CFL2 and SSH1

Number of citations of the paper that reports this interaction (PMID 12684437)
45

Data Source:
HPRD (in vivo)

		CFL2	SSH1
Gene Name		cofilin 2 (muscle)	slingshot protein phosphatase 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Actin Cytoskeleton Nuclear Matrix I Band Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Lamellipodium Midbody Cleavage Furrow
	Molecular Function	Actin Binding Protein Binding	DNA Binding Actin Binding Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity
	Biological Process	Actin Filament Depolymerization Positive Regulation Of Actin Filament Depolymerization Sarcomere Organization Muscle Cell Cellular Homeostasis Regulation Of Dendritic Spine Morphogenesis	Cell Morphogenesis Protein Dephosphorylation Regulation Of Actin Polymerization Or Depolymerization Regulation Of Lamellipodium Assembly Actin Cytoskeleton Organization Regulation Of Cellular Protein Metabolic Process Peptidyl-tyrosine Dephosphorylation Regulation Of Axonogenesis Cellular Response To ATP
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: ACTB ACTG1 CAP2 CFL1 DSTN LIMK1 POT1 SSH1	5 interactors: ACTB CFL1 CFL2 CORO1B DSTN
Entrez ID		1073	54434
HPRD ID		03262	09486
Ensembl ID		ENSG00000165410	ENSG00000084112
Uniprot IDs		Q549N0 Q9Y281	Q8WYL5
PDB IDs
Enriched GO Terms of Interacting Partners?		Ephrin Receptor Signaling Pathway Axon Guidance Organelle Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Cell Morphogenesis Axonogenesis Cytoskeleton Organization Axon Development Cell Morphogenesis Involved In Neuron Differentiation Actin Cytoskeleton Organization Chemotaxis Actin Filament-based Process Neuron Projection Morphogenesis Phagocytosis Fc Receptor Signaling Pathway Cell Morphogenesis Involved In Differentiation Immune Response-activating Cell Surface Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Generation Of Neurons Positive Regulation Of Actin Filament Depolymerization Regulation Of Cellular Component Size Neuron Projection Development Cell Projection Morphogenesis Neurogenesis Cell Part Morphogenesis Regulation Of Actin Cytoskeleton Organization Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Organelle Organization Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Neuron Development Positive Regulation Of Protein Depolymerization Actin Filament Depolymerization Immune Response-regulating Signaling Pathway Neuron Differentiation Regulation Of Cytoskeleton Organization Cell Projection Organization Nervous System Development Locomotion Anatomical Structure Morphogenesis Positive Regulation Of Protein Complex Disassembly Platelet Activation Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of Immune Response Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway	Positive Regulation Of Actin Filament Depolymerization Actin Filament Depolymerization Positive Regulation Of Protein Depolymerization Positive Regulation Of Protein Complex Disassembly Actin Filament Organization Regulation Of Actin Filament Depolymerization Regulation Of Actin Cytoskeleton Organization Actin Polymerization Or Depolymerization Regulation Of Actin Filament-based Process Regulation Of Protein Depolymerization Regulation Of Cytoskeleton Organization Regulation Of Protein Complex Disassembly Actin Cytoskeleton Organization Actin Filament-based Process Cellular Protein Complex Disassembly Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Protein Complex Disassembly Regulation Of Actin Filament Length Regulation Of Organelle Organization Regulation Of Dendritic Spine Morphogenesis Cytoskeleton Organization Regulation Of Cellular Component Size Regulation Of Dendritic Spine Development Organelle Organization Positive Regulation Of Organelle Organization Movement Of Cell Or Subcellular Component Regulation Of Cell Morphogenesis Regulation Of Cell Projection Organization Regulation Of Dendrite Morphogenesis Wound Healing Chemotaxis Ephrin Receptor Signaling Pathway Regulation Of Dendrite Development Regulation Of Cellular Component Organization Response To Wounding Protein Localization To Cell Leading Edge Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Ameboidal-type Cell Migration Positive Regulation Of Lamellipodium Morphogenesis Platelet Activation Actin Filament Branching Cell Projection Organization Phagocytosis Fc Receptor Signaling Pathway Regulation Of Lamellipodium Morphogenesis Locomotion Immune Response-activating Cell Surface Receptor Signaling Pathway
Tagcloud ?		adipogenesis adipogenic adipose ankrd1 ankyrin bovine bulls cofilin dehydrogenase differentially hspb1 lactate ldhb likewise mlc1 monitored myogenesis myogenic myosin repeat skeletal steers taldo1 tenfold testosterone threefold transaldolase twofold vary	10mum 20days aging cofilin1 compartments cytoskeleton decline dysregulation inactivation interestingly knock lim limk1 mef mefdko occurring pcns plasticity presenilin ps1 regard remodeling rescued safely secretase shed shh1 slingshot stream
Tagcloud (Difference) ?		adipogenesis adipogenic adipose ankrd1 ankyrin bovine bulls cofilin dehydrogenase differentially hspb1 lactate ldhb likewise mlc1 monitored myogenesis myogenic myosin repeat skeletal steers taldo1 tenfold testosterone threefold transaldolase twofold vary	10mum 20days aging cofilin1 compartments cytoskeleton decline dysregulation inactivation interestingly knock lim limk1 mef mefdko occurring pcns plasticity presenilin ps1 regard remodeling rescued safely secretase shed shh1 slingshot stream
Tagcloud (Intersection) ?