EXOC5 and ICA1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		EXOC5	ICA1
Gene Name		exocyst complex component 5	islet cell autoantigen 1, 69kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol	Golgi Membrane Cytoplasm Cytosol Cell Junction Transport Vesicle Membrane Secretory Granule Membrane Synaptic Vesicle Membrane
	Molecular Function	Ral GTPase Binding Protein N-terminus Binding	Molecular_function Protein Domain Specific Binding
	Biological Process	Exocytosis Post-Golgi Vesicle-mediated Transport Organelle Organization Protein Transport Cellular Protein Metabolic Process Vesicle Docking Membrane Organization	Neurotransmitter Transport
Pathways		Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing
Drugs
Diseases
GWAS		Alcohol consumption ( 23743675)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		30 interactors: ACTR3B ADCK1 ARF6 BARD1 BRMS1L C9orf9 CCDC102B CCDC67 CDH2 EDRF1 ENO2 FRMD6 HDDC3 ICA1 KXD1 MAGEA6 OAS1 PRKCG PTK6 PYCARD RAB14 RAB4A RAB4B RALA SOX10 TBX21 TNPO2 TTC23L TXLNB TXNL4A	6 interactors: CCDC28A EXOC5 ING5 MBD3 RAB2A RAB2B
Entrez ID		10640	3382
HPRD ID		07258	00971
Ensembl ID		ENSG00000070367	ENSG00000003147
Uniprot IDs		F8W9B8 O00471 Q8IW24	Q05084 Q96HG3
PDB IDs
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Regulation Of Vesicle-mediated Transport Regulation Of Endocytosis Ras Protein Signal Transduction Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Positive Regulation Of Cellular Component Biogenesis Small GTPase Mediated Signal Transduction Intracellular Signal Transduction Actin Filament-based Process Regulation Of Rac Protein Signal Transduction Positive Regulation Of Protein Complex Assembly Regulation Of Actin Filament-based Process Regulation Of Actin Filament Polymerization Positive Regulation Of Mismatch Repair Phagolysosome Assembly Involved In Apoptotic Cell Clearance Regulation Of Filopodium Assembly Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Myeloid Dendritic Cell Activation Involved In Immune Response Regulation Of Mismatch Repair Positive Regulation Of Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Negative Regulation Of MRNA 3'-end Processing Epithelial Cell Differentiation Cellular Protein Localization Response To Virus Cellular Response To Organic Substance	Rab Protein Signal Transduction Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Ras Protein Signal Transduction Peptidyl-lysine Modification Methylation-dependent Chromatin Silencing Organelle Organization Protein Transport Establishment Of Protein Localization Intracellular Transport Histone Modification Protein Localization Establishment Of Localization In Cell Chromatin Modification Small GTPase Mediated Signal Transduction Chromatin Silencing
Tagcloud ?			6x10 7x10 aicda bank1 card8 ccl11 eotaxin fisher formations gc germinal ikbke il17a keratoconjunctivitis lacrimal minor norwegian pkn1 pss rheumatic salivary sicca sjogren snps suggestive suggestively swedish tank xerostomia
Tagcloud (Difference) ?			6x10 7x10 aicda bank1 card8 ccl11 eotaxin fisher formations gc germinal ikbke il17a keratoconjunctivitis lacrimal minor norwegian pkn1 pss rheumatic salivary sicca sjogren snps suggestive suggestively swedish tank xerostomia
Tagcloud (Intersection) ?