CTNND2 and LRRC7

Number of citations of the paper that reports this interaction (PMID 11729199)
18

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		CTNND2	LRRC7
Gene Name		catenin (cadherin-associated protein), delta 2	leucine rich repeat containing 7
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Adherens Junction Perikaryon	Cytoplasm Postsynaptic Density Cell Junction Postsynaptic Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Morphogenesis Of A Branching Structure Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Adhesion Signal Transduction Multicellular Organismal Development Learning Single Organismal Cell-cell Adhesion Regulation Of Synaptic Plasticity
Pathways
Drugs
Diseases
GWAS		Myopia (pathological) ( 21095009)	Attention deficit hyperactivity disorder ( 21784300) Hypertension risk in short sleep duration ( 22322875) Obesity-related traits ( 23251661) Orofacial clefts ( 22419666)
Protein-Protein Interactions		18 interactors: ABL1 ATN1 CDH1 CDH2 CTNNB1 CTTN ERBB2IP FYN LCK LNX1 LRRC7 MAGI2 NUDT21 PDZD2 PSEN1 PSEN2 SPHK1 TTR	11 interactors: ACTN2 ACTN4 BAI1 CAMK2A CAMK2G CDH2 CNKSR2 CTNND2 HOMEZ NQO2 TOR1A
Entrez ID		1501	57554
HPRD ID		09181	09930
Ensembl ID		ENSG00000169862	ENSG00000033122
Uniprot IDs		B4DRK2 E7EPC8 Q9UQB3	Q96NW7
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Adhesion Single Organismal Cell-cell Adhesion Negative Regulation Of Signal Transduction Regulation Of Cell Differentiation T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Negative Regulation Of Signaling Antigen Receptor-mediated Signaling Pathway Neurogenesis Cell Migration Thymus Development Leukocyte Cell-cell Adhesion Nervous System Development Locomotion Homotypic Cell-cell Adhesion Cell Motility Central Nervous System Development Regulation Of Apoptotic Process Movement Of Cell Or Subcellular Component Lymphocyte Activation Regulation Of Neurogenesis Regulation Of Cell Death Generation Of Neurons Regulation Of Signal Transduction Adherens Junction Organization Brain Development Negative Regulation Of Apoptotic Signaling Pathway Leukocyte Activation Head Development Positive Regulation Of Intracellular Signal Transduction T Cell Receptor Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of Cell Development Regulation Of Signaling Positive Regulation Of Cell Differentiation Cell Development Immune Response-activating Cell Surface Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Programmed Cell Death Cellular Component Assembly Cellular Response To Growth Factor Stimulus Regulation Of Cellular Component Organization System Development Response To Growth Factor Negative Regulation Of Cell Death Leukocyte Differentiation Apoptotic Process	Regulation Of Ion Transport Regulation Of Protein Localization To Cell Surface Regulation Of Cellular Response To Heat Positive Regulation Of Ion Transport Cell Junction Assembly Cell-cell Junction Organization Synaptic Transmission Cell Adhesion Positive Regulation Of Transport Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Transporter Activity Regulation Of Synaptic Transmission Cellular Response To Heat Platelet Degranulation Cell-cell Signaling Positive Regulation Of Ion Transmembrane Transport Adherens Junction Organization Protein Oligomerization Cellular Component Assembly Positive Regulation Of Endocytosis Regulation Of Signaling Response To Heat Establishment Of Localization In Cell Protein Localization To Tight Junction Positive Regulation Of Synaptic Vesicle Endocytosis Cell-cell Adhesion Mediated By Cadherin Positive Regulation Of Pinocytosis ER-associated Misfolded Protein Catabolic Process Secretion By Cell Interferon-gamma-mediated Signaling Pathway Positive Regulation Of Sodium:proton Antiporter Activity Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Cellular Response To Interferon-gamma Nuclear Membrane Organization Wound Healing G1/S Transition Of Mitotic Cell Cycle Regulation Of Synaptic Plasticity Regulation Of Synaptic Vesicle Endocytosis Regulation Of Sodium:proton Antiporter Activity Microspike Assembly Peroxisome Proliferator Activated Receptor Signaling Pathway Secretion Response To Interferon-gamma Cellular Localization Regulation Of Relaxation Of Cardiac Muscle Regulation Of Endocytosis Response To Temperature Stimulus Regulation Of Calcium Ion Transport Response To Wounding
Tagcloud ?		16p11 17q21 2p21 acot7 autism auts2 cask categorised cnvs crebbp delineating exonic grm8 homozygous incidental instrumental iq kb med13l microdeletion morbid ndds neurodevelopmental nrxn3 omim pafah1b1 satb2 sizing undiagnosed
Tagcloud (Difference) ?		16p11 17q21 2p21 acot7 autism auts2 cask categorised cnvs crebbp delineating exonic grm8 homozygous incidental instrumental iq kb med13l microdeletion morbid ndds neurodevelopmental nrxn3 omim pafah1b1 satb2 sizing undiagnosed
Tagcloud (Intersection) ?