DAB1 and PCDH18

Number of citations of the paper that reports this interaction (PMID 11716507)
8

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		DAB1	PCDH18
Gene Name		Dab, reelin signal transducer, homolog 1 (Drosophila)	protocadherin 18
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Brush Border Postsynaptic Density Membrane Neuron Projection Neuronal Cell Body Apical Part Of Cell Perinuclear Region Of Cytoplasm	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Phosphatidylinositol 3-kinase Binding	Calcium Ion Binding
	Biological Process	Negative Regulation Of Cell Adhesion Small GTPase Mediated Signal Transduction Midgut Development Adult Walking Behavior Dendrite Development Ventral Spinal Cord Development Cerebellum Structural Organization Cerebral Cortex Radially Oriented Cell Migration Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Radial Glia Guided Migration Of Purkinje Cell Response To Drug Positive Regulation Of Neuron Differentiation Positive Regulation Of Protein Kinase Activity Negative Regulation Of JAK-STAT Cascade Negative Regulation Of Astrocyte Differentiation Negative Regulation Of Axonogenesis Golgi Localization Lateral Motor Column Neuron Migration	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Brain Development
Pathways
Drugs
Diseases
GWAS		Bulimia nervosa ( 23568457) Immune reponse to smallpox (secreted IL-10) ( 22610502) Kawasaki disease ( 21221998) Pubertal anthropometrics ( 23449627)	Adverse response to radiation therapy ( 23719583) Obesity-related traits ( 23251661) Retinopathy in non-diabetics ( 23393555) Temperament ( 22832960)
Protein-Protein Interactions		73 interactors: APLP1 APLP2 APP ARID5A BHLHE40 C1orf94 CDK5 CDK6 CIART CLASRP CRK CRKL DAB2IP DAZAP2 ERBB2 ERBB3 FAM103A1 FAM168A HMBOX1 HNRNPLL HYAL3 INPP5D ITGB2 ITGB3 ITGB5 ITGB7 KRTAP19-5 KRTAP19-7 KRTAP8-1 LDLR LGALS9B LGALS9C LNX1 LRP1 LRP2 LRP8 MAGED1 MBNL1 MBNL3 MYO6 NAF1 PAFAH1B1 PCDH18 PIN1 PLCG1 POGZ PPIG PRR20A PTPN11 RBFOX1 RBFOX2 RELN RHOXF2 ROR2 SERF2 SIAH1 SIRPB1 SMAP2 SNRPB SRC STRBP TCEA2 TCEANC TMTC3 TOLLIP USP53 VENTX VLDLR WDYHV1 ZBTB32 ZC3H10 ZCCHC10 ZNF488	1 interactors: DAB1
Entrez ID		1600	54510
HPRD ID		04582	12205
Ensembl ID		ENSG00000173406	ENSG00000189184
Uniprot IDs		O75553	D6RIG4 Q9HCL0
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Metabolic Process Multicellular Organismal Development Regulation Of Phosphorus Metabolic Process Positive Regulation Of Transferase Activity Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Regulation Of Protein Kinase Activity Regulation Of Phosphorylation Reelin-mediated Signaling Pathway Positive Regulation Of Protein Modification Process Developmental Process Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Central Nervous System Development Positive Regulation Of Protein Phosphorylation Anatomical Structure Development Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Gene Expression Positive Regulation Of Phosphorylation Positive Regulation Of Metabolic Process Nervous System Development Brain Development Regulation Of Cellular Protein Metabolic Process Gliogenesis Regulation Of Protein Metabolic Process Head Development Anatomical Structure Morphogenesis Response To External Stimulus Cell Surface Receptor Signaling Pathway Forebrain Development System Development Cell Differentiation Movement Of Cell Or Subcellular Component Negative Regulation Of Cellular Metabolic Process Organ Development Wound Healing Immune System Process Layer Formation In Cerebral Cortex Locomotion Neuron Projection Morphogenesis Regulation Of RNA Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Signaling Endocytosis MRNA Processing Neurogenesis Cerebral Cortex Radial Glia Guided Migration	Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Cerebellum Structural Organization Lateral Motor Column Neuron Migration Spinal Cord Motor Neuron Migration Radial Glia Guided Migration Of Purkinje Cell Golgi Localization Negative Regulation Of Astrocyte Differentiation Midgut Development Anatomical Structure Arrangement Negative Regulation Of JAK-STAT Cascade Cell Migration In Hindbrain Regulation Of Astrocyte Differentiation Negative Regulation Of Glial Cell Differentiation Adult Walking Behavior Cerebellum Morphogenesis Hindbrain Morphogenesis Ventral Spinal Cord Development Negative Regulation Of Axonogenesis Cerebral Cortex Radially Oriented Cell Migration Regulation Of Glial Cell Differentiation Cerebral Cortex Cell Migration Regulation Of JAK-STAT Cascade Telencephalon Cell Migration Negative Regulation Of Cell Morphogenesis Involved In Differentiation Forebrain Cell Migration Regulation Of Gliogenesis Spinal Cord Development Adult Locomotory Behavior Cerebellum Development Negative Regulation Of Neuron Projection Development Metencephalon Development Digestive Tract Development Negative Regulation Of Cell Projection Organization Dendrite Development Digestive System Development Regulation Of Axonogenesis Cerebral Cortex Development Adult Behavior Neuron Migration Hindbrain Development Negative Regulation Of Neuron Differentiation Pallium Development Negative Regulation Of Cell Adhesion Locomotory Behavior Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Telencephalon Development Negative Regulation Of Neurogenesis Positive Regulation Of Neuron Differentiation Negative Regulation Of Cell Development
Tagcloud ?		assist cajal connections cortical d1x dieker disabled doublecortn dubbed dysplasias hydrolase instructs lis1 lissencephaly malformation marginal miller neuregulin neurotrophic neurotrophin p35 plate preplate radial reelin retzius tangential tbr thalamocortical
Tagcloud (Difference) ?		assist cajal connections cortical d1x dieker disabled doublecortn dubbed dysplasias hydrolase instructs lis1 lissencephaly malformation marginal miller neuregulin neurotrophic neurotrophin p35 plate preplate radial reelin retzius tangential tbr thalamocortical
Tagcloud (Intersection) ?