FGF12 and MAPK8IP2

Number of citations of the paper that reports this interaction (PMID 11378392)
22

Data Source:
HPRD (in vivo, two hybrid)

		FGF12	MAPK8IP2
Gene Name		fibroblast growth factor 12	mitogen-activated protein kinase 8 interacting protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus	Cytoplasm Neuronal Cell Body Protein Complex Neuronal Postsynaptic Density
	Molecular Function	Fibroblast Growth Factor Receptor Binding Growth Factor Activity Heparin Binding Sodium Channel Regulator Activity Ion Channel Binding	Beta-amyloid Binding MAP-kinase Scaffold Activity Structural Molecule Activity Protein Binding Kinesin Binding Protein Kinase Binding Protein Kinase Activator Activity Protein Complex Binding
	Biological Process	Regulation Of Membrane Depolarization Signal Transduction JNK Cascade Cell-cell Signaling Synaptic Transmission Nervous System Development Heart Development Adult Locomotory Behavior Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Sodium Ion Transport Neuromuscular Process Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Sodium Ion Transmembrane Transport Regulation Of Sodium Ion Transmembrane Transporter Activity Negative Regulation Of Cation Channel Activity	MAPK Cascade Behavioral Fear Response Signal Complex Assembly JNK Cascade Mating Behavior Regulation Of Receptor Activity Positive Regulation Of Stress-activated MAPK Cascade Social Behavior Positive Regulation Of Protein Kinase Activity Regulation Of JNK Cascade Nonassociative Learning Dendrite Morphogenesis Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity
Pathways
Drugs
Diseases
GWAS		Ileal carcinoids ( 21139019) Major depressive disorder ( 23377640) Metabolite levels ( 19043545) Sleep quality ( 23728906)
Protein-Protein Interactions		13 interactors: APP COIL DACH1 DCTD IKZF1 LZTS2 MAPK13 MAPK8IP2 NEDD4 NEDD4L SRPK1 SRPK2 ZNF460	52 interactors: ADRB2 AFG3L2 APP ASRGL1 BBS10 C14orf1 CFL1 CHN1 CRMP1 DUSP16 EGFR ERBB2 EZH2 FGF12 FSCN1 GBP2 ITSN1 KIFC2 KLC1 LRP1 LRP2 LRP8 MAGED4B MAP2K3 MAP2K7 MAP3K10 MAP3K11 MAP3K12 MAPK10 MAPK8 MAPK8IP1 MAPK8IP3 MAPK9 MASP1 NDUFS6 PLXNA3 PRSS23 RAI1 RBX1 RPS6KB2 SMARCB1 SMS SYNE2 TIAM1 TP53BP2 UNC119 VCP VPS33B VRK2 YY1AP1 ZNF593 ZNF784
Entrez ID		2257	23542
HPRD ID		03303	09674
Ensembl ID		ENSG00000114279	ENSG00000008735
Uniprot IDs		P61328	Q13387
PDB IDs		1Q1U
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Sodium Ion Transport RNA Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Ion Transmembrane Transporter Activity Nucleobase-containing Compound Metabolic Process Regulation Of Transmembrane Transporter Activity Positive Regulation Of Viral Genome Replication Gene Expression Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Suckling Behavior Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Mating Behavior Regulation Of Potassium Ion Transmembrane Transport Protein Monoubiquitination Cellular Macromolecular Complex Assembly Nitrogen Compound Metabolic Process Negative Regulation Of Viral Genome Replication Regulation Of Membrane Potential Regulation Of Metabolic Process Mating Neuromuscular Junction Development Regulation Of Potassium Ion Transport Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Sodium Ion Transport Regulation Of MRNA Splicing, Via Spliceosome Response To Stress Positive Regulation Of Neutrophil Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Nuclear Speck Organization Transmission Of Virus Development Involved In Symbiotic Interaction Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Cellular Metabolic Process Negative Regulation Of Viral Process Response To Osmotic Stress Regulation Of MRNA Processing Regulation Of Synapse Structure Or Activity Synaptic Growth At Neuromuscular Junction Positive Regulation Of Caveolin-mediated Endocytosis Negative Regulation Of Ion Transport Regulation Of Ion Transmembrane Transport MRNA Processing Feeding Behavior	Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade JNK Cascade Signal Transduction By Phosphorylation MAPK Cascade Regulation Of Protein Kinase Activity Regulation Of MAPK Cascade Regulation Of Kinase Activity Regulation Of Phosphorylation Positive Regulation Of Protein Kinase Activity Positive Regulation Of Catalytic Activity Positive Regulation Of Kinase Activity JUN Phosphorylation Regulation Of MAP Kinase Activity Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Transferase Activity Positive Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Signal Transduction Positive Regulation Of MAP Kinase Activity Response To Stress Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of MAPK Cascade Regulation Of Signal Transduction Response To Light Stimulus Response To External Stimulus Response To Radiation Regulation Of Signaling Intracellular Signal Transduction Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Axon Guidance Regulation Of Intracellular Signal Transduction Signal Transduction Axonogenesis Phosphorylation Cell Part Morphogenesis Axon Development Response To Stimulus Cell Morphogenesis Involved In Neuron Differentiation Response To Abiotic Stimulus Protein Phosphorylation Cellular Response To Stress Signaling
Tagcloud ?		bisulfite breed broilers cgis chicken chickens contrasts cr1 differentially exons fgf14 fgf18 fgfr2 fgfr3 intergenic introns medip methylated poultry prominently recessive rock seq tails utrs validate wrr xh xinhua
Tagcloud (Difference) ?		bisulfite breed broilers cgis chicken chickens contrasts cr1 differentially exons fgf14 fgf18 fgfr2 fgfr3 intergenic introns medip methylated poultry prominently recessive rock seq tails utrs validate wrr xh xinhua
Tagcloud (Intersection) ?