TNIK and SOS1

  • Number of citations of the paper that reports this interaction (PMID 17043677)
  • 96
  • Data Source:
  • BioGRID (two hybrid)

TNIK

SOS1

Gene Name TRAF2 and NCK interacting kinase son of sevenless homolog 1 (Drosophila)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Brain imaging in schizophrenia (interaction) ( 19023125)
  • Coronary heart disease ( 21347282)
Protein-Protein Interactions 38 interactors: ACTG1 AGTPBP1 AKAP9 ANK2 CLU CNKSR2 DISC1 DPYSL2 DPYSL3 DST DYNC1H1 GOLGA4 GSE1 GSN HARS MACF1 NCK1 NCOR2 NEDD4 NEFM PAFAH1B1 PDE4DIP PPM1E PPP1R13B RAP2A SLC9A1 SMARCE1 SNX6 SOS1 SPTBN1 SRGAP3 SYNE1 TIAM2 TNKS TRAF2 TRIM2 TUBB2A WWC1 52 interactors: ABI1 ABI3 ANXA2 ATP6V1E1 BIN1 CAV1 CD19 CD2AP CRK CRKL CSF1R EGFR EPS8 EPS8L1 EPS8L2 ERBB2 ERBB3 ESR1 FGFR1 FRS2 FYN GAB1 GRAP GRB2 HCK HDLBP HRAS ITSN1 ITSN2 LAT2 LCK MAPK1 MUC1 NCK1 NCK2 PACSIN1 PACSIN3 PIK3R2 PLCG1 PTPN11 PTPN6 RANBP9 RIT2 RRAS SH3BP5 SH3KBP1 SHC1 SNX18 SNX9 SPTAN1 TNIK ZAP70
Entrez ID 23043 6654
HPRD ID 18206 01681
Ensembl ID ENSG00000154310 ENSG00000115904
Uniprot IDs Q9UKE5 G5E9C8 Q07889
PDB IDs 2X7F 1AWE 1BKD 1DBH 1NVU 1NVV 1NVW 1NVX 1Q9C 1XD2 1XD4 1XDV 2II0 3KSY
Enriched GO Terms of Interacting Partners?
Tagcloud ?
a549  attenuation  carboxamide  competition  continuing  crosstalk  docking  efforts  emerging  emt  fak  focal  hinge  ky  methylbenzamido  motility  nck  orchestrated  paxillin  pharmacologic  phenylamino  smad  tgf  thiazole  traf2  transforming  triggers  validate  wnt 
accordingly  antisense  b9  cascade  cascades  distal  gp130  il  independently  jak  lines  mapk  mediates  mediating  mitogen  mm  myeloma  next  occur  oligonucleotide  proliferated  proliferative  ras  regardless  sense  shc  stat1  stat3  triggered 
Tagcloud (Difference) ?
a549  attenuation  carboxamide  competition  continuing  crosstalk  docking  efforts  emerging  emt  fak  focal  hinge  ky  methylbenzamido  motility  nck  orchestrated  paxillin  pharmacologic  phenylamino  smad  tgf  thiazole  traf2  transforming  triggers  validate  wnt 
accordingly  antisense  b9  cascade  cascades  distal  gp130  il  independently  jak  lines  mapk  mediates  mediating  mitogen  mm  myeloma  next  occur  oligonucleotide  proliferated  proliferative  ras  regardless  sense  shc  stat1  stat3  triggered 
Tagcloud (Intersection) ?