ENSA and ABCC8

Number of citations of the paper that reports this interaction (PMID 9653196)
8

Data Source:
HPRD (in vivo)

		ENSA	ABCC8
Gene Name		endosulfine alpha	ATP-binding cassette, sub-family C (CFTR/MRP), member 8
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Plasma Membrane Voltage-gated Potassium Channel Complex
	Molecular Function	Protein Phosphatase Inhibitor Activity Receptor Binding Ion Channel Inhibitor Activity Protein Phosphatase Type 2A Regulator Activity Phosphatase Inhibitor Activity Potassium Channel Inhibitor Activity Protein Phosphatase 2A Binding	ATP Binding Sulfonylurea Receptor Activity Potassium Ion Transmembrane Transporter Activity ATPase Activity, Coupled To Transmembrane Movement Of Substances Ion Channel Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Transport Mitotic Nuclear Division Response To Nutrient Response To Glucose Negative Regulation Of Catalytic Activity Regulation Of Catalytic Activity Regulation Of Insulin Secretion Cell Division	Carbohydrate Metabolic Process Energy Reserve Metabolic Process Potassium Ion Transport Signal Transduction Synaptic Transmission Small Molecule Metabolic Process Regulation Of Insulin Secretion Transmembrane Transport Potassium Ion Transmembrane Transport
Pathways		MASTL Facilitates Mitotic Progression Mitotic Prophase Cell Cycle, Mitotic M Phase	Inwardly rectifying K+ channels ABC-family proteins mediated transport Integration of energy metabolism ATP sensitive Potassium channels Regulation of insulin secretion Potassium Channels
Drugs			Adenosine triphosphate Glimepiride Chlorpropamide Nateglinide Repaglinide Glyburide Glipizide Gliclazide Tolbutamide Gliquidone Mitiglinide Glycodiazine
Diseases
GWAS		Rhegmatogenous retinal detachment ( 23585552)
Protein-Protein Interactions		9 interactors: ABCC8 ACD ARIH2 ENO2 KCTD15 POT1 PSEN1 RAP2A SNCA	4 interactors: CRYBB1 ENSA KCNJ11 KCNJ8
Entrez ID		2029	6833
HPRD ID		11927	02741
Ensembl ID		ENSG00000143420	ENSG00000006071
Uniprot IDs		A6NMQ3 O43768	Q09428
PDB IDs
Enriched GO Terms of Interacting Partners?		Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Capping Positive Regulation Of Telomerase Activity Negative Regulation Of Chromosome Organization Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Receptor Recycling Regulation Of Telomerase Activity Regulation Of Telomere Maintenance Positive Regulation Of DNA Biosynthetic Process Positive Regulation Of Transferase Activity Regulation Of Receptor Recycling Regulation Of Chromosome Organization Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Positive Regulation Of DNA Replication Telomere Maintenance Ammonium Transport Cellular Component Assembly Regulation Of Cellular Component Organization Negative Regulation Of Thrombin Receptor Signaling Pathway Cajal-Retzius Cell Differentiation Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Beta-amyloid Formation Generation Of Precursor Metabolites And Energy Negative Regulation Of DNA Metabolic Process Synaptic Vesicle Transport Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Segmentation Negative Regulation Of Biosynthetic Process Regulation Of DNA Replication Negative Regulation Of Dopamine Metabolic Process Telomere Formation Via Telomerase Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Serotonin Uptake Negative Regulation Of Cellular Respiration Synaptic Transmission Regulation Of Neurotransmitter Levels Positive Regulation Of Cellular Metabolic Process Positive Regulation Of DNA Metabolic Process Negative Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of Oxidative Phosphorylation Synaptic Vesicle Targeting	Potassium Ion Import Response To Glucose Potassium Ion Transmembrane Transport Response To Carbohydrate Regulation Of Insulin Secretion Potassium Ion Transport Regulation Of Peptide Hormone Secretion Regulation Of Hormone Secretion Cellular Response To Nicotine Regulation Of Protein Secretion Regulation Of Ion Transmembrane Transport Synaptic Transmission Regulation Of Ion Transport Regulation Of Protein Transport Regulation Of Secretion Response To ATP Response To Organic Substance Monovalent Inorganic Cation Transport Regulation Of Establishment Of Protein Localization Positive Regulation Of Cation Channel Activity Vasodilation Response To Ischemia Response To PH Response To Testosterone Regulation Of Protein Localization Response To Nicotine Cellular Response To Alkaloid Negative Regulation Of Insulin Secretion Metal Ion Transport Response To Lipid Negative Regulation Of Peptide Secretion Response To Organic Cyclic Compound Response To Exogenous DsRNA Cell-cell Signaling Positive Regulation Of Ion Transmembrane Transporter Activity Cation Transmembrane Transport Positive Regulation Of Transporter Activity Cellular Response To Glucose Stimulus Regulation Of Cellular Localization Negative Regulation Of Hormone Secretion Response To DsRNA Regulation Of Blood Vessel Size Regulation Of Tube Size Cellular Glucose Homeostasis Positive Regulation Of Ion Transmembrane Transport Regulation Of Cation Channel Activity Cellular Response To Carbohydrate Stimulus Neurological System Process Cation Transport Negative Regulation Of Protein Secretion
Tagcloud ?			2kd antigenic antigens atp2a2 autoantibodies candidates cd8 copyright destruction encoded glucagon goal infiltrating islet islets min6 nod pancreatic pathogenesis pcsk2 peg3 producing proglucagon protected recognize reserved rights scg2 specificities
Tagcloud (Difference) ?			2kd antigenic antigens atp2a2 autoantibodies candidates cd8 copyright destruction encoded glucagon goal infiltrating islet islets min6 nod pancreatic pathogenesis pcsk2 peg3 producing proglucagon protected recognize reserved rights scg2 specificities
Tagcloud (Intersection) ?