FGF3 and EBNA1BP2

Number of citations of the paper that reports this interaction (PMID 11438656)
9

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		FGF3	EBNA1BP2
Gene Name		fibroblast growth factor 3	EBNA1 binding protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Golgi Apparatus	Nucleus Nucleolus Membrane
	Molecular Function	Fibroblast Growth Factor Receptor Binding Protein Binding Growth Factor Activity	Poly(A) RNA Binding
	Biological Process	Organ Induction Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Cell-cell Signaling Positive Regulation Of Cell Proliferation Insulin Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Anatomical Structure Morphogenesis Otic Vesicle Formation Post-anal Tail Morphogenesis Fc-epsilon Receptor Signaling Pathway Innate Immune Response Neurotrophin TRK Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling Thymus Development Semicircular Canal Morphogenesis Positive Regulation Of Cell Division Negative Regulation Of Cardiac Muscle Tissue Development	Ribosome Biogenesis
Pathways		Signaling by the B Cell Receptor (BCR) Signaling by FGFR in disease Phospholipase C-mediated cascade SHC-mediated cascade Signaling by EGFRvIII in Cancer Signaling by SCF-KIT Signaling by FGFR2 mutants DAP12 signaling Downstream signaling events of B Cell Receptor (BCR) PI3K/AKT activation PI-3K cascade PI3K Cascade Negative regulation of FGFR signaling Signaling by PDGF DAP12 interactions GAB1 signalosome Signaling by ERBB4 Role of LAT2/NTAL/LAB on calcium mobilization Constitutive PI3K/AKT Signaling in Cancer Activated point mutants of FGFR2 PI3K events in ERBB4 signaling Signaling by ERBB2 Signaling by EGFR Downstream signal transduction Fc epsilon receptor (FCERI) signaling Signaling by FGFR mutants Signaling by EGFR in Cancer PI3K/AKT Signaling in Cancer Adaptive Immune System IRS-mediated signalling PIP3 activates AKT signaling IGF1R signaling cascade IRS-related events triggered by IGF1R PI3K events in ERBB2 signaling Downstream signaling of activated FGFR FGFR1b ligand binding and activation FGFR ligand binding and activation FGFR2b ligand binding and activation Signaling by Insulin receptor Innate Immune System Signalling by NGF Insulin receptor signalling cascade IRS-related events Signaling by Ligand-Responsive EGFR Variants in Cancer NGF signalling via TRKA from the plasma membrane Signaling by Overexpressed Wild-Type EGFR in Cancer Signaling by FGFR IRS-mediated signalling FGFR2 ligand binding and activation FRS2-mediated cascade FGFR1 ligand binding and activation Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) PI3K Cascade
Drugs
Diseases
GWAS		Breast cancer ( 20453838) Protein quantitative trait loci ( 18464913)
Protein-Protein Interactions		6 interactors: EBNA1BP2 FGFR1 FGFR2 FGFR3 FGFR4 RPS2	4 interactors: FAM9B FBXW7 FGF3 GSK3A
Entrez ID		2248	10969
HPRD ID		01289	16849
Ensembl ID			ENSG00000117395
Uniprot IDs		P11487	H7C2Q8 Q6IB29 Q99848
PDB IDs
Enriched GO Terms of Interacting Partners?		Phosphatidylinositol-mediated Signaling Insulin Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Alveolar Secondary Septum Development Fibroblast Growth Factor Receptor Signaling Pathway Involved In Orbitofrontal Cortex Development Protein Autophosphorylation Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Ventricular Zone Neuroblast Division Lung Development Lung Alveolus Development Respiratory Tube Development Peptidyl-tyrosine Phosphorylation Fc Receptor Signaling Pathway Orbitofrontal Cortex Development Respiratory System Development Cell Fate Commitment Response To Insulin Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Positive Regulation Of Phospholipase Activity Forebrain Ventricular Zone Progenitor Cell Division Positive Regulation Of MAPKKK Cascade By Fibroblast Growth Factor Receptor Signaling Pathway Midbrain Development Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Positive Regulation Of MAPK Cascade Response To Peptide Hormone Immune Response-regulating Signaling Pathway Cellular Response To Organonitrogen Compound Response To Peptide Positive Regulation Of ERK1 And ERK2 Cascade Lung Saccule Development Cellular Response To Growth Factor Stimulus Forebrain Neuroblast Division Cellular Response To Hormone Stimulus Response To Growth Factor Lung-associated Mesenchyme Development Regulation Of MAPK Cascade Positive Regulation Of Catalytic Activity Regulation Of Organ Morphogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Lens Fiber Cell Development	Negative Regulation Of Cardiac Muscle Tissue Development Negative Regulation Of Striated Muscle Tissue Development Negative Regulation Of Muscle Organ Development Regulation Of Cardiac Muscle Tissue Development Regulation Of Striated Muscle Tissue Development Phosphatidylinositol-mediated Signaling Insulin Receptor Signaling Pathway Negative Regulation Of UDP-glucose Catabolic Process Negative Regulation Of SREBP Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Organ Morphogenesis Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Triglyceride Biosynthetic Process Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Positive Regulation Of Protein Catabolic Process Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Adrenergic Receptor Signaling Pathway Proteasomal Protein Catabolic Process Fc Receptor Signaling Pathway Response To Insulin Hypermethylation Of CpG Island Negative Regulation Of Hepatocyte Proliferation Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Negative Regulation Of DNA Endoreduplication Cellular Response To Interleukin-3 Positive Regulation Of Glycogen (starch) Synthase Activity Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Adrenergic Receptor Signaling Pathway Negative Regulation Of Cardiac Muscle Cell Differentiation Immune Response-regulating Cell Surface Receptor Signaling Pathway Negative Regulation Of Glycogen (starch) Synthase Activity Regulation Of Protein Catabolic Process Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Oxidative Stress-induced Cell Death Response To Peptide Hormone Anatomical Structure Morphogenesis Immune Response-regulating Signaling Pathway Positive Regulation Of Protein Kinase Activity
Tagcloud ?		11q13 4nqo 7f4 amplicon amplification amplified cavity ccnd1 chr distal example fgf4 heterozygosity hras1 inbred inconsistently involving loh murine neck nitroquinoline portion predispose scc strikingly syntenic telomeric thirds twofold
Tagcloud (Difference) ?		11q13 4nqo 7f4 amplicon amplification amplified cavity ccnd1 chr distal example fgf4 heterozygosity hras1 inbred inconsistently involving loh murine neck nitroquinoline portion predispose scc strikingly syntenic telomeric thirds twofold
Tagcloud (Intersection) ?