CRYM and C7orf25

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		CRYM	C7orf25
Gene Name		crystallin, mu	chromosome 7 open reading frame 25
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Extracellular Vesicular Exosome
	Molecular Function	Transcription Corepressor Activity Protein Homodimerization Activity Thiomorpholine-carboxylate Dehydrogenase Activity NADP Binding Thyroid Hormone Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Sensory Perception Of Sound Thyroid Hormone Metabolic Process Oxidation-reduction Process Thyroid Hormone Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: C7orf25 CDC37 TERF1	18 interactors: BRD4 CEP70 CRYM DACT1 EZH2 FRA10AC1 FYN FZR1 HAP1 HEXDC MTOR NGEF PTN RASSF1 RPL36AL SF3B2 TARS UBE2D1
Entrez ID		1428	79020
HPRD ID		08831	09861
Ensembl ID		ENSG00000103316	ENSG00000136197
Uniprot IDs		H9KVC2 Q14894	Q9BPX7
PDB IDs		2I99
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Loop Formation Age-dependent Telomere Shortening Telomere Maintenance Via Telomere Shortening Negative Regulation Of Telomere Maintenance Via Telomerase Replicative Cell Aging Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Nuclear Cell Cycle DNA Replication Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Microtubule Polymerization Regulation Of Telomerase Activity Regulation Of Cell Cycle Regulation Of Telomere Maintenance Regulation Of Interferon-gamma-mediated Signaling Pathway RNA-dependent DNA Replication Regulation Of Response To Interferon-gamma Negative Regulation Of DNA Biosynthetic Process Regulation Of Microtubule Polymerization Telomere Maintenance Via Telomere Lengthening Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Regulation Of Type I Interferon-mediated Signaling Pathway Positive Regulation Of Mitotic Nuclear Division Negative Regulation Of Chromosome Segregation Regulation Of DNA Biosynthetic Process Spindle Checkpoint Negative Regulation Of DNA Replication Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Cell Aging Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Cellular Protein Catabolic Process Telomere Maintenance Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Chromosome Organization Protein Stabilization Regulation Of Cytokine-mediated Signaling Pathway Negative Regulation Of DNA Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Mitotic Cell Cycle Negative Regulation Of Protein Catabolic Process	Regulation Of Cell Cycle Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Cell Cycle Process Regulation Of Protein Metabolic Process Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Cell Cycle Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Growth Factor Cellular Response To Stress Regulation Of Intracellular Signal Transduction Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Ubiquitination Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Protein Catabolic Process Mitotic Cell Cycle Positive Regulation Of Protein Metabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Signal Transduction Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Metabolic Process Regulation Of Cellular Component Organization Cellular Response To DNA Damage Stimulus Positive Regulation Of Cell Differentiation Posttranscriptional Regulation Of Gene Expression Regulation Of Cell Morphogenesis Regulation Of Protein Localization To Nucleus Regulation Of Cell Projection Organization Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Protein Modification Process Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Ubiquitination Positive Regulation Of Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Differentiation Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Division Positive Regulation Of Neurotrophin Production Regulation Of Carbohydrate Utilization Positive Regulation Of Nonmotile Primary Cilium Assembly Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Positive Regulation Of Cellular Protein Metabolic Process
Tagcloud ?		agt ass1 beadchip benjamini differentiates egr2 folr3 gja1 hochberg hrasls humanref illumina leiomyosarcoma lms lmss masp1 nlgn1 nlgn4x ostn rorb shmt1 slitrk4 tdo2 thbs1 tnnt1 tspan10 tspan7 uterine xrn2
Tagcloud (Difference) ?		agt ass1 beadchip benjamini differentiates egr2 folr3 gja1 hochberg hrasls humanref illumina leiomyosarcoma lms lmss masp1 nlgn1 nlgn4x ostn rorb shmt1 slitrk4 tdo2 thbs1 tnnt1 tspan10 tspan7 uterine xrn2
Tagcloud (Intersection) ?