MAST1 and GCDH

Number of citations of the paper that reports this interaction (PMID 21163940)
13

Data Source:
BioGRID (two hybrid)

		MAST1	GCDH
Gene Name		microtubule associated serine/threonine kinase 1	glutaryl-CoA dehydrogenase
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Fatty-acyl-CoA Binding Glutaryl-CoA Dehydrogenase Activity Flavin Adenine Dinucleotide Binding
	Biological Process	Protein Phosphorylation Cytoskeleton Organization Intracellular Signal Transduction	Lysine Catabolic Process Tryptophan Metabolic Process Fatty Acid Oxidation Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process Fatty-acyl-CoA Biosynthetic Process
Pathways			Lysine catabolism Metabolism of amino acids and derivatives
Drugs			Flavin-Adenine Dinucleotide S-4-Nitrobutyryl-Coa
Diseases
GWAS			Mean corpuscular hemoglobin ( 19862010)
Protein-Protein Interactions		37 interactors: A2M AP1M2 APOE APP BLMH CDK5 CYP2C8 CYP2C9 DNAJB1 ECSIT EGFR ELAVL3 EXOC6 EXOSC1 FBXL12 FBXW4 GCDH IFIT3 IFIT5 LONP1 LOXL4 MGEA5 NOS3 PAXIP1 PRAM1 PRDX2 PSEN2 PTEN RAB3A RAB3D RAD23A RNF32 RNLS RPP30 SNTA1 SNTB2 STAMBPL1	10 interactors: A2M APOE CDC37 ECSIT EXOC6 MAST1 NOS3 PSEN1 PSEN2 RNF32
Entrez ID		22983	2639
HPRD ID		17469	01977
Ensembl ID		ENSG00000105613	ENSG00000105607
Uniprot IDs		Q9Y2H9	Q92947
PDB IDs		2M9X 3PS4	1SIQ 1SIR 2R0M 2R0N
Enriched GO Terms of Interacting Partners?		Catabolic Process Synapse Organization Negative Regulation Of Protein Metabolic Process Response To Stress Negative Regulation Of Cellular Protein Metabolic Process Response To Abiotic Stimulus Negative Regulation Of Presynaptic Membrane Organization Regulation Of Synaptic Plasticity Regulation Of Synaptic Transmission Regulation Of Oxidoreductase Activity Synapse Assembly Exocytosis Regulation Of Cellular Protein Metabolic Process Axon Development Response To Stimulus Regulation Of Presynaptic Membrane Organization Regulation Of Nitric-oxide Synthase Activity Regulation Of Protein Metabolic Process Negative Regulation Of Dendritic Spine Development Learning Or Memory Regulation Of Proteolysis Regulation Of Dendritic Spine Development Negative Regulation Of Cell Death Cognition Omega-hydroxylase P450 Pathway Synaptic Vesicle Exocytosis Anatomical Structure Morphogenesis Secretion By Cell Vesicle Docking Involved In Exocytosis Axonogenesis Positive Regulation Of Exocytosis Neuron Projection Development Vesicle-mediated Transport Glial Cell Differentiation Protein Metabolic Process Establishment Of Protein Localization Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cell Morphogenesis Involved In Neuron Differentiation Negative Regulation Of Neuron Differentiation Membrane Organization Oxidative Demethylation Protein Catabolic Process Establishment Of Vesicle Localization Oligodendrocyte Differentiation Positive Regulation Of Catalytic Activity Regulation Of ERBB Signaling Pathway Vesicle Docking Regulation Of Cellular Amino Acid Metabolic Process Endothelial Cell Migration Vesicle Localization	Regulation Of Oxidoreductase Activity Regulation Of Catalytic Activity Amyloid Precursor Protein Catabolic Process Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Beta-amyloid Metabolic Process Amyloid Precursor Protein Metabolic Process Intracellular Signal Transduction Nitric Oxide Mediated Signal Transduction Negative Regulation Of Platelet Activation Positive Regulation Of CGMP Biosynthetic Process Protein Localization Regulation Of Cellular Protein Metabolic Process Membrane Protein Ectodomain Proteolysis Notch Receptor Processing Positive Regulation Of CGMP Metabolic Process Establishment Of Localization In Cell Regulation Of Synaptic Plasticity Regulation Of CGMP Biosynthetic Process Regulation Of Epidermal Growth Factor-activated Receptor Activity Cell Differentiation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Protein Metabolic Process Endoplasmic Reticulum Calcium Ion Homeostasis Dorsal/ventral Neural Tube Patterning Regulation Of Platelet Activation Developmental Process Regulation Of CGMP Metabolic Process Cellular Localization Positive Regulation Of Coagulation Anatomical Structure Morphogenesis Protein Transport Membrane Protein Proteolysis Myeloid Cell Differentiation Brain Morphogenesis Negative Regulation Of Apoptotic Signaling Pathway Establishment Of Protein Localization Regulation Of Nitric-oxide Synthase Activity Regulation Of Phosphorus Metabolic Process Regulation Of Protein Kinase Activity Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Cellular Calcium Ion Homeostasis Regulation Of Signal Transduction Calcium Ion Homeostasis Regulation Of Synaptic Transmission Blood Circulation Thymus Development Negative Regulation Of Protein Phosphorylation
Tagcloud ?			1031c 1109t 148t 628a 700c 731g 963g aciduria acidurias athetosis checked cranial drowsiness dystonia fissure ganglia glutaric got infant intelligence leukoencephalopathy pediatrics peking psychomotor retardation sylvian vomiting w50r widening
Tagcloud (Difference) ?			1031c 1109t 148t 628a 700c 731g 963g aciduria acidurias athetosis checked cranial drowsiness dystonia fissure ganglia glutaric got infant intelligence leukoencephalopathy pediatrics peking psychomotor retardation sylvian vomiting w50r widening
Tagcloud (Intersection) ?