CISH and MAP3K7CL

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CISH	MAP3K7CL
Gene Name		cytokine inducible SH2-containing protein	MAP3K7 C-terminal like
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Cytoplasm Cytosol Plasma Membrane	Nucleus Cytosol
	Molecular Function	Molecular_function Protein Kinase Inhibitor Activity Protein Binding	Protein Binding
	Biological Process	Regulation Of Cell Growth Negative Regulation Of Protein Kinase Activity Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Protein Ubiquitination Cytokine-mediated Signaling Pathway Intracellular Signal Transduction Negative Regulation Of JAK-STAT Cascade Negative Regulation Of Insulin Receptor Signaling Pathway JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Pathways		Cytokine Signaling in Immune system Growth hormone receptor signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: CSF2RB CSF3R EGFR EPOR ERBB2 ETV5 GHR HSPA6 IL2RB IL3RA KIT MAP3K7CL MYD88 PRKCA PRKCB PRKCQ PRLR SMAD2	6 interactors: AK8 CISH GPS2 KRT31 REL TAB3
Entrez ID		1154	56911
HPRD ID		03897	10764
Ensembl ID		ENSG00000114737	ENSG00000156265
Uniprot IDs		Q9NSE2	B0EVZ6 B0EVZ8 P57077
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Organic Substance Response To Organic Substance Cytokine-mediated Signaling Pathway Cell Surface Receptor Signaling Pathway Response To Cytokine Cellular Response To Cytokine Stimulus Cellular Response To Stimulus Signaling Cell Communication Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Signal Transduction Response To Stimulus Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Signal Transduction Protein Phosphorylation Phosphorylation Intracellular Signal Transduction Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Positive Regulation Of MAPK Cascade Histone H3-T6 Phosphorylation Erythropoietin-mediated Signaling Pathway Interleukin-3-mediated Signaling Pathway Immune Response-regulating Signaling Pathway Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cell Proliferation Positive Regulation Of Phosphorylation Peptidyl-tyrosine Phosphorylation Activation Of JAK2 Kinase Activity Regulation Of MAP Kinase Activity Negative Regulation Of Programmed Cell Death Cellular Response To Growth Factor Stimulus Positive Regulation Of Cellular Metabolic Process Peptidyl-amino Acid Modification Response To Growth Factor Chemotaxis Negative Regulation Of Cell Death Cellular Response To Erythropoietin Regulation Of MAPK Cascade Negative Regulation Of Insulin Receptor Signaling Pathway Regulation Of Cell Proliferation Regulation Of Signal Transduction Cellular Response To Interleukin-3 Epidermal Growth Factor Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway ERBB Signaling Pathway Cell Activation Immune System Process Fibroblast Growth Factor Receptor Signaling Pathway	I-kappaB Kinase/NF-kappaB Signaling JNK Cascade Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Regulation Of Intracellular Signal Transduction Intracellular Signal Transduction Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Regulation Of Protein Metabolic Process Negative Regulation Of Protein Kinase Activity MAPK Cascade Negative Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Signal Transduction By Phosphorylation Regulation Of MAP Kinase Activity Regulation Of Signal Transduction Negative Regulation Of Transferase Activity Negative Regulation Of Protein Phosphorylation Regulation Of Phosphorylation Positive Regulation Of Interleukin-12 Biosynthetic Process Regulation Of Signaling Negative Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Regulation Of Interleukin-12 Biosynthetic Process Negative Regulation Of Intracellular Signal Transduction JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Negative Regulation Of JAK-STAT Cascade Growth Hormone Receptor Signaling Pathway Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Response To Growth Hormone Stimulus Negative Regulation Of JNK Cascade Phosphorylation Inactivation Of MAPK Activity Negative Regulation Of Stress-activated MAPK Cascade Regulation Of Cellular Protein Metabolic Process Regulation Of MAPK Cascade Nucleoside Diphosphate Phosphorylation Negative Regulation Of Insulin Receptor Signaling Pathway Response To Growth Hormone Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway NIK/NF-kappaB Signaling Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Interleukin-12 Production Ventricular System Development
Tagcloud ?		adenocarcinomas applicable appropriately chromogenic clinicopathologic differentiating diffuse disagreement educated esophageal gastroesophageal her2 histologically ihc interobserver introduced junction oncogene pathologists positivity retrieved retrospectively scoring stained standardized trained validate variability
Tagcloud (Difference) ?		adenocarcinomas applicable appropriately chromogenic clinicopathologic differentiating diffuse disagreement educated esophageal gastroesophageal her2 histologically ihc interobserver introduced junction oncogene pathologists positivity retrieved retrospectively scoring stained standardized trained validate variability
Tagcloud (Intersection) ?