CNTFR and KRTAP4-12

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CNTFR	KRTAP4-12
Gene Name		ciliary neurotrophic factor receptor	keratin associated protein 4-12
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extrinsic Component Of Membrane Anchored Component Of Membrane Ciliary Neurotrophic Factor Receptor Complex CNTFR-CLCF1 Complex	Keratin Filament
	Molecular Function	Ciliary Neurotrophic Factor Receptor Activity Receptor Binding Cytokine Binding	Protein Binding
	Biological Process	Suckling Behavior Brainstem Development Signal Transduction Nervous System Development Sex Differentiation Positive Regulation Of Cell Proliferation Negative Regulation Of Neuron Apoptotic Process Skeletal Muscle Organ Development Ciliary Neurotrophic Factor-mediated Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: APPBP2 CLCF1 CNTF CRLF1 HN1L IL6ST KRTAP4-12 LIFR PLSCR1	107 interactors: ADAMTSL4 ALPP AQP1 ATG12 ATN1 BAHD1 BEX2 C10orf62 C19orf66 CATSPER1 CBX2 CCDC116 CCDC185 CCNK CDC42EP1 CHCHD3 CHIC2 CLDN2 CNNM3 CNTFR COL8A1 CRCT1 CREB5 CRY1 DBF4B DLK2 EIF4E2 FAM107A FAM27E3 FAM76B FBXL18 FBXW5 GLRX3 GNE GPATCH2L GPRIN2 GRAP2 HHEX HOXA1 HOXB9 IFI30 ILF3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP26-1 KRTAP3-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 LCE1B LCE2D LCE3E LCE4A LINGO1 LNX1 MAPKBP1 MEOX2 MRPL4 NOTCH2NL NPDC1 NUDT18 NUFIP2 OTX1 PCSK5 PDGFRB PFKL PHLDA1 PLSCR1 PLSCR4 PNKP PRKAB2 PRR13 QPRT RERE RPS28 SLC25A10 SLC25A6 SMCP SPATA3 SPG7 SPRY2 TAP1 TBC1D16 TBC1D23 TCEB3B THAP10 THAP7 TOP3B TXNDC5 ZBTB16 ZNF165 ZNF20 ZNF250 ZNF408 ZNF415 ZNF417 ZNF426 ZNF439 ZNF440 ZNF581 ZNF638 ZNF655 ZNF764 ZSCAN26
Entrez ID		1271	83755
HPRD ID		00348	13941
Ensembl ID		ENSG00000122756	ENSG00000213416
Uniprot IDs		P26992	Q9BQ66
PDB IDs		1UC6
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Ciliary Neurotrophic Factor-mediated Signaling Pathway Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of JAK-STAT Cascade Regulation Of JAK-STAT Cascade Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Peptidyl-tyrosine Phosphorylation Leukemia Inhibitory Factor Signaling Pathway Oncostatin-M-mediated Signaling Pathway Response To Cytokine Positive Regulation Of Cell Proliferation Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Astrocyte Differentiation Cytokine-mediated Signaling Pathway Regulation Of Cellular Ketone Metabolic Process Cellular Response To Cytokine Stimulus Negative Regulation Of Neuron Apoptotic Process Regulation Of Cell Proliferation Negative Regulation Of Neuron Death Positive Regulation Of Protein Phosphorylation Regulation Of Astrocyte Differentiation Regulation Of Neuron Apoptotic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Phosphorylation Positive Regulation Of Glial Cell Differentiation Regulation Of Neuron Death Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Positive Regulation Of Gliogenesis Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Glial Cell Differentiation Positive Regulation Of Protein Metabolic Process Response To Organic Substance Positive Regulation Of Signal Transduction Regulation Of Cell Activation Positive Regulation Of Cellular Metabolic Process Regulation Of Phosphorylation Interleukin-11-mediated Signaling Pathway Regulation Of Signal Transduction Regulation Of Gliogenesis Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Regulation Of Cell Death Interleukin-27-mediated Signaling Pathway	Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process RNA Biosynthetic Process Transcription, DNA-templated Biosynthetic Process Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Metabolic Process Regulation Of RNA Metabolic Process Keratinization Anterior/posterior Pattern Specification Regulation Of Cellular Process Regulation Of Metabolic Process Cellular Process Keratinocyte Differentiation Embryo Development Phospholipid Scrambling Metanephric Glomerulus Vasculature Development Pattern Specification Process Metanephric Glomerulus Development Epidermal Cell Differentiation Epidermis Development Mitochondrion Organization Metabolic Process Forebrain Morphogenesis Transcription From RNA Polymerase II Promoter Glomerulus Vasculature Development Multicellular Organismal Development Organic Anion Transport Inner Ear Development Cell Migration Involved In Coronary Angiogenesis Hepatic Duct Development Abducens Nerve Formation Metanephric Mesenchymal Cell Migration Transepithelial Water Transport Renin Secretion Into Blood Stream Metanephric Descending Thin Limb Development DGDP Catabolic Process Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development
Tagcloud ?		acidic afgf albino bfgf ciliary college dystrophy fgf fgfr1 fibrillary gfap hybridizations igfr inherited injured minimize neurotrophic persisted photoreceptor prompt rcs retina royal slower subretinal surgeons trkb vicinity
Tagcloud (Difference) ?		acidic afgf albino bfgf ciliary college dystrophy fgf fgfr1 fibrillary gfap hybridizations igfr inherited injured minimize neurotrophic persisted photoreceptor prompt rcs retina royal slower subretinal surgeons trkb vicinity
Tagcloud (Intersection) ?