XRN2 and ALDH1B1

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)

		XRN2	ALDH1B1
Gene Name		5-3 exoribonuclease 2	aldehyde dehydrogenase 1 family, member B1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Membrane Aggresome	Nucleoplasm Mitochondrion Mitochondrial Matrix Intracellular Membrane-bounded Organelle
	Molecular Function	Transcription Termination Site Sequence-specific DNA Binding Nuclease Activity 5'-3' Exoribonuclease Activity Zinc Ion Binding 5'-3' Exonuclease Activity Poly(A) RNA Binding	Aldehyde Dehydrogenase (NAD) Activity
	Biological Process	DNA Catabolic Process, Exonucleolytic DNA-templated Transcription, Termination Regulation Of Transcription, DNA-templated RNA Processing MRNA Processing RNA Catabolic Process Spermatogenesis Cell Growth RNA Metabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic	Carbohydrate Metabolic Process Ethanol Catabolic Process Oxidation-reduction Process
Pathways		Protein folding Chaperonin-mediated protein folding Association of TriC/CCT with target proteins during biosynthesis
Drugs			NADH
Diseases
GWAS
Protein-Protein Interactions		24 interactors: ALDH1B1 ATRN COMT CSNK2A1 CTSC DISC1 DXO EEF1A1 EIF3L EIF5A EIF6 ERG EXOSC10 EXOSC8 LSM3 MOCS3 MRPL4 MRPS10 PRAME PSMA3 TARDBP TIPARP TOLLIP UPF2	3 interactors: EXOSC10 FABP2 XRN2
Entrez ID		22803	219
HPRD ID		10309	00005
Ensembl ID		ENSG00000088930	ENSG00000137124
Uniprot IDs		Q9H0D6	P30837
PDB IDs
Enriched GO Terms of Interacting Partners?		Gene Expression Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Positive Regulation Of Protein Catabolic Process Aromatic Compound Catabolic Process MRNA Metabolic Process Nuclear MRNA Surveillance Translational Elongation RNA Surveillance Catabolic Process Regulation Of Protein Catabolic Process Translation Cellular Metabolic Process Translational Initiation RNA Metabolic Process Positive Regulation Of Protein Metabolic Process Cellular Macromolecule Catabolic Process Nitrogen Compound Metabolic Process Biosynthetic Process Nuclear Export Ribonucleoprotein Complex Biogenesis Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Cellular Macromolecule Biosynthetic Process Metabolic Process Estrogen Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Macromolecule Biosynthetic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process RNA Localization Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Wnt Signaling Pathway Ribosome Biogenesis Regulation Of Protein Metabolic Process Cellular Aromatic Compound Metabolic Process Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Homocysteine Metabolic Process TRNA Wobble Position Uridine Thiolation Enzyme Active Site Formation Via L-cysteine Persulfide Cellular Response To Phosphate Starvation Negative Regulation Of Potassium Ion Export Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of RNA Stability Cellular Protein Metabolic Process Regulation Of Homocysteine Metabolic Process Protein Adenylylation Regulation Of Heart Rate By Hormone	RNA Phosphodiester Bond Hydrolysis, Exonucleolytic RNA Phosphodiester Bond Hydrolysis Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription RNA Catabolic Process Nuclear Polyadenylation-dependent RRNA Catabolic Process CUT Catabolic Process Nucleic Acid Phosphodiester Bond Hydrolysis Nuclear MRNA Surveillance RNA Surveillance Aromatic Compound Catabolic Process Histone MRNA Catabolic Process Dosage Compensation By Inactivation Of X Chromosome Intracellular MRNA Localization RRNA Catabolic Process Dosage Compensation MRNA Metabolic Process RNA Processing Maturation Of 5.8S RRNA Histone MRNA Metabolic Process Cellular Macromolecule Catabolic Process DNA Catabolic Process, Exonucleolytic DNA-templated Transcription, Termination Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Digestion RRNA Processing Catabolic Process RRNA Metabolic Process DNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process Cell Growth RNA Localization MRNA Catabolic Process
Tagcloud ?		8s arabidopsis at1g52930 at3g15460 atbrx1 biogenesis brx1 bypassed ets eukaryotes export implying intermediates its1 leaves nucleolus orthologs plant pointed processing rbfs ribosomal ribosome rrna spacer steps thaliana transcribed ubiquitously
Tagcloud (Difference) ?		8s arabidopsis at1g52930 at3g15460 atbrx1 biogenesis brx1 bypassed ets eukaryotes export implying intermediates its1 leaves nucleolus orthologs plant pointed processing rbfs ribosomal ribosome rrna spacer steps thaliana transcribed ubiquitously
Tagcloud (Intersection) ?