POLR3F and PRPF4B

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		POLR3F	PRPF4B
Gene Name		polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa	pre-mRNA processing factor 4B
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Gene Ontology Annotations	Cellular Component	Nucleoplasm DNA-directed RNA Polymerase III Complex Cytosol	Nucleoplasm Chromosome Catalytic Step 2 Spliceosome
	Molecular Function	RNA Polymerase III Activity DNA Binding DNA-directed RNA Polymerase Activity Protein Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase III Promoter Transcription From RNA Polymerase III Promoter Transcription Elongation From RNA Polymerase III Promoter Termination Of RNA Polymerase III Transcription Gene Expression Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus	MRNA Splicing, Via Spliceosome Protein Phosphorylation RNA Splicing
Pathways		RNA Polymerase III Transcription Termination RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Initiation From Type 2 Promoter Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: BDP1 BRF1 C14orf1 GTF3C4 KAT5 LRIF1 PRPF4B STC2 SUV39H2 TBP UBE2G2 WDR89	6 interactors: HSPB3 KLF13 PNN POLR3F SRSF1 YWHAG
Entrez ID		10621	8899
HPRD ID		15156	09087
Ensembl ID		ENSG00000132664	ENSG00000112739
Uniprot IDs		Q9H1D9	Q13523
PDB IDs		2DK5 2YU3	4IAN 4IFC 4IIR 4IJP
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase III Promoter TRNA Transcription Transcription Initiation From RNA Polymerase III Promoter RNA Metabolic Process Transcription, DNA-templated Gene Expression Biosynthetic Process RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RRNA Transcription DNA-templated Transcription, Initiation Nucleobase-containing Compound Metabolic Process Peptidyl-lysine Modification Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Peptidyl-amino Acid Modification Histone Modification Nitrogen Compound Metabolic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Proepicardium Development Internal Protein Amino Acid Acetylation Cellular Protein Modification Process Protein Acetylation Negative Regulation Of Gene Expression Histone H3-K9 Dimethylation Chromatin Modification Regulation Of Gene Expression 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter Placenta Development Chromatin Organization Histone H3-K9 Trimethylation Chorio-allantoic Fusion Peptidyl-lysine Dimethylation Regulation Of Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Cellular Macromolecule Catabolic Process Proteasomal Protein Catabolic Process DNA Damage Response, Signal Transduction Resulting In Transcription Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process	DNA-templated Transcription, Termination Transcription, DNA-templated MRNA 5'-splice Site Recognition RNA Biosynthetic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Erythrocyte Differentiation RNA Splicing
Tagcloud ?			abstract acquired anthracyclines checkpoint correlates efflux erbb2 her2 knock microtubule microtubules mitotic modifier modifiers ovarian platinum positively prp4k sac serous snrnp spindle splicing subgroup taxane taxanes treat tumours u5
Tagcloud (Difference) ?			abstract acquired anthracyclines checkpoint correlates efflux erbb2 her2 knock microtubule microtubules mitotic modifier modifiers ovarian platinum positively prp4k sac serous snrnp spindle splicing subgroup taxane taxanes treat tumours u5
Tagcloud (Intersection) ?