VASH1 and DHPS

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		VASH1	DHPS
Gene Name		vasohibin 1	deoxyhypusine synthase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm Endoplasmic Reticulum Apical Part Of Cell	Cytosol
	Molecular Function		Protein Binding Deoxyhypusine Synthase Activity
	Biological Process	Angiogenesis Negative Regulation Of Endothelial Cell Proliferation Cell Cycle Arrest Response To Wounding Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Lymphangiogenesis Regulation Of Cellular Senescence	Translation Positive Regulation Of Cell Proliferation Peptidyl-lysine Modification To Peptidyl-hypusine Positive Regulation Of T Cell Proliferation Glucose Homeostasis Post-translational Protein Modification Cellular Protein Metabolic Process Deoxyhypusine Biosynthetic Process From Spermidine Protein Homotetramerization
Pathways			Post-translational protein modification Hypusine synthesis from eIF5A-lysine Gamma carboxylation, hypusine formation and arylsulfatase activation
Drugs			Nicotinamide-Adenine-Dinucleotide 1-Guanidinium-7-Aminoheptane
Diseases
GWAS
Protein-Protein Interactions		1 interactors: DHPS	13 interactors: BRCA1 EIF5A EIF5A2 MAPK3 NIF3L1 NUDT18 PTPRH RAB27B REL RPL9 VASH1 WDYHV1 ZNF138
Entrez ID		22846	1725
HPRD ID		12353	02969
Ensembl ID		ENSG00000071246	ENSG00000095059
Uniprot IDs		Q7L8A9	P49366
PDB IDs			1DHS 1RLZ 1ROZ 1RQD
Enriched GO Terms of Interacting Partners?		Deoxyhypusine Biosynthetic Process From Spermidine Spermidine Catabolic Process Peptidyl-lysine Modification To Peptidyl-hypusine Polyamine Catabolic Process Polyamine Metabolic Process Protein Homotetramerization Positive Regulation Of T Cell Proliferation Protein Tetramerization Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Cellular Biogenic Amine Metabolic Process Amine Metabolic Process Regulation Of T Cell Proliferation Post-translational Protein Modification Glucose Homeostasis Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Peptidyl-lysine Modification Cellular Modified Amino Acid Metabolic Process Protein Homooligomerization Regulation Of T Cell Activation Positive Regulation Of Cell Activation Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Regulation Of Lymphocyte Activation Protein Oligomerization Regulation Of Cell Activation Regulation Of Cell Adhesion	Translational Frameshifting Positive Regulation Of Translational Termination Positive Regulation Of Translational Elongation Regulation Of Translational Termination Peptidyl-lysine Modification To Peptidyl-hypusine Positive Regulation Of Histone Acetylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Protein Complex Disassembly Translational Elongation Positive Regulation Of Cellular Biosynthetic Process Regulation Of Histone Acetylation Positive Regulation Of Protein Metabolic Process Negative Regulation Of Lymphangiogenesis Positive Regulation Of Histone H4-K20 Methylation DGDP Catabolic Process DADP Catabolic Process Positive Regulation Of Histone H4-K16 Acetylation Negative Regulation Of Apolipoprotein Binding Polyamine Homeostasis GDP Catabolic Process Positive Regulation Of Histone Modification Positive Regulation Of Translation Positive Regulation Of Histone H3-K9 Acetylation 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Cellular Macromolecule Biosynthetic Process Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Apoptotic Process Macromolecule Biosynthetic Process Dihydrobiopterin Metabolic Process Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Programmed Cell Death MRNA Transport Cell Death Regulation Of Protein Complex Disassembly Death Regulation Of Histone Modification Multivesicular Body Sorting Pathway Regulation Of Golgi Inheritance Positive Regulation Of Cellular Protein Metabolic Process Cellular Metabolic Process RNA Transport Caveolin-mediated Endocytosis Positive Regulation Of Histone Phosphorylation Cellular Response To Indole-3-methanol RNA Localization
Tagcloud ?			administrations antihypertensive blocker cas ceb curves diastolic dihydropyridine dihydropyridines dogs exerted felodipine hypertensive intravenous lasting lercanidipine nicardipine nitrendipine orally potency rec reference repeated shr spontaneously starting systolic tachyphylaxis
Tagcloud (Difference) ?			administrations antihypertensive blocker cas ceb curves diastolic dihydropyridine dihydropyridines dogs exerted felodipine hypertensive intravenous lasting lercanidipine nicardipine nitrendipine orally potency rec reference repeated shr spontaneously starting systolic tachyphylaxis
Tagcloud (Intersection) ?