GSTO2 and MUM1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		GSTO2	MUM1
Gene Name		glutathione S-transferase omega 2	melanoma associated antigen (mutated) 1
Image
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome	Nucleus
	Molecular Function	Glutathione Transferase Activity Oxidoreductase Activity Glutathione Dehydrogenase (ascorbate) Activity Methylarsonate Reductase Activity	Protein Binding Nucleosome Binding
	Biological Process	Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Xenobiotic Metabolic Process L-ascorbic Acid Metabolic Process Small Molecule Metabolic Process Oxidation-reduction Process Cellular Response To Arsenic-containing Substance Glutathione Derivative Biosynthetic Process	DNA Repair Chromatin Organization
Pathways		Metabolism of vitamins and cofactors Defective CD320 causes methylmalonic aciduria Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective UGT1A4 causes hyperbilirubinemia Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Metabolic disorders of biological oxidation enzymes Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective AMN causes hereditary megaloblastic anemia 1 Defective UGT1A1 causes hyperbilirubinemia Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GGT1 causes Glutathionuria (GLUTH) Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GSS causes Glutathione synthetase deficiency (GSS deficiency) Defects in cobalamin (B12) metabolism Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective GIF causes intrinsic factor deficiency Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Glutathione conjugation Vitamin C (ascorbate) metabolism Defective MMAA causes methylmalonic aciduria type cblA Defective CUBN causes hereditary megaloblastic anemia 1 Phase II conjugation Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Defective TCN2 causes hereditary megaloblastic anemia Defects in vitamin and cofactor metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: MUM1 TFAP2A	6 interactors: CEP55 GOPC GSTO2 HIST2H3C MEOX2 PSMA3
Entrez ID		119391	84939
HPRD ID		13614	14789
Ensembl ID		ENSG00000065621	ENSG00000160953
Uniprot IDs		Q9H4Y5	J3KNX4 Q2TAK8
PDB IDs		3Q18 3Q19 3QAG	3PMI
Enriched GO Terms of Interacting Partners?		Optic Cup Structural Organization Positive Regulation Of Interleukin-13 Biosynthetic Process Cell Fate Commitment Optic Vesicle Morphogenesis Oculomotor Nerve Formation Positive Regulation Of Interleukin-10 Biosynthetic Process Positive Regulation Of Interleukin-4 Biosynthetic Process Positive Regulation Of Tooth Mineralization Oculomotor Nerve Development T-helper 17 Cell Lineage Commitment T-helper 17 Cell Differentiation Anterior Neuropore Closure Optic Cup Morphogenesis Involved In Camera-type Eye Development Negative Regulation Of Transcription By Competitive Promoter Binding Cornea Development In Camera-type Eye Lens Induction In Camera-type Eye Trigeminal Nerve Development Keratinocyte Development Positive Regulation Of Odontogenesis Cellular Response To Iron Ion T-helper Cell Lineage Commitment Positive Regulation Of Interleukin-2 Biosynthetic Process Positive Regulation Of Interleukin-13 Production CD4-positive Or CD8-positive, Alpha-beta T Cell Lineage Commitment Transcription From RNA Polymerase II Promoter Eyelid Development In Camera-type Eye Embryonic Body Morphogenesis Embryonic Camera-type Eye Formation Parasympathetic Nervous System Development Basement Membrane Organization Anatomical Structure Arrangement Positive Regulation Of Transcription From RNA Polymerase II Promoter Defense Response To Protozoan Positive Regulation Of Interleukin-4 Production Sympathetic Nervous System Development Regulation Of Interleukin-2 Biosynthetic Process T Cell Lineage Commitment Myeloid Dendritic Cell Differentiation Negative Regulation Of Signal Transduction Negative Regulation Of Toll-like Receptor Signaling Pathway Response To Protozoan Retina Layer Formation Myeloid Dendritic Cell Activation Positive T Cell Selection Lens Morphogenesis In Camera-type Eye T-helper Cell Differentiation Regulation Of Odontogenesis Negative Regulation Of Signaling Positive Regulation Of Interleukin-10 Production Regulation Of Interleukin-4 Production	Cytoplasmic Sequestering Of CFTR Protein
Tagcloud ?			barr bcl6 blastoid ccnd1 cd10 cd20 cd5 clinicopathologic coexistence convincingly cooperate differentiating dlbcl entity epstein igh immunophenotypic mantle molecularly morphologic pitfall pleomorphic pose rearrangement rearrangements relapsed rendered sox11 thorough
Tagcloud (Difference) ?			barr bcl6 blastoid ccnd1 cd10 cd20 cd5 clinicopathologic coexistence convincingly cooperate differentiating dlbcl entity epstein igh immunophenotypic mantle molecularly morphologic pitfall pleomorphic pose rearrangement rearrangements relapsed rendered sox11 thorough
Tagcloud (Intersection) ?