RPP14 and RPP25

Number of citations of the paper that reports this interaction (PMID 15096576)
35

Data Source:
HPRD (in vitro)

		RPP14	RPP25
Gene Name		ribonuclease P/MRP 14kDa subunit	ribonuclease P/MRP 25kDa subunit
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleoplasm Microtubule Organizing Center
	Molecular Function	RNA Binding Ribonuclease P Activity	Ribonuclease P Activity Protein Binding Poly(A) RNA Binding
	Biological Process	TRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	TRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: A2M ATP5B CAPZB DOCK7 EXOSC8 IGSF21 KMT2B LIMD1 MSH2 NOVA1 PKM POP4 POP5 PSME1 RPP25 RPP30 RPP38 RPP40 WIZ	7 interactors: POP1 POP4 POP5 POP7 RPP14 RPP38 TERF2IP
Entrez ID		11102	54913
HPRD ID		18001	15276
Ensembl ID		ENSG00000163684
Uniprot IDs		O95059	Q9BUL9
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Phosphodiester Bond Hydrolysis, Endonucleolytic RNA Phosphodiester Bond Hydrolysis TRNA Processing TRNA Metabolic Process NcRNA Metabolic Process Nucleic Acid Phosphodiester Bond Hydrolysis Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Negative Regulation Of Reciprocal Meiotic Recombination Negative Regulation Of Complement Activation, Lectin Pathway Ribonucleoprotein Complex Biogenesis Meiotic Mismatch Repair Establishment Of Neuroblast Polarity Mitotic DNA Damage Checkpoint Cellular Metabolic Process Mitotic DNA Integrity Checkpoint Gene Silencing Meiotic Gene Conversion Maintenance Of DNA Repeat Elements Positive Regulation Of Gene Silencing By MiRNA Generation Of Precursor Metabolites And Energy Signal Transduction By P53 Class Mediator Positive Regulation Of Nuclear Cell Cycle DNA Replication	RNA Phosphodiester Bond Hydrolysis, Endonucleolytic RNA Phosphodiester Bond Hydrolysis TRNA Processing TRNA Metabolic Process Nucleic Acid Phosphodiester Bond Hydrolysis NcRNA Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of DNA Recombination At Telomere TRNA 5'-leader Removal Sinoatrial Node Cell Development TRNA Catabolic Process Sinoatrial Node Cell Differentiation Protection From Non-homologous End Joining At Telomere Telomere Capping Protein Localization To Chromosome, Telomeric Region Sinoatrial Node Development Cellular Metabolic Process Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Double-strand Break Repair Via Homologous Recombination Cardiac Conduction System Development MRNA Cleavage Positive Regulation Of Receptor Recycling Regulation Of Telomere Maintenance Positive Regulation Of Interleukin-1 Beta Secretion Positive Regulation Of Interleukin-1 Secretion RNA-dependent DNA Replication Negative Regulation Of DNA Recombination Regulation Of Rac GTPase Activity Regulation Of Interleukin-1 Beta Secretion Regulation Of Double-strand Break Repair Regulation Of Cdc42 GTPase Activity Positive Regulation Of Interleukin-1 Beta Production Regulation Of Receptor Recycling Protein Localization To Chromosome Regulation Of Cdc42 Protein Signal Transduction Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Interleukin-1 Production Tumor Necrosis Factor-mediated Signaling Pathway Epithelial Cell-cell Adhesion Regulation Of Rac Protein Signal Transduction
Tagcloud ?			ana antinuclear autoantibodies autoantigen autoantigens besides centromere evolutionarily exosome fibrillarin homogenous hpop1 iif indirect mrp nucleolar pm reportedly rheumatic rnase rnp rpp38 sard specificities ssc th topoisomerase u3 vast
Tagcloud (Difference) ?			ana antinuclear autoantibodies autoantigen autoantigens besides centromere evolutionarily exosome fibrillarin homogenous hpop1 iif indirect mrp nucleolar pm reportedly rheumatic rnase rnp rpp38 sard specificities ssc th topoisomerase u3 vast
Tagcloud (Intersection) ?