ABCD2 and PEX19

Number of citations of the paper that reports this interaction (PMID 10704444)
47

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid, in vitro, in vivo)

		ABCD2	PEX19
Gene Name		ATP-binding cassette, sub-family D (ALD), member 2	peroxisomal biogenesis factor 19
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Peroxisome Peroxisomal Membrane Cytosol Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Cytoplasm Peroxisome Peroxisomal Membrane Cytosol Integral Component Of Membrane Brush Border Membrane Intracellular Membrane-bounded Organelle Protein Complex
	Molecular Function	Protein Binding ATP Binding ATPase Activity, Coupled To Transmembrane Movement Of Substances Protein Homodimerization Activity	Protein Binding Peroxisome Membrane Class-1 Targeting Sequence Binding Protein N-terminus Binding ATPase Binding
	Biological Process	Very Long-chain Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Positive Regulation Of Fatty Acid Beta-oxidation Very Long-chain Fatty Acid Catabolic Process Transmembrane Transport	Protein Targeting To Peroxisome Peroxisome Organization Peroxisome Membrane Biogenesis Peroxisome Fission Protein Import Into Peroxisome Membrane Protein Stabilization Transmembrane Transport Chaperone-mediated Protein Folding Chaperone-mediated Protein Transport Establishment Of Protein Localization To Peroxisome Negative Regulation Of Lipid Binding
Pathways		ABC-family proteins mediated transport ABCA transporters in lipid homeostasis	ABC-family proteins mediated transport ABCA transporters in lipid homeostasis
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: ABCD1 ABCD3 PEX19	32 interactors: ABCD1 ABCD2 ABCD3 CDC25A CDKN2A EIF1B F11R FKBP7 GSKIP IL23A IRF3 KIFAP3 MFSD5 OIP5 PEX10 PEX11A PEX11B PEX12 PEX13 PEX14 PEX16 PEX26 PEX3 PMP22 PPIB PXMP4 SLC25A17 SLC34A1 SMAD2 SRPK1 STK3 TMEM54
Entrez ID		225	5824
HPRD ID		03051	02610
Ensembl ID			ENSG00000162735
Uniprot IDs		Q9UBJ2	P40855
PDB IDs			2W85 2WL8 3AJB 3MK4
Enriched GO Terms of Interacting Partners?		Peroxisome Organization Very Long-chain Fatty Acid Catabolic Process Peroxisomal Membrane Transport Very Long-chain Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Cellular Lipid Catabolic Process Negative Regulation Of Lipid Binding Peroxisomal Long-chain Fatty Acid Import Lipid Modification Carboxylic Acid Catabolic Process Lipid Catabolic Process Transmembrane Transport Peroxisome Membrane Biogenesis Fatty Acid Metabolic Process Chaperone-mediated Protein Transport Protein Import Into Peroxisome Membrane Long-chain Fatty Acid Catabolic Process Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Alpha-linolenic Acid Metabolic Process Linoleic Acid Metabolic Process Peroxisome Fission Monocarboxylic Acid Metabolic Process Organelle Organization Establishment Of Protein Localization To Peroxisome Protein Targeting To Peroxisome Membrane Biogenesis Cellular Lipid Metabolic Process Long-chain Fatty Acid Transport Carboxylic Acid Metabolic Process Intracellular Protein Transmembrane Transport Organic Acid Metabolic Process Protein Transmembrane Transport Fatty Acid Transport Chaperone-mediated Protein Folding Lipid Metabolic Process Transport Protein Stabilization Oxidation-reduction Process Intracellular Transport Negative Regulation Of Binding Unsaturated Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Catabolic Process Monocarboxylic Acid Transport Regulation Of Protein Stability Protein Import Establishment Of Localization In Cell	Peroxisome Organization Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Protein Import Into Peroxisome Matrix Intracellular Protein Transmembrane Transport Protein Transmembrane Transport Peroxisomal Membrane Transport Protein Import Peroxisome Membrane Biogenesis Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Very Long-chain Fatty Acid Catabolic Process Protein Import Into Peroxisome Membrane Organelle Organization Protein To Membrane Docking Transmembrane Transport Establishment Of Protein Localization To Organelle Fatty Acid Beta-oxidation Protein Targeting Cellular Lipid Catabolic Process Protein Localization To Organelle Regulation Of Peroxisome Size Lipid Modification Membrane Biogenesis Carboxylic Acid Catabolic Process Protein Import Into Peroxisome Matrix, Docking Very Long-chain Fatty Acid Metabolic Process Lipid Catabolic Process Cytoplasmic Transport Fatty Acid Alpha-oxidation Fatty Acid Metabolic Process Establishment Of Protein Localization Peroxisome Fission Intracellular Transport Protein Localization Cellular Localization Intracellular Protein Transport Transport Establishment Of Localization In Cell Establishment Of Protein Localization To Membrane Cellular Protein Localization Protein Stabilization Membrane Docking Posttranscriptional Regulation Of Gene Expression Protein Transport Positive Regulation Of Viral Genome Replication Cellular Component Assembly Regulation Of Defense Response To Virus By Host Monocarboxylic Acid Metabolic Process
Tagcloud ?		abcd1 accessibility acne adrenoleukodystrophy ald allogeneic allowing cald cis compensate curative demyelination devastating eighteen fivefold fourfold halt hsct hypothesize immediately manifest metabolically monocytes nevertheless peroxisomal retinoids thp urgently virtually	amphipathic anchored biogenesis chaperone concerted delivers docking engagement hydrophobic hydrophobicity inserted insertion intercalation moieties peroxisome pex3 promotes prompt reconstitute segment segments sequential steps ta tail tmd translationally uncharacterized unconventional
Tagcloud (Difference) ?		abcd1 accessibility acne adrenoleukodystrophy ald allogeneic allowing cald cis compensate curative demyelination devastating eighteen fivefold fourfold halt hsct hypothesize immediately manifest metabolically monocytes nevertheless peroxisomal retinoids thp urgently virtually	amphipathic anchored biogenesis chaperone concerted delivers docking engagement hydrophobic hydrophobicity inserted insertion intercalation moieties peroxisome pex3 promotes prompt reconstitute segment segments sequential steps ta tail tmd translationally uncharacterized unconventional
Tagcloud (Intersection) ?