DTX3 and UBE2DNL

Number of citations of the paper that reports this interaction (PMID 19549727)
40

Data Source:
BioGRID (two hybrid)

		DTX3	UBE2DNL
Gene Name		deltex 3, E3 ubiquitin ligase	ubiquitin-conjugating enzyme E2D N-terminal like (pseudogene)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm
	Molecular Function	Zinc Ion Binding Ligase Activity
	Biological Process	Notch Signaling Pathway Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		25 interactors: DTX1 DTX2 RNF141 RNF38 TRAF4 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2DNL UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2L3 UBE2L6 UBE2V1 UBE2W UEVLD USP1 USP2 USP21 XIAP ZDHHC17	3 interactors: APP DTX3 RNF114
Entrez ID		196403	100131816
HPRD ID		16842
Ensembl ID		ENSG00000178498	ENSG00000229547
Uniprot IDs		Q8N9I9
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Protein Modification Process Protein K48-linked Ubiquitination Protein Polyubiquitination Cellular Protein Metabolic Process Protein K11-linked Ubiquitination Protein Metabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Metabolic Process Proteolysis ISG15-protein Conjugation Protein K63-linked Ubiquitination Regulation Of Proteasomal Protein Catabolic Process Catabolic Process Toll-like Receptor 4 Signaling Pathway Regulation Of Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Metabolic Process Regulation Of Proteolysis Regulation Of Innate Immune Response Toll-like Receptor Signaling Pathway Cellular Response To Stress Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Protein Ubiquitination Protein Monoubiquitination Activation Of Innate Immune Response Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Innate Immune Response TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Protein Ubiquitination Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Regulation Of Cellular Protein Metabolic Process Cellular Response To Stimulus Regulation Of Ubiquitin-protein Transferase Activity Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To DNA Damage Stimulus	Notch Signaling Pathway Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Copper Ion Homeostasis Cellular Protein Modification Process Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Sexual Reproduction Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Reproduction Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Cellular Protein Metabolic Process Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death
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