DPYSL2 and DPYSL4

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		DPYSL2	DPYSL4
Gene Name		dihydropyrimidinase-like 2	dihydropyrimidinase-like 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Cytosol Microtubule Membrane Dendrite Growth Cone Neuronal Cell Body Terminal Bouton Extracellular Vesicular Exosome	Cytosol
	Molecular Function	Dihydropyrimidinase Activity Protein Binding Protein Kinase Binding	Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Cyclic Amides
	Biological Process	Response To Amphetamine Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Catabolic Process Endocytosis Cytoskeleton Organization Signal Transduction Nervous System Development Axon Guidance Regulation Of Neuron Projection Development Positive Regulation Of Glutamate Secretion Spinal Cord Development Olfactory Bulb Development Response To Cocaine Response To Drug Synaptic Vesicle Transport	Pyrimidine Nucleobase Catabolic Process Nervous System Development Axon Guidance
Pathways		Axon guidance Semaphorin interactions L1CAM interactions CRMPs in Sema3A signaling Recycling pathway of L1	Axon guidance Semaphorin interactions CRMPs in Sema3A signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: AP2A1 CRMP1 DISC1 DPYSL3 DPYSL4 DPYSL5 GORASP2 GSK3B LEF1 NUMB PLD2 ROCK1 TNIK TUBB	8 interactors: DPYSL2 DPYSL5 PTPRO RBPMS SH3GL1 SH3GL2 SH3GL3 TRIP13
Entrez ID		1808	10570
HPRD ID		03914	07463
Ensembl ID		ENSG00000092964	ENSG00000151640
Uniprot IDs		Q16555 Q59GB4	D3DRG7 O14531
PDB IDs		2GSE 2VM8
Enriched GO Terms of Interacting Partners?		Pyrimidine Nucleobase Catabolic Process Chemotaxis Axon Guidance Movement Of Cell Or Subcellular Component Generation Of Neurons Cell Morphogenesis Involved In Differentiation Neurogenesis Locomotion Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Morphogenesis Cell Morphogenesis Neuron Differentiation Nervous System Development Cell Projection Organization Neuron Projection Development Pyrimidine Nucleobase Metabolic Process Cell Projection Morphogenesis Cell Part Morphogenesis Neuron Development Cell Development Response To External Stimulus Cell Differentiation System Development Anatomical Structure Morphogenesis Multicellular Organismal Development Regulation Of Cell Development Anatomical Structure Development Positive Regulation Of Cell Development Response To Stimulus Regulation Of Cell Differentiation Wnt Signaling Pathway Developmental Process Telencephalon Development Canonical Wnt Signaling Pathway Cytoskeleton Organization Forebrain Neuroblast Division Neural Precursor Cell Proliferation Regulation Of Neurogenesis Regulation Of Cellular Component Organization Regulation Of Neuron Projection Development Regulation Of Epithelial Cell Differentiation Positive Regulation Of Neurogenesis Positive Regulation Of Cell Differentiation Forebrain Development Somatic Stem Cell Division Cell Surface Receptor Signaling Pathway Organelle Organization Regulation Of Cell Projection Organization	Pyrimidine Nucleobase Catabolic Process Axon Guidance Axonogenesis Nervous System Development Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Endocytosis Cell Morphogenesis Involved In Differentiation Pyrimidine Nucleobase Metabolic Process Neuron Projection Development Cell Projection Morphogenesis Anatomical Structure Development Cell Part Morphogenesis Cell Development Neuron Development Central Nervous System Development Developmental Process Cell Morphogenesis Neuron Differentiation Cell Projection Organization Slit Diaphragm Assembly Locomotion Synaptic Vesicle Transport System Development Negative Regulation Of Retinal Ganglion Cell Axon Guidance Vesicle-mediated Transport Cellular Response To Stimulus Movement Of Cell Or Subcellular Component Generation Of Neurons Multicellular Organismal Development Neurogenesis Regulation Of Retinal Ganglion Cell Axon Guidance Positive Regulation Of Glutamate Secretion Response To External Stimulus Negative Regulation Of Glomerular Filtration Establishment Of Vesicle Localization Signal Transduction Vesicle Localization Cell Differentiation Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Signaling Response To Stimulus Cell Communication Positive Regulation Of Amino Acid Transport Regulation Of Cellular Process Regulation Of Glutamate Secretion Regulation Of Glomerular Filtration Positive Regulation Of SMAD Protein Import Into Nucleus
Tagcloud ?		24months 2de 8months astrocytic avenues coactosin creatine diamond dihydropyrimidinase dynamin e693delta glutamic glyoxalase illuminate isocitrate littermates oligomers pea phosphoprotein phosphoproteins possessed presumed profilin ruby sh3 sypro transgenic triphosphatase vacuolar
Tagcloud (Difference) ?		24months 2de 8months astrocytic avenues coactosin creatine diamond dihydropyrimidinase dynamin e693delta glutamic glyoxalase illuminate isocitrate littermates oligomers pea phosphoprotein phosphoproteins possessed presumed profilin ruby sh3 sypro transgenic triphosphatase vacuolar
Tagcloud (Intersection) ?