole Membrane Intracellular Autophagic Vacuole Endoplasmic Reticulum Golgi Apparatus Cytosol Microtubule Extrinsic Component Of Membrane Cytoplasmic Vesicle Membrane Dendrite Membrane Dendrite Cytoplasm Cell Body	Cytoplasmic Membrane-bounded Vesicle Cytoplasmic Vesicle Ciliary Basal Body
	Molecular Function	Protein Binding Microtubule Binding Tat Protein Binding Beta-tubulin Binding GABA Receptor Binding	Rab GTPase Activator Activity Protein Binding Rab GTPase Binding
	Biological Process	Autophagic Vacuole Assembly Mitochondrion Degradation Nucleophagy Membrane Fusion	Positive Regulation Of Protein Ubiquitination Negative Regulation Of TOR Signaling Positive Regulation Of Rab GTPase Activity Activation Of Rho GTPase Activity Response To Growth Factor Negative Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		35 interactors: AHNAK2 ATG4A ATG4B ATG4D CALCOCO2 DVL2 FAM134C FUNDC1 KBTBD7 KRTAP10-3 KRTAP10-7 KRTAP10-9 MAPK15 OPRK1 RABGAP1 RABGAP1L SCYL3 SNCA SQSTM1 SRPK1 SRPK2 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 VDR	16 interactors: APP BLZF1 GABARAPL1 HOOK1 IKBKG KRT19 LDOC1 LZTS2 MAP1LC3A NEDD4 NEDD4L RPGRIP1 SSNA1 TRAF4 TSC1 TSC2
Entrez ID		23710	51256
HPRD ID		07601	18165
Ensembl ID		ENSG00000139112	ENSG00000145979
Uniprot IDs		Q9H0R8	Q5JPB9 Q9P0N9
PDB IDs		2L8J 2R2Q	3QWL
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Positive Regulation Of Ras GTPase Activity Regulation Of Ras Protein Signal Transduction Regulation Of Ras GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Positive Regulation Of Catalytic Activity Positive Regulation Of Metabolic Process Regulation Of Intracellular Signal Transduction Autophagy Regulation Of Catalytic Activity Regulation Of Signal Transduction Regulation Of Signaling Protein Delipidation Mitochondrion Degradation Organelle Disassembly Regulation Of Metabolic Process Macroautophagy Cellular Response To Nitrogen Starvation Retrograde Transport, Endosome To Golgi Cellular Response To Nutrient Levels Nucleophagy Response To Starvation C-terminal Protein Lipidation Endosomal Transport Cellular Response To Extracellular Stimulus Protein Processing Response To Nutrient Levels Positive Regulation Of Autophagy Response To Extracellular Stimulus Autophagic Vacuole Assembly Cellular Response To Starvation Negative Regulation Of Viral Genome Replication Regulation Of Viral Genome Replication Mitochondrion Organization Negative Regulation Of Viral Process Vacuole Organization Regulation Of Autophagy Positive Regulation Of Viral Genome Replication Protein Lipidation Intracellular Transport Lipoprotein Biosynthetic Process Cellular Localization Response To Stress Establishment Of Localization In Cell Positive Regulation Of Protein Metabolic Process	Establishment Of Localization In Cell Intracellular Transport Cytoplasmic Transport Cellular Localization Glucose Import Negative Regulation Of Sodium Ion Transport Vacuole Organization Negative Regulation Of Signal Transduction Negative Regulation Of Cell Size Negative Regulation Of Signaling Activation Of NF-kappaB-inducing Kinase Activity Regulation Of Protein Kinase Activity Nucleophagy Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cellular Component Assembly Regulation Of Kinase Activity Positive Regulation Of NIK/NF-kappaB Signaling Regulation Of Potassium Ion Transmembrane Transporter Activity Response To Stimulus Mitochondrion Degradation Regulation Of Signal Transduction Negative Regulation Of TOR Signaling Membrane Organization Cell Communication Synapse Organization NIK/NF-kappaB Signaling Regulation Of NIK/NF-kappaB Signaling Organelle Assembly Regulation Of Protein Metabolic Process Organ Development Regulation Of Potassium Ion Transmembrane Transport Intracellular Receptor Signaling Pathway Organelle Disassembly Negative Regulation Of Insulin Receptor Signaling Pathway Protein Monoubiquitination Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Signaling Autophagic Vacuole Assembly Viral Process Cell Surface Receptor Signaling Pathway Lysosomal Transport Regulation Of Protein Phosphorylation Neuromuscular Junction Development Regulation Of TOR Signaling Macroautophagy Nucleocytoplasmic Transport Nuclear Transport Regulation Of Cell Junction Assembly Cellular Response To Stimulus Cell Projection Organization
Tagcloud ?		2000mug 3f aminobutyric anabolism atg12 atg13 atg5 atrogin atrogin1 autophagosome beta2 bnip3 culminated e1b eb eif3 formoterol hydrolases kinase1 lc3b mafbx myod protein3 relativized sqstm1 tfeb tibialis ulk1 unc	2a akt anabolic bub2 cdc16 coimmunoprecipitated constant dephosphorylation homolog mechanistic modulator mtorc1 nutrients phosphorylates pp2a rapamycin redd1 repress represses repressor rheb ser stimulating thr tre2 tsc tsc1 tsc2 tuberous
Tagcloud (Difference) ?		2000mug 3f aminobutyric anabolism atg12 atg13 atg5 atrogin atrogin1 autophagosome beta2 bnip3 culminated e1b eb eif3 formoterol hydrolases kinase1 lc3b mafbx myod protein3 relativized sqstm1 tfeb tibialis ulk1 unc	2a akt anabolic bub2 cdc16 coimmunoprecipitated constant dephosphorylation homolog mechanistic modulator mtorc1 nutrients phosphorylates pp2a rapamycin redd1 repress represses repressor rheb ser stimulating thr tre2 tsc tsc1 tsc2 tuberous
Tagcloud (Intersection) ?