S1PR1 and CMSS1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		S1PR1	CMSS1
Gene Name		sphingosine-1-phosphate receptor 1	cms1 ribosomal small subunit homolog (yeast)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Endosome Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Intrinsic Component Of Plasma Membrane Membrane Raft
	Molecular Function	G-protein Coupled Receptor Binding G-protein Coupled Receptor Activity Sphingosine-1-phosphate Receptor Activity Sphingolipid Binding	Poly(A) RNA Binding
	Biological Process	Angiogenesis Blood Vessel Maturation Cardiac Muscle Tissue Growth Involved In Heart Morphogenesis Sphingosine-1-phosphate Signaling Pathway Chemotaxis Cell Adhesion G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Brain Development Cell Migration Transmission Of Nerve Impulse Lamellipodium Assembly Regulation Of Cell Adhesion Neuron Differentiation Positive Regulation Of Cell Migration Regulation Of Bone Mineralization Actin Cytoskeleton Reorganization Positive Regulation Of Ras GTPase Activity Regulation Of Bone Resorption Endothelial Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Positive Chemotaxis Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G-protein Coupled Signaling Pathway Negative Regulation Of Stress Fiber Assembly Heart Trabecula Morphogenesis T Cell Migration
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding Lysosphingolipid and LPA receptors
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: AKT1 CAV1 CMSS1 GNAI1 GNAI3 HTR1A HTR1D PDGFRB	2 interactors: GYG1 S1PR1
Entrez ID		1901	84319
HPRD ID		03578	11351
Ensembl ID		ENSG00000170989	ENSG00000184220
Uniprot IDs		P21453	D3DN44 Q9BQ75
PDB IDs		3V2W 3V2Y
Enriched GO Terms of Interacting Partners?		Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Vasoconstriction G-protein Coupled Receptor Signaling Pathway Wound Healing Response To Wounding Cell Surface Receptor Signaling Pathway Regulation Of Blood Vessel Size Regulation Of Tube Size Blood Coagulation Hemostasis Serotonin Receptor Signaling Pathway Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Body Fluid Levels Regulation Of Ion Transport Regulation Of Behavior Platelet Activation Positive Regulation Of Ion Transport Vesicle Organization Signal Transduction Nitric Oxide Metabolic Process Positive Regulation Of Vasoconstriction Response To Hyperoxia Reactive Nitrogen Species Metabolic Process Response To Fluid Shear Stress Signaling Regulation Of Nitric-oxide Synthase Activity Cell Communication Membrane Organization Response To Stress Regulation Of Lipid Metabolic Process Blood Circulation Response To Hormone Negative Regulation Of Ion Transmembrane Transport Vesicle Fusion Negative Regulation Of Transmembrane Transport Regulation Of Vasoconstriction Regulation Of Nitric Oxide Biosynthetic Process Cellular Response To Stimulus Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Ion Transmembrane Transport T Cell Costimulation Regulation Of Oxidoreductase Activity Organelle Fusion Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Fatty Acid Metabolic Process Regulation Of Endothelial Cell Proliferation Positive Regulation Of Reactive Oxygen Species Metabolic Process	Cardiac Muscle Tissue Growth Involved In Heart Morphogenesis Growth Involved In Heart Morphogenesis Sphingosine-1-phosphate Signaling Pathway Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Actin Filament Bundle Assembly Blood Vessel Maturation Glycogen Catabolic Process Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G-protein Coupled Signaling Pathway T Cell Migration Polysaccharide Catabolic Process Glycogen Biosynthetic Process Heart Trabecula Morphogenesis Lymphocyte Migration Cellular Carbohydrate Catabolic Process Positive Regulation Of Positive Chemotaxis Cardiac Muscle Tissue Growth Regulation Of Bone Resorption Cellular Polysaccharide Biosynthetic Process Polysaccharide Biosynthetic Process Regulation Of Bone Remodeling Lamellipodium Assembly Trabecula Morphogenesis Lamellipodium Organization Cardiac Muscle Tissue Morphogenesis Transmission Of Nerve Impulse Positive Regulation Of Smooth Muscle Cell Proliferation Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Glycogen Metabolic Process Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Regulation Of Stress Fiber Assembly Muscle Tissue Morphogenesis Actin Cytoskeleton Reorganization Regulation Of Tissue Remodeling Muscle Organ Morphogenesis Regulation Of Bone Mineralization Endothelial Cell Differentiation Polysaccharide Metabolic Process Endothelium Development Organ Growth Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Chemotaxis Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Behavior Energy Reserve Metabolic Process Regulation Of Chemotaxis Glucose Metabolic Process Developmental Growth Involved In Morphogenesis G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Carbohydrate Biosynthetic Process Carbohydrate Catabolic Process
Tagcloud ?		148a accordingly adjacent carcinoma downregulated downregulation hepatocellular hepg2 inhibitory interfering invasion malignancies markedly microrna mimics mir negatively never notably numerous phosphate restoration reversed sipr1 sphingosine suppressor transfection upregulation whose
Tagcloud (Difference) ?		148a accordingly adjacent carcinoma downregulated downregulation hepatocellular hepg2 inhibitory interfering invasion malignancies markedly microrna mimics mir negatively never notably numerous phosphate restoration reversed sipr1 sphingosine suppressor transfection upregulation whose
Tagcloud (Intersection) ?