COPS5 and MAP3K7

  • Number of citations of the paper that reports this interaction (PMID 20936779)
  • 48
  • Data Source:
  • BioGRID (two hybrid)

COPS5

MAP3K7

Gene Name COP9 signalosome subunit 5 mitogen-activated protein kinase kinase kinase 7
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 90 interactors: APCS ARFGAP1 ATRN BCL2L14 BCL3 C12orf10 C6orf203 CACNA1C CD93 CDKN1B CENPT CHUK COPS2 COPS3 COPS4 COPS6 COPS7A COPS8 CUL1 CUL2 CUL4A CUL5 DDB1 DDO ERN1 ESR1 F2RL1 GFER GFI1B GPS1 HAND2 HIF1A HNF4A HNF4G HTR6 HUS1 ITGB2 JUN JUND LOC284014 MAP2K2 MAP3K11 MAP3K3 MAP3K7 MAP4K3 MAP4K5 MAPK14 MAPRE1 MAX MDC1 MDM2 MEF2C MEF2D MIF NCOA1 NEDD8 NFKB1 NR4A2 NR4A3 NR5A2 OPRM1 PGR PLAC8 PPARG PPOX PPP1CC PRDX2 PRKD1 PTGS2 RAD1 RAD9A RNF139 RORA S100A7 SHANK3 SHISA5 SMAD2 SMAD4 SMAD5 SPP1 SREBF2 TOP2A TP53 TXN TYK2 UCHL1 USP14 VTN WNK1 YWHAG 60 interactors: BBS10 BCL10 CARD11 CHUK COPS5 EIF2AK2 EZH2 FOS GPR25 HGS HIPK2 IKBKAP IKBKB IL17RD IRAK1 MAP2K4 MAP2K6 MAP3K14 MAP3K3 MAP3K5 MAP4K1 MAP4K4 MAPK14 MAPK6 MAPK8 MAPK8IP1 MAVS NAIP NDUFS6 NOD2 NRIP1 PEBP1 PELI3 PINK1 PPM1B PPM1L PPP2R1A PPP5C PRKAA1 PRKAB1 RBX1 RELA RNF19A ROR2 SMAD3 SMAD6 SMAD7 STAT3 STRADB TAB1 TAB2 TGFBR1 TNFRSF11A TRAF3IP2 TRAF6 TRIM8 VRK2 XIAP ZNF593 ZNF746
Entrez ID 10987 6885
HPRD ID 06888 04011
Ensembl ID ENSG00000121022 ENSG00000135341
Uniprot IDs Q92905 O43318
PDB IDs 4F7O 2EVA 2YIY 4GS6 4L3P 4L52 4L53
Enriched GO Terms of Interacting Partners?
Tagcloud ?
abeta  apdeltae9  app  bace1  brains  coimmunoprecipitation  colocalization  compartments  consequently  exists  forming  generation  implying  interacting  library  lipoprotein  multiprotein  neurotoxic  plaque  ranbp9  robustly  sapp  scaffold  sirnas  soluble  stabilizing  subcellular  supported  tripartite 
abrogated  accounts  bcr  called  card  card11  carma1  existence  feedback  generating  ikappab  ikk  ikkbeta  implies  kappab  late  maguk  mathematical  modeling  module  nf  residue  scaffolding  serine  steep  switch  switchlike  tak1  threshold 
Tagcloud (Difference) ?
abeta  apdeltae9  app  bace1  brains  coimmunoprecipitation  colocalization  compartments  consequently  exists  forming  generation  implying  interacting  library  lipoprotein  multiprotein  neurotoxic  plaque  ranbp9  robustly  sapp  scaffold  sirnas  soluble  stabilizing  subcellular  supported  tripartite 
abrogated  accounts  bcr  called  card  card11  carma1  existence  feedback  generating  ikappab  ikk  ikkbeta  implies  kappab  late  maguk  mathematical  modeling  module  nf  residue  scaffolding  serine  steep  switch  switchlike  tak1  threshold 
Tagcloud (Intersection) ?