DMC1 and TRIM23

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		DMC1	TRIM23
Gene Name		DNA meiotic recombinase 1	tripartite motif containing 23
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Telomeric Region Condensed Nuclear Chromosome Nucleus Chromosome	Golgi Membrane Nucleus Lysosomal Membrane Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity	GTPase Activity Ubiquitin-protein Transferase Activity Protein Binding GTP Binding Enzyme Activator Activity Zinc Ion Binding Ligase Activity GDP Binding Identical Protein Binding
	Biological Process	Ovarian Follicle Development Oocyte Maturation Meiotic Nuclear Division Synapsis Reciprocal Meiotic Recombination Male Meiosis I Spermatogenesis Spermatid Development Female Gamete Generation	Small GTPase Mediated Signal Transduction Viral Process Protein Ubiquitination Positive Regulation Of Catalytic Activity
Pathways		Meiotic recombination
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: BRCA2 GORASP2 KCTD17 NIF3L1 PSMA3 RAD51 RAD54B RPA1 SDCBP TRIM23	137 interactors: AKTIP ANKRD36BP1 AQP1 ARFGAP1 ARHGEF3 ARNT2 ATPAF2 ATXN7 BAG1 C10orf10 C19orf57 C8orf33 CARD9 CCDC146 CCDC25 CDC20B CDR2 CFAP53 COX5B CREB5 CXCL14 CYTH1 CYTH2 DCX DMC1 DMRT3 DOCK2 EAF2 EXOC3-AS1 FAM103A1 FAM110A FAM133A FAM193B FAM208B FAM83A FAM90A1 FBF1 FHIT FLAD1 FLJ38668 FXR2 GATA2 GEM GGA2 GMCL1P1 GPANK1 GPKOW HAUS1 HOXB5 HSPB7 IQCE IQUB JOSD1 KAT5 KIFC3 KLHL42 KRT6A LGALS8 LINC00526 LINC01018 LMO2 LNX1 LOC729603 MDM2 MKRN3 MLH1 MORN4 MRPL4 MRPL45 MTFR2 NEK6 NFU1 NXT2 PHF1 PIAS2 PIK3R2 PITX1 PKP4 POLI POLL POM121 PPIL2 PPP1R18 PSMA1 RAD18 RIBC2 RNF126 RNF213 RNF32 RNF34 RSRC2 RTP5 SF1 SH2D4A SIAH1 SLC25A6 SMG9 SNAI1 SNAI2 SNRPB SORBS3 SPG21 STK19 SUMO1P1 TBC1D22B TMSB4X TNFAIP3 TRAF1 TRAIP TRIM27 TRIM29 TRIM31 TRIM32 TRIM42 TROAP TSG101 TSHZ3 TXNDC5 UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2H UBE2I UBE2U UBOX5 USP2 USP20 USP21 UTP23 WDR25 ZC2HC1C ZNF250 ZNF564 ZNF581
Entrez ID		11144	373
HPRD ID		04099	03449
Ensembl ID		ENSG00000100206	ENSG00000113595
Uniprot IDs		B4DMW6 Q14565	P36406
PDB IDs		1V5W 2ZJB 4HYY
Enriched GO Terms of Interacting Partners?		Double-strand Break Repair Via Homologous Recombination Recombinational Repair Mitotic Recombination Double-strand Break Repair Meiotic Nuclear Division Meiotic Cell Cycle DNA Recombinase Assembly DNA Recombination Cell Cycle Meiosis I DNA-dependent DNA Replication Cellular Response To DNA Damage Stimulus Cell Cycle Process DNA Repair Reciprocal Meiotic Recombination DNA Replication Cellular Response To Stress DNA Duplex Unwinding DNA Geometric Change DNA Damage Response, Signal Transduction By P53 Class Mediator Chromosome Organization Reproduction DNA Metabolic Process Signal Transduction In Response To DNA Damage Nucleotide-excision Repair Organelle Organization 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Signal Transduction By P53 Class Mediator Positive Regulation Of Metabolic Process Positive Regulation Of DNA Ligation Dihydrobiopterin Metabolic Process Cellular Response To Camptothecin Response To Ionizing Radiation Response To Camptothecin Positive Regulation Of Extracellular Vesicular Exosome Assembly G1/S Transition Of Mitotic Cell Cycle Protein-DNA Complex Assembly Positive Regulation Of Cellular Metabolic Process Regulation Of Extracellular Vesicular Exosome Assembly Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Mitotic Cell Cycle Replication Fork Protection Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Protein Homooligomerization Response To UV-C Substrate-dependent Cell Migration, Cell Extension Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Intracellular Signal Transduction	Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Cellular Protein Modification Process Cellular Protein Metabolic Process Regulation Of Protein Catabolic Process Proteolysis Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Apoptotic Process Programmed Cell Death Regulation Of Metabolic Process Cellular Response To Stress Positive Regulation Of Metabolic Process Cell Death Death Gene Expression RNA Biosynthetic Process Transcription, DNA-templated Negative Regulation Of RNA Biosynthetic Process Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Biosynthetic Process RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Response To Hypoxia Protein Metabolic Process Cellular Response To Decreased Oxygen Levels Regulation Of Transcription, DNA-templated Regulation Of Proteolysis Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Response To Oxygen Levels Regulation Of Cellular Protein Metabolic Process Nucleobase-containing Compound Metabolic Process
Tagcloud ?		abs beams bragg btg2 ccnb2 cdc25a cdc25c exo1 fen1 gadd45a gtse1 gy hle ifnb1 instantaneous karyotyping mdm4 mm2 passively prc1 protons pttg1 rpa1 siah1 tdr voxel xrcc2 xrcc3 xrcc6bp1	344r abrogated adaptor antiviral conjugation defense e3 ectopic embryo helicase ikkgamma innate irf3 k165 k27 lys mda5 modulator multipoints nemo polyubiquitination rig substantially tightly tlr3 tlrs toll triparite ubiquitin
Tagcloud (Difference) ?		abs beams bragg btg2 ccnb2 cdc25a cdc25c exo1 fen1 gadd45a gtse1 gy hle ifnb1 instantaneous karyotyping mdm4 mm2 passively prc1 protons pttg1 rpa1 siah1 tdr voxel xrcc2 xrcc3 xrcc6bp1	344r abrogated adaptor antiviral conjugation defense e3 ectopic embryo helicase ikkgamma innate irf3 k165 k27 lys mda5 modulator multipoints nemo polyubiquitination rig substantially tightly tlr3 tlrs toll triparite ubiquitin
Tagcloud (Intersection) ?