DBN1 and SUPT5H

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		DBN1	SUPT5H
Gene Name		drebrin 1	suppressor of Ty 5 homolog (S. cerevisiae)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Gap Junction Cell Cortex Actin Cytoskeleton Dendrite Actomyosin	Nucleus Nucleoplasm DSIF Complex
	Molecular Function	Actin Binding Protein Binding Profilin Binding	Chromatin Binding Protein Binding Enzyme Binding Poly(A) RNA Binding Protein Heterodimerization Activity
	Biological Process	Actin Filament Organization Cell Communication By Chemical Coupling Cell Communication By Electrical Coupling Maintenance Of Protein Location In Cell Regulation Of Neuronal Synaptic Plasticity Regulation Of Dendrite Development Neural Precursor Cell Proliferation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Remodeling DNA-templated Transcription, Elongation Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping Cell Cycle Response To Organic Substance Gene Expression Viral Process Positive Regulation Of Macroautophagy Negative Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of DNA-templated Transcription, Elongation Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Viral Transcription
Pathways			Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription Abortive elongation of HIV-1 transcript in the absence of Tat mRNA Capping HIV Infection Formation of the Early Elongation Complex Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery RNA Pol II CTD phosphorylation and interaction with CE RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle Pausing and recovery of Tat-mediated HIV elongation Formation of RNA Pol II elongation complex HIV elongation arrest and recovery HIV Life Cycle RNA Pol II CTD phosphorylation and interaction with CE Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex HIV Transcription Elongation Transcription of the HIV genome RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Activated partial thromboplastin time ( 22703881)
Protein-Protein Interactions		24 interactors: ACD BAK1 BTRC CDK2AP2 DNMBP DUSP23 FHL1 HOMER2 MAP1LC3B MAPK6 MEST NIPBL NUDT21 NUDT3 PFN1 POT1 SNUPN SUPT5H TAB1 TERF1 TINF2 TPT1 UBE2D3 ZNF598	37 interactors: C9orf78 CCNH CCNT1 CCNT2 CDK7 CDK9 CSNK2A1 DBN1 DCAF6 GTF3C1 H2AFX HTATSF1 IK IKBKG LMAN2 MAML3 MNAT1 PCBD1 PHYHIP PIN1 PNO1 POLR2A PPIA PPP2R2D PRMT1 PRMT5 SAP30BP SIK1 SNX4 SSBP3 SUPT4H1 TERF1 XRCC5 ZBTB3 ZFYVE9 ZNF496 ZNF512B
Entrez ID		1627	6829
HPRD ID		00545	03655
Ensembl ID		ENSG00000113758	ENSG00000196235
Uniprot IDs		F8W9Z3 Q16643	O00267
PDB IDs			2DO3 2E6Z 2E70 3H7H 4L1U
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Telomere Assembly Negative Regulation Of DNA Replication Regulation Of Telomerase Activity Telomere Maintenance Regulation Of Chromosome Organization Negative Regulation Of Chromosome Organization Positive Regulation Of Organelle Organization Negative Regulation Of DNA Metabolic Process Telomere Maintenance Via Telomere Lengthening Regulation Of DNA Replication Positive Regulation Of DNA Metabolic Process Regulation Of DNA Biosynthetic Process Protein Localization To Chromosome, Telomeric Region Telomere Capping Regulation Of Organelle Organization Negative Regulation Of Biosynthetic Process Positive Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomerase Activity Positive Regulation Of Telomere Maintenance Negative Regulation Of Cellular Metabolic Process Homeostatic Process Positive Regulation Of DNA Biosynthetic Process RNA-dependent DNA Replication Regulation Of Cellular Component Organization Negative Regulation Of DNA Biosynthetic Process Chromosome Organization Positive Regulation Of Cellular Metabolic Process DNA Metabolic Process Positive Regulation Of Catalytic Activity Protein Localization To Chromosome Tube Development Positive Regulation Of Metabolic Process Tube Morphogenesis Limb Morphogenesis Regulation Of Catalytic Activity Limb Development Positive Regulation Of Viral Transcription Negative Regulation Of Protein ADP-ribosylation SnRNA Import Into Nucleus Diphosphoinositol Polyphosphate Catabolic Process Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Diadenosine Polyphosphate Catabolic Process Organelle Organization Cellular Component Assembly	Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Viral Process Transcription, DNA-templated RNA Biosynthetic Process DNA-templated Transcription, Elongation Positive Regulation Of Viral Transcription Viral Process Cellular Macromolecule Biosynthetic Process Regulation Of Viral Transcription Macromolecule Biosynthetic Process Regulation Of Viral Process Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process DNA-templated Transcription, Initiation Biosynthetic Process Regulation Of Gene Expression Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Cell Cycle Regulation Of Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process 7-methylguanosine MRNA Capping 7-methylguanosine RNA Capping Transcription From RNA Polymerase II Promoter Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Transcription-coupled Nucleotide-excision Repair Positive Regulation Of Metabolic Process Cell Cycle Cellular Metabolic Process Nucleotide-excision Repair, DNA Damage Removal Negative Regulation Of Gene Expression, Epigenetic Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter
Tagcloud ?			19q13 aa acidic argues consensus differ end family homologue lacks like map maps member near q repeat respond ryanodine seven signals similarity spt5 spt6 terminus unlike w yeast
Tagcloud (Difference) ?			19q13 aa acidic argues consensus differ end family homologue lacks like map maps member near q repeat respond ryanodine seven signals similarity spt5 spt6 terminus unlike w yeast
Tagcloud (Intersection) ?