CST9L and SLC22A2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CST9L	SLC22A2
Gene Name		cystatin 9-like	solute carrier family 22 (organic cation transporter), member 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region	Plasma Membrane Integral Component Of Plasma Membrane Membrane Basolateral Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Cysteine-type Endopeptidase Inhibitor Activity	Steroid Binding Organic Cation Transmembrane Transporter Activity Choline Transmembrane Transporter Activity Quaternary Ammonium Group Transmembrane Transporter Activity
	Biological Process	Negative Regulation Of Endopeptidase Activity	Drug Transmembrane Transport Synaptic Transmission Neurotransmitter Secretion Body Fluid Secretion Organic Cation Transport Quaternary Ammonium Group Transport Choline Transport Ion Transmembrane Transport Neurotransmitter Biosynthetic Process Small Molecule Metabolic Process Histamine Transport Transmembrane Transport
Pathways			Na+/Cl- dependent neurotransmitter transporters Neurotransmitter Release Cycle Neurotransmitter Clearance In The Synaptic Cleft Organic cation transport Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Norepinephrine Neurotransmitter Release Cycle Abacavir transmembrane transport Organic cation/anion/zwitterion transport SLC-mediated transmembrane transport Abacavir transport and metabolism Transmission across Chemical Synapses
Drugs
Diseases
GWAS		Cystatin C ( 17903292)	Chronic kidney disease ( 20383146) Creatinine levels ( 20383145)
Protein-Protein Interactions		6 interactors: CCR5 KRTAP10-3 KRTAP10-9 NOTCH2NL SLC22A2 TAB2	9 interactors: AGO3 CST9L ETV5 EXT2 GTF2B HYAL3 LSM4 POU2AF1 SUMO2
Entrez ID		128821	6582
HPRD ID		16769	04008
Ensembl ID		ENSG00000101435	ENSG00000112499
Uniprot IDs		Q9H4G1	O15244
PDB IDs
Enriched GO Terms of Interacting Partners?		MAPK Cascade Signal Transduction By Phosphorylation Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Choline Transport Sarcoplasmic Reticulum Calcium Ion Transport Dendritic Cell Chemotaxis Neurotransmitter Biosynthetic Process Histamine Transport Quaternary Ammonium Group Transport Signaling Cell Communication Response To Cholesterol Dendritic Cell Migration Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Neurotransmitter Metabolic Process Drug Transmembrane Transport Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Sequestering Of Calcium Ion Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ammonium Transmembrane Transport Organic Cation Transport Drug Transport Entry Into Host Cell Calcium Ion Transport Into Cytosol Cytosolic Calcium Ion Transport Cell Surface Receptor Signaling Pathway Cell-cell Signaling Toll-like Receptor 5 Signaling Pathway Cellular Defense Response Toll-like Receptor 10 Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Chemokine-mediated Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway	Nitrogen Compound Metabolic Process Heparan Sulfate Proteoglycan Biosynthetic Process, Polysaccharide Chain Biosynthetic Process MRNA Catabolic Process Male Germ-line Stem Cell Asymmetric Division Glycosaminoglycan Metabolic Process RNA Catabolic Process Regulation Of Branching Involved In Mammary Gland Duct Morphogenesis Cellular Response To UV-B Skeletal Muscle Acetylcholine-gated Channel Clustering RNA Metabolic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Translation Involved In Gene Silencing By MiRNA
Tagcloud ?			4alpha ahn brush cyp2d2 cyp2d4 dme dmes fmo1 ggt1 handled hnf1a hnf4a massively mate1 metabolizing nfe2l2 nigam nqo2 nr3c1 oat1 oat3 oct1 oct2 pt slc47a1 wu
Tagcloud (Difference) ?			4alpha ahn brush cyp2d2 cyp2d4 dme dmes fmo1 ggt1 handled hnf1a hnf4a massively mate1 metabolizing nfe2l2 nigam nqo2 nr3c1 oat1 oat3 oct1 oct2 pt slc47a1 wu
Tagcloud (Intersection) ?