CADM1 and EPB41L3

Number of citations of the paper that reports this interaction (PMID 12234973)
31

Data Source:
HPRD (in vivo, in vitro)

		CADM1	EPB41L3
Gene Name		cell adhesion molecule 1	erythrocyte membrane protein band 4.1-like 3
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Synaptic Vesicle Integral Component Of Membrane Basolateral Plasma Membrane Axon Dendrite Extracellular Vesicular Exosome	Cytoplasm Cytoskeleton Plasma Membrane Cell-cell Junction Extrinsic Component Of Membrane Axolemma Paranode Region Of Axon Juxtaparanode Region Of Axon
	Molecular Function	Receptor Binding Protein Binding PDZ Domain Binding Protein Homodimerization Activity Cell Adhesion Molecule Binding	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding
	Biological Process	Liver Development T Cell Mediated Cytotoxicity Apoptotic Process Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Spermatogenesis Synapse Assembly Brain Development Cell Recognition Unidimensional Cell Growth Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Cell Differentiation Cell Junction Assembly Adherens Junction Organization Susceptibility To Natural Killer Cell Mediated Cytotoxicity Cell-cell Junction Organization Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Cytokine Secretion Activated T Cell Proliferation Detection Of Stimulus Bone Development	Protein Localization To Paranode Region Of Axon Apoptotic Process Cytoskeletal Anchoring At Plasma Membrane Biological_process Regulation Of Cell Shape Cortical Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Paranodal Junction Assembly Myelin Maintenance Neuron Projection Morphogenesis Protein Localization To Juxtaparanode Region Of Axon Protein Localization To Plasma Membrane
Pathways		Nectin/Necl trans heterodimerization Cell junction organization Cell-cell junction organization Adherens junctions interactions
Drugs
Diseases
GWAS		Cardiovascular disease risk factors ( 20838585) Obesity-related traits ( 23251661)
Protein-Protein Interactions		6 interactors: ATF7IP CASK EPB41L3 MPP3 PSMA6 SDCBP	17 interactors: ATXN1L CADM1 CEP152 CLNS1A CNTNAP2 IGSF21 MBIP PAXIP1 PSEN1 SPTBN1 TCF4 UNC13A YWHAB YWHAG YWHAH YWHAQ YWHAZ
Entrez ID		23705	23136
HPRD ID		05746	05622
Ensembl ID		ENSG00000182985	ENSG00000082397
Uniprot IDs		A0A4Z1 Q9BY67	A8K968 B7Z4I5 F5GX05 Q9Y2J2
PDB IDs		3BIN 4H5S	2HE7 3BIN
Enriched GO Terms of Interacting Partners?		Nucleotide Phosphorylation	Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Positive Regulation Of Intracellular Transport Positive Regulation Of Transport Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Cellular Localization Intrinsic Apoptotic Signaling Pathway Regulation Of Establishment Of Protein Localization Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Organelle Organization Protein Targeting Regulation Of Intracellular Transport Nervous System Development Regulation Of Protein Localization Cellular Localization Membrane Organization System Development Cellular Protein Localization Protein Localization Intracellular Protein Transport Regulation Of Organelle Organization Regulation Of Cellular Component Organization Protein Transport Establishment Of Localization In Cell Apoptotic Process Establishment Of Protein Localization Programmed Cell Death Intracellular Transport Apoptotic Signaling Pathway Cell Death Death Multicellular Organismal Development Regulation Of Synaptic Plasticity Anatomical Structure Development Brain Development Head Development Positive Regulation Of Signal Transduction Intracellular Signal Transduction Cellular Component Assembly Developmental Process Regulation Of Apoptotic Process Central Nervous System Development Regulation Of Cell Death Generation Of Neurons Regulation Of Synaptic Transmission
Tagcloud ?		125b acvr1b acvr2a arid3b bak1 bcl2l2 bear bim bmpr1b cardio cardiology cmass e2f3 fgfr2 fgfr3 glut3 il6r jph2 men1 mirs onco orchestration raf1 sitr7 smoothened st7l twist1 wee1 wnt7a
Tagcloud (Difference) ?		125b acvr1b acvr2a arid3b bak1 bcl2l2 bear bim bmpr1b cardio cardiology cmass e2f3 fgfr2 fgfr3 glut3 il6r jph2 men1 mirs onco orchestration raf1 sitr7 smoothened st7l twist1 wee1 wnt7a
Tagcloud (Intersection) ?