DOCK3 and KHDRBS1

Number of citations of the paper that reports this interaction (PMID 22745667)
1

Data Source:
BioGRID (unspecified method)

		DOCK3	KHDRBS1
Gene Name		dedicator of cytokinesis 3	KH domain containing, RNA binding, signal transduction associated 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Nucleus Nucleoplasm Cytoplasm Membrane Grb2-Sos Complex
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding SH3 Domain Binding	DNA Binding RNA Binding SH3/SH2 Adaptor Activity Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding Protein Complex Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity	G2/M Transition Of Mitotic Cell Cycle Transcription, DNA-templated MRNA Processing Cell Cycle Arrest Signal Transduction Cell Surface Receptor Signaling Pathway Cell Proliferation Positive Regulation Of Signal Transduction Regulation Of Protein Stability Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Translational Initiation Regulation Of RNA Export From Nucleus Positive Regulation Of RNA Export From Nucleus
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Height ( 20881960)
Protein-Protein Interactions		5 interactors: CALM1 CRK KHDRBS1 PSEN1 PSEN2	109 interactors: ABI2 ACTB AGO1 AHI1 AMPH APBB1 ARHGEF4 ARHGEF9 AZIN1 BAIAP2L1 BTK BZRAP1 CBL CD2AP CDK1 CIRBP CREB3L3 CREBBP CRK CRKL CSK DDX5 DHX9 DLG1 DLG2 DLG3 DLG4 DNMBP DOCK2 DOCK3 EFEMP1 EMG1 FGR FNBP4 FRK FYN GAS7 GPHN GRAP GRAP2 GRB2 HCK HNRNPK INSR ITK ITSN1 ITSN2 JAK3 KHDRBS3 LCK LYN MAPK1 MIA2 MPP6 MYO1C MYO7A NCF1 NCK1 NCK2 NCKIPSD NPHP1 OSTF1 PACSIN1 PIK3R1 PIK3R3 PLCG1 PLCG2 POT1 PPP1R13B PRMT1 PSTPIP1 PTBP2 PTK6 PTPN6 RALY RAPSN RASA1 RBFOX2 RBM7 RBMX RUSC2 SASH1 SCG5 SH3PXD2A SH3YL1 SKAP2 SMAD2 SMARCA2 SNX30 SNX9 SORBS1 SPATA13 SRC SSFA2 STAT3 STUB1 TBL1X TJP1 TNFSF11 TUBB3 U2AF2 UBA52 UBASH3B VAV1 WBP4 YES1 YTHDC1 ZBTB7A ZDHHC6
Entrez ID		1795	10657
HPRD ID		10341	03926
Ensembl ID		ENSG00000088538	ENSG00000121774
Uniprot IDs		Q8IZD9	Q07666
PDB IDs			2XA6 3QHE
Enriched GO Terms of Interacting Partners?		Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Amyloid Precursor Protein Catabolic Process Cell Activation Beta-amyloid Metabolic Process Amyloid Precursor Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Kinase Activity Membrane Protein Ectodomain Proteolysis Notch Receptor Processing Regulation Of Kinase Activity Neurotrophin TRK Receptor Signaling Pathway Regulation Of Protein Metabolic Process Neurotrophin Signaling Pathway Regulation Of Immune Response Regulation Of Epidermal Growth Factor-activated Receptor Activity Endoplasmic Reticulum Calcium Ion Homeostasis Immune Response-activating Cell Surface Receptor Signaling Pathway Dorsal/ventral Neural Tube Patterning Positive Regulation Of Coagulation Regulation Of Protein Phosphorylation Membrane Protein Proteolysis Negative Regulation Of Protein Phosphorylation Brain Morphogenesis Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Signaling Cell Surface Receptor Signaling Pathway Immune Response Regulation Of Cellular Amino Acid Metabolic Process Negative Regulation Of Phosphorylation Regulation Of Immune System Process Regulation Of Phosphorylation Thymus Development Neural Tube Patterning Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Metabolic Process T Cell Activation Involved In Immune Response Activation Of MAPKK Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Kinase Activity Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Kinase Activity Positive Regulation Of Catalytic Activity Regulation Of Cellular Ketone Metabolic Process Regulation Of ERBB Signaling Pathway Somitogenesis Positive Regulation Of Transferase Activity	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Fc Receptor Signaling Pathway Signaling Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Communication Peptidyl-tyrosine Autophosphorylation Innate Immune Response Signal Transduction Immune Response-regulating Signaling Pathway Immune Response Endocytosis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Fc-gamma Receptor Signaling Pathway Locomotion Movement Of Cell Or Subcellular Component Cellular Response To Stimulus Positive Regulation Of Metabolic Process Cell Surface Receptor Signaling Pathway Defense Response Positive Regulation Of Immune Response Regulation Of Immune System Process Cellular Response To Peptide Hormone Stimulus Neurotrophin TRK Receptor Signaling Pathway Phagocytosis Cellular Response To Peptide Positive Regulation Of Immune System Process Neurotrophin Signaling Pathway Positive Regulation Of Signal Transduction Cellular Response To Growth Factor Stimulus Regulation Of Immune Response Epidermal Growth Factor Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Growth Factor Antigen Receptor-mediated Signaling Pathway Cell Differentiation Regulation Of Catalytic Activity Regulation Of Signal Transduction Peptidyl-tyrosine Phosphorylation Regulation Of Cellular Component Organization Immune System Process Response To Stimulus Regulation Of Signaling Cell Projection Organization Intracellular Signal Transduction Cellular Response To Organic Substance Regulation Of Metabolic Process
Tagcloud ?		apterous basket bsk counterpart cytokinesis dedicator discs dock1 dock11 driver drosophila duolink gal4 imaginal immunoblot jnk lacz ligation pannir pjnk proximity puckered rac1 spg split sponge thorax wing
Tagcloud (Difference) ?		apterous basket bsk counterpart cytokinesis dedicator discs dock1 dock11 driver drosophila duolink gal4 imaginal immunoblot jnk lacz ligation pannir pjnk proximity puckered rac1 spg split sponge thorax wing
Tagcloud (Intersection) ?