CENPB and PARP2

Number of citations of the paper that reports this interaction (PMID 12217960)
17

Data Source:
HPRD (in vivo)

		CENPB	PARP2
Gene Name		centromere protein B, 80kDa	poly (ADP-ribose) polymerase 2
Image
Gene Ontology Annotations	Cellular Component	Chromosome, Centromeric Region Nucleus Chromosome	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Chromatin Binding Satellite DNA Binding Centromeric DNA Binding Sequence-specific DNA Binding	DNA Binding NAD+ ADP-ribosyltransferase Activity Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated	DNA Repair Base-excision Repair Protein ADP-ribosylation Extrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: ANXA7 APP CDKN1A CSNK2B FBXO25 GADD45A GFI1B GSK3B HAND2 NR3C1 PARP1 PARP2 PIN1 RPS6KA6 SMN1 TAC1 TK1	6 interactors: BUB3 CASP8 CENPA CENPB PARP1 XRCC1
Entrez ID		1059	10038
HPRD ID		00314	09660
Ensembl ID		ENSG00000125817	ENSG00000129484
Uniprot IDs		P07199	Q9UGN5
PDB IDs		1BW6 1HLV 1UFI	3KCZ 3KJD
Enriched GO Terms of Interacting Partners?		Regulation Of Binding Negative Regulation Of Phosphorylation Regulation Of Signaling Anatomical Structure Development Cellular Metabolic Process Response To External Stimulus Positive Regulation Of Transcription Regulatory Region DNA Binding Regulation Of Phosphorylation Response To Organic Substance System Development Positive Regulation Of Cellular Metabolic Process Response To Stress Regulation Of DNA Binding Response To Hormone Apoptotic Process Regulation Of Signal Transduction Regulation Of Phosphorus Metabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of Cellular Metabolic Process Developmental Process Behavior Programmed Cell Death Cell Death Death Regulation Of Protein Phosphorylation Response To Abiotic Stimulus Multicellular Organismal Development Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Binding Tube Development Positive Regulation Of Protein Phosphorylation Suckling Behavior Regulation Of Protein Kinase Activity Cellular Protein Modification Process Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of Protein Metabolic Process Axon Guidance Protein ADP-ribosylation Regulation Of Kinase Activity Response To Glucocorticoid Signal Transduction Negative Regulation Of MAPK Cascade Positive Regulation Of Metabolic Process Response To Corticosteroid Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Import Into Nucleus Cellular Response To DNA Damage Stimulus Positive Regulation Of Phosphorylation Response To Organic Cyclic Compound Response To Inorganic Substance	Macrophage Differentiation Base-excision Repair Myeloid Leukocyte Differentiation Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Regulation Of Growth Rate Protein Poly-ADP-ribosylation TRAIL-activated Apoptotic Signaling Pathway
Tagcloud ?		agreement altman asian bland cenpa cohen fibrillarin iif immunoassay interstitial kappa ku lia limits nc ncs nor90 oa outside plots pmscl100 ro52 ro60 rp155 sle ssc stored telangiectasia utility	abt actively adp azd bsi continues crystal detailed explored guide heightened indications inhibitors insight manifesting modes parp1 parp5a parp5b poly rational relevance ribose stranded tankyrase tnks1 tnks2 valuable
Tagcloud (Difference) ?		agreement altman asian bland cenpa cohen fibrillarin iif immunoassay interstitial kappa ku lia limits nc ncs nor90 oa outside plots pmscl100 ro52 ro60 rp155 sle ssc stored telangiectasia utility	abt actively adp azd bsi continues crystal detailed explored guide heightened indications inhibitors insight manifesting modes parp1 parp5a parp5b poly rational relevance ribose stranded tankyrase tnks1 tnks2 valuable
Tagcloud (Intersection) ?