ATF5 and CDC34

Number of citations of the paper that reports this interaction (PMID 10373550)
21

Data Source:
HPRD (two hybrid, in vivo)

		ATF5	CDC34
Gene Name		activating transcription factor 5	cell division cycle 34
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Transcription Factor Complex Cytoplasm	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Transcription Corepressor Activity Protein Binding Heat Shock Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity Ubiquitin Conjugating Enzyme Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Circadian Rhythm Post-embryonic Development Olfactory Bulb Interneuron Development Multicellular Organism Growth Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Astrocyte Differentiation Negative Regulation Of Nucleic Acid-templated Transcription	G1/S Transition Of Mitotic Cell Cycle Protein Polyubiquitination DNA Replication Initiation Cellular Protein Modification Process Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of CAMP-mediated Signaling Response To Growth Factor Protein K48-linked Ubiquitination Positive Regulation Of Inclusion Body Assembly
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: ATXN1 CCND3 CD34 CDC34 CEBPA CEBPE CEBPG DISC1 EP300 GABBR1 GABBR2 GIT2	45 interactors: ANAPC11 ATF5 BTRC CCNE1 CDK9 CDKN1B CREM CSNK2B CUL1 CUL2 CUL3 FBXL2 FBXL3 FBXO32 FBXO4 FBXO7 FBXW2 FBXW7 HIF1A ING4 ITCH MARCH1 MARCH2 MYBL2 MYOD1 NEDD4L NEDD8 NFKBIA PPARG RBX1 RELA RNF7 ROCK1 SDCBP SIAH1 SKP2 TBL1X TRIM21 TRIM28 UBA1 UBB VHL WWP2 ZFAND6 ZNRF1
Entrez ID		22809	997
HPRD ID		05906	00306
Ensembl ID		ENSG00000169136	ENSG00000099804
Uniprot IDs		Q9Y2D1	P49427
PDB IDs			2OB4 3RZ3
Enriched GO Terms of Interacting Partners?		Response To Stimulus Positive Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Macrophage Differentiation Positive Regulation Of Gene Expression Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Gamma-aminobutyric Acid Signaling Pathway Negative Regulation Of CAMP Biosynthetic Process Regulation Of Cellular Response To Heat Negative Regulation Of CAMP Metabolic Process Negative Regulation Of Nucleotide Metabolic Process Hemopoiesis Organ Development Myeloid Cell Differentiation Lung Development Respiratory Tube Development Negative Regulation Of Cellular Metabolic Process Regulation Of Cellular Process Positive Regulation Of Transcription, DNA-templated Immune System Development Immune System Process Respiratory System Development Regulation Of Adenylate Cyclase Activity Regulation Of Cyclase Activity Histone H2B Acetylation Positive Regulation Of Glial Cell Line-derived Neurotrophic Factor Secretion Negative Regulation Of Cellular Response To Heat Extracellular Vesicular Exosome Assembly Positive Regulation Of Macromolecule Biosynthetic Process Leukocyte Differentiation Positive Regulation Of Cytokine Production Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Cell-cell Signaling Regulation Of CAMP Biosynthetic Process Positive Regulation Of Macrophage Colony-stimulating Factor Production Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Cellular Response To Hypoxia Mesangial Cell-matrix Adhesion Positive Regulation Of Granulocyte Colony-stimulating Factor Production Regulation Of CAMP Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Macrophage Colony-stimulating Factor Production Vascular Wound Healing N-terminal Peptidyl-lysine Acetylation Myeloid Leukocyte Differentiation	Protein Modification By Small Protein Conjugation Protein Ubiquitination Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Protein Modification Process Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein Metabolic Process Cellular Macromolecule Catabolic Process Cellular Protein Metabolic Process Proteolysis Protein Polyubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Catabolic Process Cellular Metabolic Process Viral Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Positive Regulation Of Metabolic Process Protein Monoubiquitination Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Catabolic Process Mitotic Cell Cycle Phase Transition Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Gene Expression Cell Cycle Phase Transition Cellular Response To Oxygen Levels Cellular Response To Stimulus Regulation Of Protein Catabolic Process Response To Stimulus Cellular Response To Stress Regulation Of Protein Stability Notch Signaling Pathway Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Cell Cycle Negative Regulation Of RNA Biosynthetic Process Cell Cycle Regulation Of Transcription, DNA-templated Apoptotic Process Regulation Of Nucleic Acid-templated Transcription G1/S Transition Of Mitotic Cell Cycle Regulation Of RNA Biosynthetic Process Programmed Cell Death Regulation Of Protein Metabolic Process
Tagcloud ?		1beta activate cascades ccaat consistently cooperated ebp ebps effector elusive enhancer initiates interacted knockout luciferase mimicked nemo nlk opposite potentiated proinflammatory propagates proteasome screen stabilization stabilize tak1 though triggered	apparatus assemble associates box cdk cdk2 cerevisiae clock conjugating conjugation cul cullin dependency e3 facilitates governed imply ligase multiprotein p19 p45 periodic saccharomyces scf scfcdc4 skp1 skp2 tight ubiquitin
Tagcloud (Difference) ?		1beta activate cascades ccaat consistently cooperated ebp ebps effector elusive enhancer initiates interacted knockout luciferase mimicked nemo nlk opposite potentiated proinflammatory propagates proteasome screen stabilization stabilize tak1 though triggered	apparatus assemble associates box cdk cdk2 cerevisiae clock conjugating conjugation cul cullin dependency e3 facilitates governed imply ligase multiprotein p19 p45 periodic saccharomyces scf scfcdc4 skp1 skp2 tight ubiquitin
Tagcloud (Intersection) ?