FHL3 and AMBP

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FHL3	AMBP
Gene Name		four and a half LIM domains 3	alpha-1-microglobulin/bikunin precursor
Image
Gene Ontology Annotations	Cellular Component	Stress Fiber Nucleus Focal Adhesion Z Disc	Extracellular Region Extracellular Space Plasma Membrane Cell Surface Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Actin Binding Zinc Ion Binding	Serine-type Endopeptidase Inhibitor Activity Protein Binding Calcium Channel Inhibitor Activity IgA Binding Heme Binding Small Molecule Binding Protein Homodimerization Activity Calcium Oxalate Binding
	Biological Process	Muscle Organ Development Actin Cytoskeleton Organization	Receptor-mediated Endocytosis Cell Adhesion Female Pregnancy Negative Regulation Of Endopeptidase Activity Viral Process Protein-chromophore Linkage Protein Catabolic Process Heme Catabolic Process Negative Regulation Of JNK Cascade Negative Regulation Of Immune Response
Pathways			Scavenging of heme from plasma
Drugs			Human Serum Albumin Serum albumin iodonated
Diseases
GWAS
Protein-Protein Interactions		88 interactors: A1CF ACTB ADAM15 ADAMTSL4 AIMP2 AMBP C14orf105 C9orf116 CDC25B CDC42EP1 CNNM3 CORO1A CSF1 CTBP2 DCDC2B E2F8 EFCAB12 EPHA10 EPM2AIP1 FAM154A FAM71C FAM90A1 FBXL18 FHL2 FHL5 FOSL2 GATA2 GCM2 HIPK1 HYAL2 ITGA7 KIRREL2 KLF3 KLF8 KRTAP12-1 KRTAP12-2 KTI12 LASP1 LMO2 LNX1 MAPK1 MED15 MPZL1 MRPL27 MYBPC1 MYBPHL MZF1 NPRL3 P4HA2 PAK7 PATL1 PHC2 PHF21A PLEKHF2 PPIG PTPN6 QRICH1 RAD21 RBM42 RFX3 RFX6 RHEBL1 RNMTL1 SAP30BP SLAIN1 SLC25A46 SLC44A3 SMAD2 SMAD3 SMAD4 SNRPG SREBF2 SRF TMX3 TRAF3IP2 TRIM27 TRIP6 TRO TTLL10 TYK2 TYMSOS UBE2I UBE2Q1 WNK1 YPEL3 ZNF417 ZNF512B ZNRD1	12 interactors: A2M ALB COX8A DAAM1 ENO1 F2 FHL3 FN1 GRB2 PIK3CA PIK3R3 STAT3
Entrez ID		2275	259
HPRD ID		09101	01467
Ensembl ID		ENSG00000183386	ENSG00000106927
Uniprot IDs		Q13643 Q96C98	P02760
PDB IDs		1WYH 2CUQ 2EHE	1BIK 3QKG 4ES7
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Transcription, DNA-templated Gene Expression RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process SMAD Protein Complex Assembly Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Cellular Process Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Cell Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Cell Proliferation Negative Regulation Of RNA Biosynthetic Process Tissue Development Positive Regulation Of Cellular Metabolic Process Cell Death Death Multicellular Organismal Homeostasis Positive Regulation Of Epithelial To Mesenchymal Transition Endoderm Development Negative Regulation Of Cell Growth Embryonic Organ Development Positive Regulation Of Metabolic Process Primary MiRNA Processing Organ Development Apoptotic Process	Platelet Activation Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Cell Activation Response To Wounding Acute-phase Response Leukocyte Migration Platelet Degranulation Acute Inflammatory Response Regulation Of Growth Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Blood Coagulation, Intrinsic Pathway Phosphatidylinositol-3-phosphate Biosynthetic Process Insulin Receptor Signaling Pathway Response To Peptide Hormone Cellular Response To Organonitrogen Compound Response To Peptide Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Cellular Response To Hormone Stimulus Neurotrophin Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Defense Response Regulation Of Developmental Growth Response To Insulin Vesicle-mediated Transport Movement Of Cell Or Subcellular Component Response To Stress Positive Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Response To Organonitrogen Compound Exocytosis Cell Migration Regulation Of Cell Growth T Cell Costimulation Enzyme Linked Receptor Protein Signaling Pathway Cell Motility Phosphatidylinositol Phosphorylation Positive Regulation Of Reactive Oxygen Species Metabolic Process Lipid Phosphorylation Response To Hormone Extracellular Matrix Disassembly Hypomethylation Of CpG Island Maintenance Of Mitochondrion Location Negative Regulation Of Complement Activation, Lectin Pathway Regulation Of Multicellular Organism Growth Inflammatory Response Anatomical Structure Formation Involved In Morphogenesis
Tagcloud ?		accompanied adhesion anchorage antiproliferative arrest b1 cip1 downregulated g1 g2 half implicated interfering knockdown lim marked marker member mobility p21 progression regulator sirna suppressed thereby transduction unclear waf1	2nh2 2oh amide aminomethylenebisphosphonate atom azido bisphosphonate bisphosphonates ch2 competitively constructing differing hydrolytic hydrophilic inorganic labelling nc nh2 photoactivatable photoaffinity po3 pocket ppase ppases ppi proton pumping pyrophosphatases vacuoles
Tagcloud (Difference) ?		accompanied adhesion anchorage antiproliferative arrest b1 cip1 downregulated g1 g2 half implicated interfering knockdown lim marked marker member mobility p21 progression regulator sirna suppressed thereby transduction unclear waf1	2nh2 2oh amide aminomethylenebisphosphonate atom azido bisphosphonate bisphosphonates ch2 competitively constructing differing hydrolytic hydrophilic inorganic labelling nc nh2 photoactivatable photoaffinity po3 pocket ppase ppases ppi proton pumping pyrophosphatases vacuoles
Tagcloud (Intersection) ?