COL8A2 and COL8A1

Number of citations of the paper that reports this interaction (PMID 12782141)
10

Data Source:
HPRD (in vitro)

		COL8A2	COL8A1
Gene Name		collagen, type VIII, alpha 2	collagen, type VIII, alpha 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Collagen Trimer Basement Membrane Endoplasmic Reticulum Lumen Extracellular Matrix	Extracellular Region Collagen Type VIII Trimer Endoplasmic Reticulum Lumen Extracellular Matrix Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding, Bridging
	Biological Process	Angiogenesis Single Organismal Cell-cell Adhesion Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Camera-type Eye Morphogenesis Epithelial Cell Proliferation	Angiogenesis Cell Adhesion Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Endodermal Cell Differentiation Camera-type Eye Morphogenesis Epithelial Cell Proliferation
Pathways		Collagen formation Collagen degradation Integrin cell surface interactions Collagen biosynthesis and modifying enzymes Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures	Collagen formation Collagen degradation Integrin cell surface interactions Collagen biosynthesis and modifying enzymes Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures
Drugs
Diseases
GWAS		Corneal structure ( 23291589)	Age-related macular degeneration ( 20385826 23455636)
Protein-Protein Interactions		2 interactors: COL8A1 SGTA	20 interactors: ADAMTSL4 COL8A2 CREB5 EFEMP2 INCA1 ITGA1 ITGA2 KLHL12 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP26-1 KRTAP4-12 KRTAP9-2 NOTCH2NL REL SP4 UBQLN4 VAC14
Entrez ID		1296	1295
HPRD ID		08347	00372
Ensembl ID		ENSG00000171812	ENSG00000144810
Uniprot IDs		E9PP49 P25067	P27658
PDB IDs
Enriched GO Terms of Interacting Partners?		Endodermal Cell Differentiation Endoderm Formation Collagen Catabolic Process Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Endoderm Development Epithelial Cell Proliferation Multicellular Organismal Metabolic Process Extracellular Matrix Disassembly Positive Regulation Of Cell-substrate Adhesion Camera-type Eye Morphogenesis Formation Of Primary Germ Layer	Extracellular Matrix Organization Extracellular Structure Organization Positive Regulation Of Phosphatase Activity Positive Regulation Of Dephosphorylation Positive Regulation Of Collagen Binding
Tagcloud ?		acetylcysteine bl6 blotting c57 celltiter chop confocal corneal drinking dystrophy endothelial endothelium fecd fuchs glo grp78 h2o2 homozygous ingestion inos knock l450w luminescent nac polymegathism reagent thapsigargin unfolded untreated	bladder carcinogenic deregulation elucidates emodin epigenetic epigenetics fabp4 h3k27 h3k27me3 h3s10 hbp17 inc periodicals ph3ser10 rational repressed restore reverses reversing rgs4 situations specialized timp3 urb viii warrants wiley wnt5b
Tagcloud (Difference) ?		acetylcysteine bl6 blotting c57 celltiter chop confocal corneal drinking dystrophy endothelial endothelium fecd fuchs glo grp78 h2o2 homozygous ingestion inos knock l450w luminescent nac polymegathism reagent thapsigargin unfolded untreated	bladder carcinogenic deregulation elucidates emodin epigenetic epigenetics fabp4 h3k27 h3k27me3 h3s10 hbp17 inc periodicals ph3ser10 rational repressed restore reverses reversing rgs4 situations specialized timp3 urb viii warrants wiley wnt5b
Tagcloud (Intersection) ?