NEK6 and SMURF2

  • Number of citations of the paper that reports this interaction (PMID 15761153)
  • 154
  • Data Source:
  • HPRD (in vivo)

NEK6

SMURF2

Gene Name NIMA-related kinase 6 SMAD specific E3 ubiquitin protein ligase 2
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 42 interactors: AES ANKRA2 ARHGAP33 ARRB1 ATF4 CCDC36 CCDC85B CDC42 CDK7 CIR1 ERCC6L2 FAM208B HSD17B14 IKZF1 IKZF3 INCA1 KCTD5 KRT31 KRT40 LNX1 LZTS2 NECAB2 NEK9 PAK6 PHF1 PIN1 PRAM1 PRDX3 PTN RBBP6 RPS6KB1 RPS7 SGK1 SMAD4 SMURF2 TCF4 TGFBR1 TNK2 TRIM23 TRIM27 TRIP4 XIAP 79 interactors: ACBD3 ACOX3 ANAPC5 ARHGAP5 ASH2L AXIN1 BTRC CANX CUEDC1 DAB2 DAZAP2 DGCR2 EGFR EPHA1 FAM175B FKBP4 FLNB GNG2 HDGFRP3 ING2 IRF3 IRF8 KLF5 LAPTM5 LATS1 MAVS NEK6 NKIRAS1 NRAS PPID PRICKLE1 PRICKLE2 RAB13 RAB14 RAB17 RAB22A RAB25 RAN RAP1B RASD2 RASL12 RHOA RHOD RLIM RNF11 RNF111 RNF2 RNF20 RPS27A RRAS2 RUNX2 RUNX3 SF3A2 SKIL SMAD1 SMAD2 SMAD3 SMAD5 SMAD6 SMAD7 SMAP1 SNRNP70 SOCS6 SPG20 SRSF4 TFPI2 TGFBR1 TMEM139 TNPO3 TRAF2 TRAF4 TSSK4 TXNIP UBC UBE2D1 UBE2D3 UBE2L3 YY1 ZBTB44
Entrez ID 10783 64750
HPRD ID 05348 06901
Ensembl ID ENSG00000119408
Uniprot IDs Q9HC98 Q96DE7 Q9HAU4
PDB IDs 1ZVD 2DJY 2JQZ 2KXQ 2LTZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
23a  abolishes  attenuated  attenuates  berberine  biogenesis  chromatin  detecting  g2  gadd45alpha  hcc  hepatocellular  immunoblotting  mature  mediate  mediating  microrna  mir  monitored  onto  p21  precursor  prediction  reveals  suppress  suppressive  transcript  upon  validation 
autoinhibitory  biochemical  c2  catalytic  controlled  domain  dysregulation  e3  e3s  framework  hect  impaired  interaction  intramolecular  ligases  magnetic  maintaining  nedd4  nmr  noncovalent  regulate  regulators  resonance  state  structural  terminal  transthiolation  ub  ubiquitin 
Tagcloud (Difference) ?
23a  abolishes  attenuated  attenuates  berberine  biogenesis  chromatin  detecting  g2  gadd45alpha  hcc  hepatocellular  immunoblotting  mature  mediate  mediating  microrna  mir  monitored  onto  p21  precursor  prediction  reveals  suppress  suppressive  transcript  upon  validation 
autoinhibitory  biochemical  c2  catalytic  controlled  domain  dysregulation  e3  e3s  framework  hect  impaired  interaction  intramolecular  ligases  magnetic  maintaining  nedd4  nmr  noncovalent  regulate  regulators  resonance  state  structural  terminal  transthiolation  ub  ubiquitin 
Tagcloud (Intersection) ?